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FCGR1A (Fc fragment of IgG receptor Ia)

Identity

Alias_namesFc fragment of IgG, high affinity Ia, receptor for (CD64)
Fc fragment of IgG, high affinity Ia, receptor (CD64)
Alias_symbol (synonym)CD64
CD64A
Other aliasFCRI
IGFR1
HGNC (Hugo) FCGR1A
LocusID (NCBI) 2209
Atlas_Id 53298
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149754250 and ends at 149764074 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCGR1A   3613
LRG (Locus Reference Genomic)LRG_59
Cards
Entrez_Gene (NCBI)FCGR1A  2209  Fc fragment of IgG receptor Ia
AliasesCD64; CD64A; FCRI; IGFR1
GeneCards (Weizmann)FCGR1A
Ensembl hg19 (Hinxton)ENSG00000150337 [Gene_View]  chr1:149754250-149764074 [Contig_View]  FCGR1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000150337 [Gene_View]  chr1:149754250-149764074 [Contig_View]  FCGR1A [Vega]
ICGC DataPortalENSG00000150337
TCGA cBioPortalFCGR1A
AceView (NCBI)FCGR1A
Genatlas (Paris)FCGR1A
WikiGenes2209
SOURCE (Princeton)FCGR1A
Genetics Home Reference (NIH)FCGR1A
Genomic and cartography
GoldenPath hg19 (UCSC)FCGR1A  -     chr1:149754250-149764074 +  1q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FCGR1A  -     1q21.2   [Description]    (hg38-Dec_2013)
EnsemblFCGR1A - 1q21.2 [CytoView hg19]  FCGR1A - 1q21.2 [CytoView hg38]
Mapping of homologs : NCBIFCGR1A [Mapview hg19]  FCGR1A [Mapview hg38]
OMIM146760   
Gene and transcription
Genbank (Entrez)AK291451 AK291502 BC032634 BC152383 DC320241
RefSeq transcript (Entrez)NM_000566
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_007578 NG_033089 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)FCGR1A
Cluster EST : UnigeneHs.77424 [ NCBI ]
CGAP (NCI)Hs.77424
Alternative Splicing GalleryENSG00000150337
Gene ExpressionFCGR1A [ NCBI-GEO ]   FCGR1A [ EBI - ARRAY_EXPRESS ]   FCGR1A [ SEEK ]   FCGR1A [ MEM ]
Gene Expression Viewer (FireBrowse)FCGR1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2209
GTEX Portal (Tissue expression)FCGR1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12314   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12314  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12314
Splice isoforms : SwissVarP12314
PhosPhoSitePlusP12314
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)    Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam00047    pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)FCGR1A
DMDM Disease mutations2209
Blocks (Seattle)FCGR1A
PDB (SRS)3RJD    4W4O    4X4M    4ZNE   
PDB (PDBSum)3RJD    4W4O    4X4M    4ZNE   
PDB (IMB)3RJD    4W4O    4X4M    4ZNE   
PDB (RSDB)3RJD    4W4O    4X4M    4ZNE   
Structural Biology KnowledgeBase3RJD    4W4O    4X4M    4ZNE   
SCOP (Structural Classification of Proteins)3RJD    4W4O    4X4M    4ZNE   
CATH (Classification of proteins structures)3RJD    4W4O    4X4M    4ZNE   
SuperfamilyP12314
Human Protein AtlasENSG00000150337
Peptide AtlasP12314
HPRD00904
IPIIPI00023502   IPI00375293   
Protein Interaction databases
DIP (DOE-UCLA)P12314
IntAct (EBI)P12314
FunCoupENSG00000150337
BioGRIDFCGR1A
STRING (EMBL)FCGR1A
ZODIACFCGR1A
Ontologies - Pathways
QuickGOP12314
Ontology : AmiGOantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  receptor signaling protein activity  protein binding  plasma membrane  plasma membrane  receptor-mediated endocytosis  phagocytosis, engulfment  immune response  signal transduction  integral component of membrane  IgG binding  clathrin-coated endocytic vesicle membrane  early endosome membrane  Fc-gamma receptor signaling pathway involved in phagocytosis  regulation of immune response  interferon-gamma-mediated signaling pathway  
Ontology : EGO-EBIantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  receptor signaling protein activity  protein binding  plasma membrane  plasma membrane  receptor-mediated endocytosis  phagocytosis, engulfment  immune response  signal transduction  integral component of membrane  IgG binding  clathrin-coated endocytic vesicle membrane  early endosome membrane  Fc-gamma receptor signaling pathway involved in phagocytosis  regulation of immune response  interferon-gamma-mediated signaling pathway  
Pathways : KEGGPhagosome    Osteoclast differentiation    Hematopoietic cell lineage    Fc gamma R-mediated phagocytosis    Leishmaniasis    Staphylococcus aureus infection    Tuberculosis    Transcriptional misregulation in cancer    Systemic lupus erythematosus   
NDEx NetworkFCGR1A
Atlas of Cancer Signalling NetworkFCGR1A
Wikipedia pathwaysFCGR1A
Orthology - Evolution
OrthoDB2209
GeneTree (enSembl)ENSG00000150337
Phylogenetic Trees/Animal Genes : TreeFamFCGR1A
HOVERGENP12314
HOGENOMP12314
Homologs : HomoloGeneFCGR1A
Homology/Alignments : Family Browser (UCSC)FCGR1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCGR1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCGR1A
dbVarFCGR1A
ClinVarFCGR1A
1000_GenomesFCGR1A 
Exome Variant ServerFCGR1A
ExAC (Exome Aggregation Consortium)FCGR1A (select the gene name)
Genetic variants : HAPMAP2209
Genomic Variants (DGV)FCGR1A [DGVbeta]
DECIPHER (Syndromes)1:149754250-149764074  ENSG00000150337
CONAN: Copy Number AnalysisFCGR1A 
Mutations
ICGC Data PortalFCGR1A 
TCGA Data PortalFCGR1A 
Broad Tumor PortalFCGR1A
OASIS PortalFCGR1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCGR1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCGR1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCGR1A
DgiDB (Drug Gene Interaction Database)FCGR1A
DoCM (Curated mutations)FCGR1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCGR1A (select a term)
intoGenFCGR1A
Cancer3DFCGR1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146760   
Orphanet
MedgenFCGR1A
Genetic Testing Registry FCGR1A
NextProtP12314 [Medical]
TSGene2209
GENETestsFCGR1A
Huge Navigator FCGR1A [HugePedia]
snp3D : Map Gene to Disease2209
BioCentury BCIQFCGR1A
ClinGenFCGR1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2209
Chemical/Pharm GKB GenePA28060
Clinical trialFCGR1A
Miscellaneous
canSAR (ICR)FCGR1A (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCGR1A
EVEXFCGR1A
GoPubMedFCGR1A
iHOPFCGR1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:01:04 CEST 2017

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