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FCHO1 (FCH and mu domain containing endocytic adaptor 1)

Identity

Alias (NCBI)-
HGNC (Hugo) FCHO1
HGNC Alias symbKIAA0290
HGNC Previous nameFCH domain only 1
LocusID (NCBI) 23149
Atlas_Id 54316
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 17751477 and ends at 17788561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IL4R (16p12.1) / FCHO1 (19p13.11)MYO9B (19p13.11) / FCHO1 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  MYO9B/FCHO1 (19p13)


External links

Nomenclature
HGNC (Hugo)FCHO1   29002
Cards
Entrez_Gene (NCBI)FCHO1  23149  FCH and mu domain containing endocytic adaptor 1
Aliases
GeneCards (Weizmann)FCHO1
Ensembl hg19 (Hinxton)ENSG00000130475 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130475 [Gene_View]  ENSG00000130475 [Sequence]  chr19:17751477-17788561 [Contig_View]  FCHO1 [Vega]
ICGC DataPortalENSG00000130475
TCGA cBioPortalFCHO1
AceView (NCBI)FCHO1
Genatlas (Paris)FCHO1
WikiGenes23149
SOURCE (Princeton)FCHO1
Genetics Home Reference (NIH)FCHO1
Genomic and cartography
GoldenPath hg38 (UCSC)FCHO1  -     chr19:17751477-17788561 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCHO1  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathFCHO1 - 19p13.11 [CytoView hg19]  FCHO1 - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000130475
genome Data Viewer NCBIFCHO1 [Mapview hg19]  
OMIM613437   
Gene and transcription
Genbank (Entrez)AB006628 AK291410 AK303623 AK309403 AK316458
RefSeq transcript (Entrez)NM_001161357 NM_001161358 NM_001161359 NM_001384370 NM_001384371 NM_001384372 NM_001384373 NM_001384374 NM_001384375 NM_001384376 NM_001384377 NM_001384378 NM_001384379 NM_001384380 NM_001384381 NM_001384384 NM_001384385 NM_001384386 NM_001384387 NM_001384388 NM_001384389 NM_001384390 NM_001384391 NM_001384392 NM_001384393 NM_001384394 NM_001384395 NM_001384396 NM_001384397 NM_001384398 NM_001384399 NM_001384400 NM_001384401 NM_001384402 NM_001384403 NM_001384404 NM_001384405 NM_001384406 NM_001384407 NM_015122
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCHO1
Alternative Splicing GalleryENSG00000130475
Gene ExpressionFCHO1 [ NCBI-GEO ]   FCHO1 [ EBI - ARRAY_EXPRESS ]   FCHO1 [ SEEK ]   FCHO1 [ MEM ]
Gene Expression Viewer (FireBrowse)FCHO1 [ Firebrowse - Broad ]
GenevisibleExpression of FCHO1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23149
GTEX Portal (Tissue expression)FCHO1
Human Protein AtlasENSG00000130475-FCHO1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14526   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14526  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14526
Splice isoforms : SwissVarO14526
PhosPhoSitePlusO14526
Domaine pattern : Prosite (Expaxy)F_BAR (PS51741)    MHD (PS51072)   
Domains : Interpro (EBI)AH/BAR_dom_sf    F_BAR    FCH_dom    FCHo1    FCHo1_F-BAR    MHD    Muniscin_C   
Domain families : Pfam (Sanger)FCH (PF00611)    muHD (PF10291)   
Domain families : Pfam (NCBI)pfam00611    pfam10291   
Domain families : Smart (EMBL)FCH (SM00055)  
Conserved Domain (NCBI)FCHO1
DMDM Disease mutations23149
Blocks (Seattle)FCHO1
SuperfamilyO14526
Human Protein Atlas [tissue]ENSG00000130475-FCHO1 [tissue]
Peptide AtlasO14526
HPRD16887
IPIIPI00182164   IPI00642769   IPI00930746   
Protein Interaction databases
DIP (DOE-UCLA)O14526
IntAct (EBI)O14526
FunCoupENSG00000130475
BioGRIDFCHO1
STRING (EMBL)FCHO1
ZODIACFCHO1
Ontologies - Pathways
QuickGOO14526
Ontology : AmiGOprotein binding  nucleoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  plasma membrane  plasma membrane  clathrin-coated pit  clathrin-coated pit  cytoskeletal protein binding  clathrin-coated vesicle  clathrin-coated vesicle  AP-2 adaptor complex binding  clathrin coat assembly  clathrin coat assembly  membrane organization  clathrin-dependent endocytosis  clathrin-dependent endocytosis  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  plasma membrane  plasma membrane  clathrin-coated pit  clathrin-coated pit  cytoskeletal protein binding  clathrin-coated vesicle  clathrin-coated vesicle  AP-2 adaptor complex binding  clathrin coat assembly  clathrin coat assembly  membrane organization  clathrin-dependent endocytosis  clathrin-dependent endocytosis  
NDEx NetworkFCHO1
Atlas of Cancer Signalling NetworkFCHO1
Wikipedia pathwaysFCHO1
Orthology - Evolution
OrthoDB23149
GeneTree (enSembl)ENSG00000130475
Phylogenetic Trees/Animal Genes : TreeFamFCHO1
HOGENOMO14526
Homologs : HomoloGeneFCHO1
Homology/Alignments : Family Browser (UCSC)FCHO1
Gene fusions - Rearrangements
Fusion : MitelmanMYO9B/FCHO1 [19p13.11/19p13.11]  
Fusion : QuiverFCHO1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCHO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCHO1
dbVarFCHO1
ClinVarFCHO1
1000_GenomesFCHO1 
Exome Variant ServerFCHO1
GNOMAD BrowserENSG00000130475
Varsome BrowserFCHO1
Genetic variants : HAPMAP23149
Genomic Variants (DGV)FCHO1 [DGVbeta]
DECIPHERFCHO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCHO1 
Mutations
ICGC Data PortalFCHO1 
TCGA Data PortalFCHO1 
Broad Tumor PortalFCHO1
OASIS PortalFCHO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCHO1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFCHO1
Mutations and Diseases : HGMDFCHO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCHO1
DgiDB (Drug Gene Interaction Database)FCHO1
DoCM (Curated mutations)FCHO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCHO1 (select a term)
intoGenFCHO1
Cancer3DFCHO1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613437   
Orphanet
DisGeNETFCHO1
MedgenFCHO1
Genetic Testing Registry FCHO1
NextProtO14526 [Medical]
TSGene23149
GENETestsFCHO1
Target ValidationFCHO1
Huge Navigator FCHO1 [HugePedia]
snp3D : Map Gene to Disease23149
BioCentury BCIQFCHO1
ClinGenFCHO1
Clinical trials, drugs, therapy
Protein Interactions : CTD23149
Pharm GKB GenePA134870625
Clinical trialFCHO1
Miscellaneous
canSAR (ICR)FCHO1 (select the gene name)
HarmonizomeFCHO1
DataMed IndexFCHO1
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCHO1
EVEXFCHO1
GoPubMedFCHO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:13:14 CEST 2020

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