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FCGR3B (Fc fragment of IgG receptor IIIb)

Identity

Alias_namesFCGR3
FCG3
Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Alias_symbol (synonym)CD16
CD16b
Other aliasFCR-10
FCRIII
FCRIIIb
HGNC (Hugo) FCGR3B
LocusID (NCBI) 2215
Atlas_Id 46575
Location 1q23.3  [Link to chromosome band 1q23]
Location_base_pair Starts at 161623198 and ends at 161631963 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCGR3B   3620
Cards
Entrez_Gene (NCBI)FCGR3B  2215  Fc fragment of IgG receptor IIIb
AliasesCD16; CD16b; FCG3; FCGR3; 
FCR-10; FCRIII; FCRIIIb
GeneCards (Weizmann)FCGR3B
Ensembl hg19 (Hinxton)ENSG00000162747 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162747 [Gene_View]  chr1:161623198-161631963 [Contig_View]  FCGR3B [Vega]
ICGC DataPortalENSG00000162747
TCGA cBioPortalFCGR3B
AceView (NCBI)FCGR3B
Genatlas (Paris)FCGR3B
WikiGenes2215
SOURCE (Princeton)FCGR3B
Genetics Home Reference (NIH)FCGR3B
Genomic and cartography
GoldenPath hg38 (UCSC)FCGR3B  -     chr1:161623198-161631963 -  1q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCGR3B  -     1q23.3   [Description]    (hg19-Feb_2009)
EnsemblFCGR3B - 1q23.3 [CytoView hg19]  FCGR3B - 1q23.3 [CytoView hg38]
Mapping of homologs : NCBIFCGR3B [Mapview hg19]  FCGR3B [Mapview hg38]
OMIM610665   
Gene and transcription
Genbank (Entrez)AB025256 AJ581669 AK313219 AK316565 BC128562
RefSeq transcript (Entrez)NM_000570 NM_001244753 NM_001271035 NM_001271036 NM_001271037
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCGR3B
Cluster EST : UnigeneHs.736230 [ NCBI ]
CGAP (NCI)Hs.736230
Alternative Splicing GalleryENSG00000162747
Gene ExpressionFCGR3B [ NCBI-GEO ]   FCGR3B [ EBI - ARRAY_EXPRESS ]   FCGR3B [ SEEK ]   FCGR3B [ MEM ]
Gene Expression Viewer (FireBrowse)FCGR3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2215
GTEX Portal (Tissue expression)FCGR3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75015   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75015  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75015
Splice isoforms : SwissVarO75015
PhosPhoSitePlusO75015
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub   
Domain families : Pfam (Sanger)Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)FCGR3B
DMDM Disease mutations2215
Blocks (Seattle)FCGR3B
PDB (SRS)1E4J    1E4K    1FNL    1T83    1T89   
PDB (PDBSum)1E4J    1E4K    1FNL    1T83    1T89   
PDB (IMB)1E4J    1E4K    1FNL    1T83    1T89   
PDB (RSDB)1E4J    1E4K    1FNL    1T83    1T89   
Structural Biology KnowledgeBase1E4J    1E4K    1FNL    1T83    1T89   
SCOP (Structural Classification of Proteins)1E4J    1E4K    1FNL    1T83    1T89   
CATH (Classification of proteins structures)1E4J    1E4K    1FNL    1T83    1T89   
SuperfamilyO75015
Human Protein AtlasENSG00000162747
Peptide AtlasO75015
HPRD09951
IPIIPI00795501   IPI00023858   IPI01009471   IPI00975801   
Protein Interaction databases
DIP (DOE-UCLA)O75015
IntAct (EBI)O75015
FunCoupENSG00000162747
BioGRIDFCGR3B
STRING (EMBL)FCGR3B
ZODIACFCGR3B
Ontologies - Pathways
QuickGOO75015
Ontology : AmiGOextracellular region  plasma membrane  C-terminal protein lipidation  immune response  IgG binding  secretory granule membrane  anchored component of membrane  neutrophil degranulation  extracellular exosome  
Ontology : EGO-EBIextracellular region  plasma membrane  C-terminal protein lipidation  immune response  IgG binding  secretory granule membrane  anchored component of membrane  neutrophil degranulation  extracellular exosome  
Pathways : KEGGPhagosome    Osteoclast differentiation    Natural killer cell mediated cytotoxicity    Leishmaniasis    Staphylococcus aureus infection    Tuberculosis    Systemic lupus erythematosus   
NDEx NetworkFCGR3B
Atlas of Cancer Signalling NetworkFCGR3B
Wikipedia pathwaysFCGR3B
Orthology - Evolution
OrthoDB2215
GeneTree (enSembl)ENSG00000162747
Phylogenetic Trees/Animal Genes : TreeFamFCGR3B
HOVERGENO75015
HOGENOMO75015
Homologs : HomoloGeneFCGR3B
Homology/Alignments : Family Browser (UCSC)FCGR3B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCGR3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCGR3B
dbVarFCGR3B
ClinVarFCGR3B
1000_GenomesFCGR3B 
Exome Variant ServerFCGR3B
ExAC (Exome Aggregation Consortium)FCGR3B (select the gene name)
Genetic variants : HAPMAP2215
Genomic Variants (DGV)FCGR3B [DGVbeta]
DECIPHERFCGR3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCGR3B 
Mutations
ICGC Data PortalFCGR3B 
TCGA Data PortalFCGR3B 
Broad Tumor PortalFCGR3B
OASIS PortalFCGR3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCGR3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCGR3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCGR3B
DgiDB (Drug Gene Interaction Database)FCGR3B
DoCM (Curated mutations)FCGR3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCGR3B (select a term)
intoGenFCGR3B
Cancer3DFCGR3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610665   
Orphanet
MedgenFCGR3B
Genetic Testing Registry FCGR3B
NextProtO75015 [Medical]
TSGene2215
GENETestsFCGR3B
Huge Navigator FCGR3B [HugePedia]
snp3D : Map Gene to Disease2215
BioCentury BCIQFCGR3B
ClinGenFCGR3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2215
Chemical/Pharm GKB GenePA28066
Clinical trialFCGR3B
Miscellaneous
canSAR (ICR)FCGR3B (select the gene name)
Probes
Litterature
PubMed184 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCGR3B
EVEXFCGR3B
GoPubMedFCGR3B
iHOPFCGR3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:15:46 CEST 2017

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