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FCER1G (Fc fragment of IgE receptor Ig)

Identity

Alias_namesFc fragment of IgE
Other aliasFCRG
HGNC (Hugo) FCER1G
LocusID (NCBI) 2207
Atlas_Id 50245
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161185087 and ends at 161189038 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PTPRJ (11p11.2) / FCER1G (1q23.3)SF3B1 (2q33.1) / FCER1G (1q23.3)PTPRJ 11p11.2 / FCER1G 1q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCER1G   3611
Cards
Entrez_Gene (NCBI)FCER1G  2207  Fc fragment of IgE receptor Ig
AliasesFCRG
GeneCards (Weizmann)FCER1G
Ensembl hg19 (Hinxton)ENSG00000158869 [Gene_View]  chr1:161185087-161189038 [Contig_View]  FCER1G [Vega]
Ensembl hg38 (Hinxton)ENSG00000158869 [Gene_View]  chr1:161185087-161189038 [Contig_View]  FCER1G [Vega]
ICGC DataPortalENSG00000158869
TCGA cBioPortalFCER1G
AceView (NCBI)FCER1G
Genatlas (Paris)FCER1G
WikiGenes2207
SOURCE (Princeton)FCER1G
Genetics Home Reference (NIH)FCER1G
Genomic and cartography
GoldenPath hg19 (UCSC)FCER1G  -     chr1:161185087-161189038 +  1q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FCER1G  -     1q23.3   [Description]    (hg38-Dec_2013)
EnsemblFCER1G - 1q23.3 [CytoView hg19]  FCER1G - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIFCER1G [Mapview hg19]  FCER1G [Mapview hg38]
OMIM147139   
Gene and transcription
Genbank (Entrez)AK307102 BC033872 DQ890782 EU176502 M33195
RefSeq transcript (Entrez)NM_004106
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_029043 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)FCER1G
Cluster EST : UnigeneHs.433300 [ NCBI ]
CGAP (NCI)Hs.433300
Alternative Splicing GalleryENSG00000158869
Gene ExpressionFCER1G [ NCBI-GEO ]   FCER1G [ EBI - ARRAY_EXPRESS ]   FCER1G [ SEEK ]   FCER1G [ MEM ]
Gene Expression Viewer (FireBrowse)FCER1G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2207
GTEX Portal (Tissue expression)FCER1G
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30273   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30273  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30273
Splice isoforms : SwissVarP30273
PhosPhoSitePlusP30273
Domaine pattern : Prosite (Expaxy)ITAM_1 (PS51055)   
Domains : Interpro (EBI)CR3_zeta/IgE_Fc_rcpt_gamma    Phos_immunorcpt_sig_ITAM   
Domain families : Pfam (Sanger)ITAM (PF02189)    TCR_zetazeta (PF11628)   
Domain families : Pfam (NCBI)pfam02189    pfam11628   
Domain families : Smart (EMBL)ITAM (SM00077)  
Conserved Domain (NCBI)FCER1G
DMDM Disease mutations2207
Blocks (Seattle)FCER1G
SuperfamilyP30273
Human Protein AtlasENSG00000158869
Peptide AtlasP30273
HPRD00916
IPIIPI00025804   IPI00644236   
Protein Interaction databases
DIP (DOE-UCLA)P30273
IntAct (EBI)P30273
FunCoupENSG00000158869
BioGRIDFCER1G
STRING (EMBL)FCER1G
ZODIACFCER1G
Ontologies - Pathways
QuickGOP30273
Ontology : AmiGOpositive regulation of type IIa hypersensitivity  positive regulation of type III hypersensitivity  positive regulation of type I hypersensitivity  stimulatory C-type lectin receptor signaling pathway  neutrophil activation involved in immune response  T cell differentiation involved in immune response  Fc receptor mediated stimulatory signaling pathway  serotonin secretion by platelet  protein binding  plasma membrane  integral component of plasma membrane  phagocytosis, engulfment  integrin-mediated signaling pathway  blood coagulation  external side of plasma membrane  cell surface  regulation of platelet activation  immunoglobulin mediated immune response  IgE receptor activity  IgE binding  IgG binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  platelet activation  neutrophil chemotaxis  receptor internalization  positive regulation of interleukin-10 production  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  positive regulation of mast cell cytokine production  Fc-epsilon receptor I complex  negative regulation of mast cell apoptotic process  Fc-gamma receptor signaling pathway  Fc-epsilon receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I  defense response to bacterium  positive regulation of mast cell degranulation  innate immune response  mast cell activation  positive regulation of phagocytosis  leukocyte migration  cellular response to low-density lipoprotein particle stimulus  protein localization to plasma membrane  
