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FCN3 (ficolin 3)

Identity

Alias_namesficolin (collagen/fibrinogen domain-containing) 3 (Hakata antigen)
ficolin (collagen/fibrinogen domain containing) 3
Alias_symbol (synonym)FCNH
HAKA1
Other alias
HGNC (Hugo) FCN3
LocusID (NCBI) 8547
Atlas_Id 53622
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 27369110 and ends at 27374852 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF4E3 (3p13) / FCN3 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCN3   3625
LRG (Locus Reference Genomic)LRG_171
Cards
Entrez_Gene (NCBI)FCN3  8547  ficolin 3
AliasesFCNH; HAKA1
GeneCards (Weizmann)FCN3
Ensembl hg19 (Hinxton)ENSG00000142748 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142748 [Gene_View]  chr1:27369110-27374852 [Contig_View]  FCN3 [Vega]
ICGC DataPortalENSG00000142748
TCGA cBioPortalFCN3
AceView (NCBI)FCN3
Genatlas (Paris)FCN3
WikiGenes8547
SOURCE (Princeton)FCN3
Genetics Home Reference (NIH)FCN3
Genomic and cartography
GoldenPath hg38 (UCSC)FCN3  -     chr1:27369110-27374852 -  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCN3  -     1p36.11   [Description]    (hg19-Feb_2009)
EnsemblFCN3 - 1p36.11 [CytoView hg19]  FCN3 - 1p36.11 [CytoView hg38]
Mapping of homologs : NCBIFCN3 [Mapview hg19]  FCN3 [Mapview hg38]
OMIM604973   613860   
Gene and transcription
Genbank (Entrez)AK075140 AK309540 AK309576 AY358081 AY358283
RefSeq transcript (Entrez)NM_003665 NM_173452
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCN3
Cluster EST : UnigeneHs.333383 [ NCBI ]
CGAP (NCI)Hs.333383
Alternative Splicing GalleryENSG00000142748
Gene ExpressionFCN3 [ NCBI-GEO ]   FCN3 [ EBI - ARRAY_EXPRESS ]   FCN3 [ SEEK ]   FCN3 [ MEM ]
Gene Expression Viewer (FireBrowse)FCN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8547
GTEX Portal (Tissue expression)FCN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75636   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75636  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75636
Splice isoforms : SwissVarO75636
PhosPhoSitePlusO75636
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)Fibrinogen_a/b/g_C_1    Fibrinogen_a/b/g_C_2    Fibrinogen_a/b/g_C_dom    Fibrinogen_CS   
Domain families : Pfam (Sanger)Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
Conserved Domain (NCBI)FCN3
DMDM Disease mutations8547
Blocks (Seattle)FCN3
PDB (SRS)1LA5    2J5Z    2J60    2J64   
PDB (PDBSum)1LA5    2J5Z    2J60    2J64   
PDB (IMB)1LA5    2J5Z    2J60    2J64   
PDB (RSDB)1LA5    2J5Z    2J60    2J64   
Structural Biology KnowledgeBase1LA5    2J5Z    2J60    2J64   
SCOP (Structural Classification of Proteins)1LA5    2J5Z    2J60    2J64   
CATH (Classification of proteins structures)1LA5    2J5Z    2J60    2J64   
SuperfamilyO75636
Human Protein AtlasENSG00000142748
Peptide AtlasO75636
HPRD05399
IPIIPI00293925   IPI00419744   IPI00945343   
Protein Interaction databases
DIP (DOE-UCLA)O75636
IntAct (EBI)O75636
FunCoupENSG00000142748
BioGRIDFCN3
STRING (EMBL)FCN3
ZODIACFCN3
Ontologies - Pathways
QuickGOO75636
Ontology : AmiGOcomplement activation, lectin pathway  complement activation, lectin pathway  antigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  collagen trimer  proteolysis  complement activation  complement activation  carbohydrate binding  recognition of apoptotic cell  negative regulation of viral entry into host cell  metal ion binding  defense response to virus  blood microparticle  negative regulation of RNA biosynthetic process  
Ontology : EGO-EBIcomplement activation, lectin pathway  complement activation, lectin pathway  antigen binding  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  collagen trimer  proteolysis  complement activation  complement activation  carbohydrate binding  recognition of apoptotic cell  negative regulation of viral entry into host cell  metal ion binding  defense response to virus  blood microparticle  negative regulation of RNA biosynthetic process  
NDEx NetworkFCN3
Atlas of Cancer Signalling NetworkFCN3
Wikipedia pathwaysFCN3
Orthology - Evolution
OrthoDB8547
GeneTree (enSembl)ENSG00000142748
Phylogenetic Trees/Animal Genes : TreeFamFCN3
HOVERGENO75636
HOGENOMO75636
Homologs : HomoloGeneFCN3
Homology/Alignments : Family Browser (UCSC)FCN3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCN3
dbVarFCN3
ClinVarFCN3
1000_GenomesFCN3 
Exome Variant ServerFCN3
ExAC (Exome Aggregation Consortium)FCN3 (select the gene name)
Genetic variants : HAPMAP8547
Genomic Variants (DGV)FCN3 [DGVbeta]
DECIPHERFCN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCN3 
Mutations
ICGC Data PortalFCN3 
TCGA Data PortalFCN3 
Broad Tumor PortalFCN3
OASIS PortalFCN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch FCN3
DgiDB (Drug Gene Interaction Database)FCN3
DoCM (Curated mutations)FCN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCN3 (select a term)
intoGenFCN3
Cancer3DFCN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604973    613860   
Orphanet21995   
MedgenFCN3
Genetic Testing Registry FCN3
NextProtO75636 [Medical]
TSGene8547
GENETestsFCN3
Target ValidationFCN3
Huge Navigator FCN3 [HugePedia]
snp3D : Map Gene to Disease8547
BioCentury BCIQFCN3
ClinGenFCN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8547
Chemical/Pharm GKB GenePA28071
Clinical trialFCN3
Miscellaneous
canSAR (ICR)FCN3 (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCN3
EVEXFCN3
GoPubMedFCN3
iHOPFCN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:53:20 CEST 2017

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