Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FBXW10 (F-box and WD repeat domain containing 10)

Identity

Alias_namesC17orf1
C17orf1A
chromosome 17 open reading frame 1A
F-box and WD-40 domain protein 10
Alias_symbol (synonym)SM2SH2
HREP
Fbw10
Other aliasSM25H2
HGNC (Hugo) FBXW10
LocusID (NCBI) 10517
Atlas_Id 63338
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 18647326 and ends at 18682662 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PRPSAP2 (17p11.2) / FBXW10 (17p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXW10   1211
Cards
Entrez_Gene (NCBI)FBXW10  10517  F-box and WD repeat domain containing 10
AliasesFbw10; HREP; SM25H2; SM2SH2
GeneCards (Weizmann)FBXW10
Ensembl hg19 (Hinxton)ENSG00000171931 [Gene_View]  chr17:18647326-18682662 [Contig_View]  FBXW10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171931 [Gene_View]  chr17:18647326-18682662 [Contig_View]  FBXW10 [Vega]
ICGC DataPortalENSG00000171931
TCGA cBioPortalFBXW10
AceView (NCBI)FBXW10
Genatlas (Paris)FBXW10
WikiGenes10517
SOURCE (Princeton)FBXW10
Genetics Home Reference (NIH)FBXW10
Genomic and cartography
GoldenPath hg19 (UCSC)FBXW10  -     chr17:18647326-18682662 +  17p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FBXW10  -     17p11.2   [Description]    (hg38-Dec_2013)
EnsemblFBXW10 - 17p11.2 [CytoView hg19]  FBXW10 - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIFBXW10 [Mapview hg19]  FBXW10 [Mapview hg38]
OMIM611679   
Gene and transcription
Genbank (Entrez)AK310383 AL136822 AY729024 BC028364 BI828401
RefSeq transcript (Entrez)NM_001267585 NM_001267586 NM_031456
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)FBXW10
Cluster EST : UnigeneHs.592128 [ NCBI ]
CGAP (NCI)Hs.592128
Alternative Splicing GalleryENSG00000171931
Gene ExpressionFBXW10 [ NCBI-GEO ]   FBXW10 [ EBI - ARRAY_EXPRESS ]   FBXW10 [ SEEK ]   FBXW10 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXW10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10517
GTEX Portal (Tissue expression)FBXW10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5XX13   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5XX13  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5XX13
Splice isoforms : SwissVarQ5XX13
PhosPhoSitePlusQ5XX13
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)F-box_dom    G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)FBXW10
DMDM Disease mutations10517
Blocks (Seattle)FBXW10
SuperfamilyQ5XX13
Human Protein AtlasENSG00000171931
Peptide AtlasQ5XX13
HPRD06851
IPIIPI00852606   IPI00290837   IPI00027801   IPI00789588   
Protein Interaction databases
DIP (DOE-UCLA)Q5XX13
IntAct (EBI)Q5XX13
FunCoupENSG00000171931
BioGRIDFBXW10
STRING (EMBL)FBXW10
ZODIACFBXW10
Ontologies - Pathways
QuickGOQ5XX13
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkFBXW10
Atlas of Cancer Signalling NetworkFBXW10
Wikipedia pathwaysFBXW10
Orthology - Evolution
OrthoDB10517
GeneTree (enSembl)ENSG00000171931
Phylogenetic Trees/Animal Genes : TreeFamFBXW10
HOVERGENQ5XX13
HOGENOMQ5XX13
Homologs : HomoloGeneFBXW10
Homology/Alignments : Family Browser (UCSC)FBXW10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXW10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXW10
dbVarFBXW10
ClinVarFBXW10
1000_GenomesFBXW10 
Exome Variant ServerFBXW10
ExAC (Exome Aggregation Consortium)FBXW10 (select the gene name)
Genetic variants : HAPMAP10517
Genomic Variants (DGV)FBXW10 [DGVbeta]
DECIPHER (Syndromes)17:18647326-18682662  ENSG00000171931
CONAN: Copy Number AnalysisFBXW10 
Mutations
ICGC Data PortalFBXW10 
TCGA Data PortalFBXW10 
Broad Tumor PortalFBXW10
OASIS PortalFBXW10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXW10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXW10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXW10
DgiDB (Drug Gene Interaction Database)FBXW10
DoCM (Curated mutations)FBXW10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXW10 (select a term)
intoGenFBXW10
Cancer3DFBXW10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611679   
Orphanet
MedgenFBXW10
Genetic Testing Registry FBXW10
NextProtQ5XX13 [Medical]
TSGene10517
GENETestsFBXW10
Huge Navigator FBXW10 [HugePedia]
snp3D : Map Gene to Disease10517
BioCentury BCIQFBXW10
ClinGenFBXW10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10517
Chemical/Pharm GKB GenePA25575
Clinical trialFBXW10
Miscellaneous
canSAR (ICR)FBXW10 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXW10
EVEXFBXW10
GoPubMedFBXW10
iHOPFBXW10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:04:38 CET 2017

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