Ontology : EGO-EBIpositive regulation of type IIa hypersensitivity  positive regulation of type III hypersensitivity  positive regulation of type I hypersensitivity  stimulatory C-type lectin receptor signaling pathway  neutrophil activation involved in immune response  T cell differentiation involved in immune response  Fc receptor mediated stimulatory signaling pathway  serotonin secretion by platelet  protein binding  plasma membrane  integral component of plasma membrane  phagocytosis, engulfment  integrin-mediated signaling pathway  blood coagulation  external side of plasma membrane  cell surface  regulation of platelet activation  immunoglobulin mediated immune response  IgE receptor activity  IgE binding  IgG binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  platelet activation  neutrophil chemotaxis  receptor internalization  positive regulation of interleukin-10 production  positive regulation of interleukin-6 production  positive regulation of tumor necrosis factor production  positive regulation of mast cell cytokine production  Fc-epsilon receptor I complex  negative regulation of mast cell apoptotic process  Fc-gamma receptor signaling pathway  Fc-epsilon receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I  defense response to bacterium  positive regulation of mast cell degranulation  innate immune response  mast cell activation  positive regulation of phagocytosis  leukocyte migration  cellular response to low-density lipoprotein particle stimulus  protein localization to plasma membrane  
Pathways : BIOCARTAFc Epsilon Receptor I Signaling in Mast Cells [Genes]   
Pathways : KEGGNatural killer cell mediated cytotoxicity    Fc epsilon RI signaling pathway    Tuberculosis    Asthma   
NDEx NetworkFCER1G
Atlas of Cancer Signalling NetworkFCER1G
Wikipedia pathwaysFCER1G
Orthology - Evolution
OrthoDB2207
GeneTree (enSembl)ENSG00000158869
Phylogenetic Trees/Animal Genes : TreeFamFCER1G
HOVERGENP30273
HOGENOMP30273
Homologs : HomoloGeneFCER1G
Homology/Alignments : Family Browser (UCSC)FCER1G
Gene fusions - Rearrangements
Fusion : MitelmanPTPRJ/FCER1G [11p11.2/1q23.3]  [t(1;11)(q23;p11)]  
Fusion: TCGAPTPRJ 11p11.2 FCER1G 1q23.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCER1G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCER1G
dbVarFCER1G
ClinVarFCER1G
1000_GenomesFCER1G 
Exome Variant ServerFCER1G
ExAC (Exome Aggregation Consortium)FCER1G (select the gene name)
Genetic variants : HAPMAP2207
Genomic Variants (DGV)FCER1G [DGVbeta]
DECIPHER (Syndromes)1:161185087-161189038  ENSG00000158869
CONAN: Copy Number AnalysisFCER1G 
Mutations
ICGC Data PortalFCER1G 
TCGA Data PortalFCER1G 
Broad Tumor PortalFCER1G
OASIS PortalFCER1G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCER1G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCER1G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCER1G
DgiDB (Drug Gene Interaction Database)FCER1G
DoCM (Curated mutations)FCER1G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCER1G (select a term)
intoGenFCER1G
Cancer3DFCER1G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147139   
Orphanet
MedgenFCER1G
Genetic Testing Registry FCER1G
NextProtP30273 [Medical]
TSGene2207
GENETestsFCER1G
Huge Navigator FCER1G [HugePedia]
snp3D : Map Gene to Disease2207
BioCentury BCIQFCER1G
ClinGenFCER1G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2207
Chemical/Pharm GKB GenePA28057
Clinical trialFCER1G
Miscellaneous
canSAR (ICR)FCER1G (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCER1G
EVEXFCER1G
GoPubMedFCER1G
iHOPFCER1G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:05:53 CET 2017

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