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FBXO46 (F-box protein 46)

Identity

Alias (NCBI)20D7-FC4
FBXO34L
Fbx46
HGNC (Hugo) FBXO46
HGNC Alias symb20D7-FC4
Fbx46
HGNC Previous nameFBXO34L
HGNC Previous nameF-box only protein 34-like
LocusID (NCBI) 23403
Atlas_Id 47311
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 45710629 and ends at 45723496 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FBXO46 (19q13.32)::SNRPD2 (19q13.32)FBXO46 (19q13.32)::SYMPK (19q13.32)FBXO46 19q13.32::SYMPK 19q13.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FBXO46   25069
Cards
Entrez_Gene (NCBI)FBXO46    F-box protein 46
Aliases20D7-FC4; FBXO34L; Fbx46
GeneCards (Weizmann)FBXO46
Ensembl hg19 (Hinxton)ENSG00000177051 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177051 [Gene_View]  ENSG00000177051 [Sequence]  chr19:45710629-45723496 [Contig_View]  FBXO46 [Vega]
ICGC DataPortalENSG00000177051
TCGA cBioPortalFBXO46
AceView (NCBI)FBXO46
Genatlas (Paris)FBXO46
SOURCE (Princeton)FBXO46
Genetics Home Reference (NIH)FBXO46
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO46  -     chr19:45710629-45723496 -  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO46  -     19q13.32   [Description]    (hg19-Feb_2009)
GoldenPathFBXO46 - 19q13.32 [CytoView hg19]  FBXO46 - 19q13.32 [CytoView hg38]
ImmunoBaseENSG00000177051
Genome Data Viewer NCBIFBXO46 [Mapview hg19]  
OMIM609117   
Gene and transcription
Genbank (Entrez)BC008046 BC013570 BC021978 BC046245 Y10936
RefSeq transcript (Entrez)NM_001080469 NM_001329632 NM_001329633 NM_001329634
Consensus coding sequences : CCDS (NCBI)FBXO46
Gene ExpressionFBXO46 [ NCBI-GEO ]   FBXO46 [ EBI - ARRAY_EXPRESS ]   FBXO46 [ SEEK ]   FBXO46 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO46 [ Firebrowse - Broad ]
GenevisibleExpression of FBXO46 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23403
GTEX Portal (Tissue expression)FBXO46
Human Protein AtlasENSG00000177051-FBXO46 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PJ61   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PJ61  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PJ61
PhosPhoSitePlusQ6PJ61
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)   
Domains : Interpro (EBI)F-box-like_dom_sf    F-box_dom    FBXO34/46   
Domain families : Pfam (Sanger)F-box-like (PF12937)   
Domain families : Pfam (NCBI)pfam12937   
Domain families : Smart (EMBL)FBOX (SM00256)  
Conserved Domain (NCBI)FBXO46
SuperfamilyQ6PJ61
AlphaFold pdb e-kbQ6PJ61   
Human Protein Atlas [tissue]ENSG00000177051-FBXO46 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q6PJ61
IntAct (EBI)Q6PJ61
BioGRIDFBXO46
STRING (EMBL)FBXO46
ZODIACFBXO46
Ontologies - Pathways
QuickGOQ6PJ61
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkFBXO46
Atlas of Cancer Signalling NetworkFBXO46
Wikipedia pathwaysFBXO46
Orthology - Evolution
OrthoDB23403
GeneTree (enSembl)ENSG00000177051
Phylogenetic Trees/Animal Genes : TreeFamFBXO46
Homologs : HomoloGeneFBXO46
Homology/Alignments : Family Browser (UCSC)FBXO46
Gene fusions - Rearrangements
Fusion : MitelmanFBXO46::SYMPK [19q13.32/19q13.32]  
Fusion : QuiverFBXO46
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO46
dbVarFBXO46
ClinVarFBXO46
MonarchFBXO46
1000_GenomesFBXO46 
Exome Variant ServerFBXO46
GNOMAD BrowserENSG00000177051
Varsome BrowserFBXO46
ACMGFBXO46 variants
VarityQ6PJ61
Genomic Variants (DGV)FBXO46 [DGVbeta]
DECIPHERFBXO46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO46 
Mutations
ICGC Data PortalFBXO46 
TCGA Data PortalFBXO46 
Broad Tumor PortalFBXO46
OASIS PortalFBXO46 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO46  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFBXO46
Mutations and Diseases : HGMDFBXO46
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFBXO46
DgiDB (Drug Gene Interaction Database)FBXO46
DoCM (Curated mutations)FBXO46
CIViC (Clinical Interpretations of Variants in Cancer)FBXO46
Cancer3DFBXO46
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609117   
Orphanet
DisGeNETFBXO46
MedgenFBXO46
Genetic Testing Registry FBXO46
NextProtQ6PJ61 [Medical]
GENETestsFBXO46
Target ValidationFBXO46
Huge Navigator FBXO46 [HugePedia]
ClinGenFBXO46
Clinical trials, drugs, therapy
MyCancerGenomeFBXO46
Protein Interactions : CTDFBXO46
Pharm GKB GenePA134985344
PharosQ6PJ61
Clinical trialFBXO46
Miscellaneous
canSAR (ICR)FBXO46
HarmonizomeFBXO46
ARCHS4FBXO46
DataMed IndexFBXO46
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFBXO46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jan 17 15:24:29 CET 2022

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