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FCER1A (Fc fragment of IgE receptor Ia)

Identity

Alias_namesFCE1A
Fc fragment of IgE
Other aliasFcERI
HGNC (Hugo) FCER1A
LocusID (NCBI) 2205
Atlas_Id 45948
Location 1q23.2  [Link to chromosome band 1q23]
Location_base_pair Starts at 159289714 and ends at 159308224 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCER1A   3609
Cards
Entrez_Gene (NCBI)FCER1A  2205  Fc fragment of IgE receptor Ia
AliasesFCE1A; FcERI
GeneCards (Weizmann)FCER1A
Ensembl hg19 (Hinxton)ENSG00000179639 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179639 [Gene_View]  chr1:159289714-159308224 [Contig_View]  FCER1A [Vega]
ICGC DataPortalENSG00000179639
TCGA cBioPortalFCER1A
AceView (NCBI)FCER1A
Genatlas (Paris)FCER1A
WikiGenes2205
SOURCE (Princeton)FCER1A
Genetics Home Reference (NIH)FCER1A
Genomic and cartography
GoldenPath hg38 (UCSC)FCER1A  -     chr1:159289714-159308224 +  1q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCER1A  -     1q23.2   [Description]    (hg19-Feb_2009)
EnsemblFCER1A - 1q23.2 [CytoView hg19]  FCER1A - 1q23.2 [CytoView hg38]
Mapping of homologs : NCBIFCER1A [Mapview hg19]  FCER1A [Mapview hg38]
OMIM147140   
Gene and transcription
Genbank (Entrez)BC005912 BC015185 BC015195 DQ893131 DQ896411
RefSeq transcript (Entrez)NM_002001
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCER1A
Cluster EST : UnigeneHs.897 [ NCBI ]
CGAP (NCI)Hs.897
Alternative Splicing GalleryENSG00000179639
Gene ExpressionFCER1A [ NCBI-GEO ]   FCER1A [ EBI - ARRAY_EXPRESS ]   FCER1A [ SEEK ]   FCER1A [ MEM ]
Gene Expression Viewer (FireBrowse)FCER1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2205
GTEX Portal (Tissue expression)FCER1A
Human Protein AtlasENSG00000179639-FCER1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12319   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12319  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12319
Splice isoforms : SwissVarP12319
PhosPhoSitePlusP12319
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)FCER1A
DMDM Disease mutations2205
Blocks (Seattle)FCER1A
PDB (SRS)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
PDB (PDBSum)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
PDB (IMB)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
PDB (RSDB)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
Structural Biology KnowledgeBase1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
SCOP (Structural Classification of Proteins)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
CATH (Classification of proteins structures)1ALS    1ALT    1F2Q    1F6A    1J86    1J87    1J88    1J89    1RPQ    2Y7Q   
SuperfamilyP12319
Human Protein Atlas [tissue]ENSG00000179639-FCER1A [tissue]
Peptide AtlasP12319
HPRD00917
IPIIPI00549768   IPI00023508   
Protein Interaction databases
DIP (DOE-UCLA)P12319
IntAct (EBI)P12319
FunCoupENSG00000179639
BioGRIDFCER1A
STRING (EMBL)FCER1A
ZODIACFCER1A
Ontologies - Pathways
QuickGOP12319
Ontology : AmiGOpositive regulation of type I hypersensitivity  serotonin secretion  intracellular  plasma membrane  integral component of plasma membrane  activation of JUN kinase activity  external side of plasma membrane  cell surface  leukotriene biosynthetic process  IgE receptor activity  IgE binding  Fc-epsilon receptor signaling pathway  positive regulation of mast cell degranulation  positive regulation of interleukin-3 biosynthetic process  positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of calcium-mediated signaling  
Ontology : EGO-EBIpositive regulation of type I hypersensitivity  serotonin secretion  intracellular  plasma membrane  integral component of plasma membrane  activation of JUN kinase activity  external side of plasma membrane  cell surface  leukotriene biosynthetic process  IgE receptor activity  IgE binding  Fc-epsilon receptor signaling pathway  positive regulation of mast cell degranulation  positive regulation of interleukin-3 biosynthetic process  positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process  positive regulation of peptidyl-tyrosine phosphorylation  positive regulation of calcium-mediated signaling  
Pathways : BIOCARTAFc Epsilon Receptor I Signaling in Mast Cells [Genes]   
Pathways : KEGGFc epsilon RI signaling pathway    Asthma   
NDEx NetworkFCER1A
Atlas of Cancer Signalling NetworkFCER1A
Wikipedia pathwaysFCER1A
Orthology - Evolution
OrthoDB2205
GeneTree (enSembl)ENSG00000179639
Phylogenetic Trees/Animal Genes : TreeFamFCER1A
HOVERGENP12319
HOGENOMP12319
Homologs : HomoloGeneFCER1A
Homology/Alignments : Family Browser (UCSC)FCER1A
Gene fusions - Rearrangements
Tumor Fusion PortalFCER1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCER1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCER1A
dbVarFCER1A
ClinVarFCER1A
1000_GenomesFCER1A 
Exome Variant ServerFCER1A
ExAC (Exome Aggregation Consortium)ENSG00000179639
GNOMAD BrowserENSG00000179639
Genetic variants : HAPMAP2205
Genomic Variants (DGV)FCER1A [DGVbeta]
DECIPHERFCER1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCER1A 
Mutations
ICGC Data PortalFCER1A 
TCGA Data PortalFCER1A 
Broad Tumor PortalFCER1A
OASIS PortalFCER1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCER1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCER1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCER1A
DgiDB (Drug Gene Interaction Database)FCER1A
DoCM (Curated mutations)FCER1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCER1A (select a term)
intoGenFCER1A
Cancer3DFCER1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147140   
Orphanet
DisGeNETFCER1A
MedgenFCER1A
Genetic Testing Registry FCER1A
NextProtP12319 [Medical]
TSGene2205
GENETestsFCER1A
Target ValidationFCER1A
Huge Navigator FCER1A [HugePedia]
snp3D : Map Gene to Disease2205
BioCentury BCIQFCER1A
ClinGenFCER1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2205
Chemical/Pharm GKB GenePA28056
Clinical trialFCER1A
Miscellaneous
canSAR (ICR)FCER1A (select the gene name)
Probes
Litterature
PubMed128 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCER1A
EVEXFCER1A
GoPubMedFCER1A
iHOPFCER1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:13:05 CET 2017

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