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FBXW5 (F-box and WD repeat domain containing 5)

Identity

Alias_namesF-box and WD-40 domain protein 5
Alias_symbol (synonym)DKFZP434B205
MGC20962
Fbw5
Other alias
HGNC (Hugo) FBXW5
LocusID (NCBI) 54461
Atlas_Id 63343
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 139834885 and ends at 139839206 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FBXW5 (9q34.3) / PSMB10 (16q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXW5   13613
Cards
Entrez_Gene (NCBI)FBXW5  54461  F-box and WD repeat domain containing 5
AliasesFbw5
GeneCards (Weizmann)FBXW5
Ensembl hg19 (Hinxton)ENSG00000159069 [Gene_View]  chr9:139834885-139839206 [Contig_View]  FBXW5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000159069 [Gene_View]  chr9:139834885-139839206 [Contig_View]  FBXW5 [Vega]
ICGC DataPortalENSG00000159069
TCGA cBioPortalFBXW5
AceView (NCBI)FBXW5
Genatlas (Paris)FBXW5
WikiGenes54461
SOURCE (Princeton)FBXW5
Genetics Home Reference (NIH)FBXW5
Genomic and cartography
GoldenPath hg19 (UCSC)FBXW5  -     chr9:139834885-139839206 -  9q34.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FBXW5  -     9q34.3   [Description]    (hg38-Dec_2013)
EnsemblFBXW5 - 9q34.3 [CytoView hg19]  FBXW5 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBIFBXW5 [Mapview hg19]  FBXW5 [Mapview hg38]
OMIM609072   
Gene and transcription
Genbank (Entrez)AB209726 AF217998 AF258569 AK026081 AK315738
RefSeq transcript (Entrez)NM_018998 NM_178225 NM_178226
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_029580 NT_008470 NW_004929369
Consensus coding sequences : CCDS (NCBI)FBXW5
Cluster EST : UnigeneHs.522507 [ NCBI ]
CGAP (NCI)Hs.522507
Alternative Splicing GalleryENSG00000159069
Gene ExpressionFBXW5 [ NCBI-GEO ]   FBXW5 [ EBI - ARRAY_EXPRESS ]   FBXW5 [ SEEK ]   FBXW5 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXW5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54461
GTEX Portal (Tissue expression)FBXW5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969U6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969U6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969U6
Splice isoforms : SwissVarQ969U6
PhosPhoSitePlusQ969U6
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)F-box_dom    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)F-box-like (PF12937)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam12937    pfam00400   
Domain families : Smart (EMBL)FBOX (SM00256)  WD40 (SM00320)  
Conserved Domain (NCBI)FBXW5
DMDM Disease mutations54461
Blocks (Seattle)FBXW5
SuperfamilyQ969U6
Human Protein AtlasENSG00000159069
Peptide AtlasQ969U6
HPRD10955
IPIIPI00056507   IPI00514362   IPI00645389   IPI00374556   
Protein Interaction databases
DIP (DOE-UCLA)Q969U6
IntAct (EBI)Q969U6
FunCoupENSG00000159069
BioGRIDFBXW5
STRING (EMBL)FBXW5
ZODIACFBXW5
Ontologies - Pathways
QuickGOQ969U6
Ontology : AmiGOprotein binding  cytoplasm  mitotic nuclear division  protein ubiquitination  protein ubiquitination  SCF ubiquitin ligase complex  protein kinase binding  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  centrosome duplication  Cul4-RING E3 ubiquitin ligase complex  
Ontology : EGO-EBIprotein binding  cytoplasm  mitotic nuclear division  protein ubiquitination  protein ubiquitination  SCF ubiquitin ligase complex  protein kinase binding  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  centrosome duplication  Cul4-RING E3 ubiquitin ligase complex  
NDEx NetworkFBXW5
Atlas of Cancer Signalling NetworkFBXW5
Wikipedia pathwaysFBXW5
Orthology - Evolution
OrthoDB54461
GeneTree (enSembl)ENSG00000159069
Phylogenetic Trees/Animal Genes : TreeFamFBXW5
HOVERGENQ969U6
HOGENOMQ969U6
Homologs : HomoloGeneFBXW5
Homology/Alignments : Family Browser (UCSC)FBXW5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXW5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXW5
dbVarFBXW5
ClinVarFBXW5
1000_GenomesFBXW5 
Exome Variant ServerFBXW5
ExAC (Exome Aggregation Consortium)FBXW5 (select the gene name)
Genetic variants : HAPMAP54461
Genomic Variants (DGV)FBXW5 [DGVbeta]
DECIPHER (Syndromes)9:139834885-139839206  ENSG00000159069
CONAN: Copy Number AnalysisFBXW5 
Mutations
ICGC Data PortalFBXW5 
TCGA Data PortalFBXW5 
Broad Tumor PortalFBXW5
OASIS PortalFBXW5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXW5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXW5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXW5
DgiDB (Drug Gene Interaction Database)FBXW5
DoCM (Curated mutations)FBXW5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXW5 (select a term)
intoGenFBXW5
Cancer3DFBXW5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609072   
Orphanet
MedgenFBXW5
Genetic Testing Registry FBXW5
NextProtQ969U6 [Medical]
TSGene54461
GENETestsFBXW5
Huge Navigator FBXW5 [HugePedia]
snp3D : Map Gene to Disease54461
BioCentury BCIQFBXW5
ClinGenFBXW5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54461
Chemical/Pharm GKB GenePA134928070
Clinical trialFBXW5
Miscellaneous
canSAR (ICR)FBXW5 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXW5
EVEXFBXW5
GoPubMedFBXW5
iHOPFBXW5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:04:39 CET 2017

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