FCRL2 (Fc receptor like 2)

2008-08-01  

Identity

HGNC
FCRL2
LOCATION
1q23.1
LOCUSID
79368
ALIAS
CD307b,FCRH2,IFGP4,IRTA4,SPAP1,SPAP1A,SPAP1B,SPAP1C

Other Information

Locus ID:

NCBI: 79368
MIM: 606509
HGNC: 14875
Ensembl: ENSG00000132704

Variants:

dbSNP: 79368
ClinVar: 79368
TCGA: ENSG00000132704
COSMIC: FCRL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132704ENST00000361516Q96LA5
ENSG00000132704ENST00000368181Q96LA5
ENSG00000132704ENST00000469986Q96LA5

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
183144422008FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia.20
210684052010FcR-like 2 Inhibition of B cell receptor-mediated activation of B cells.17
187049342008Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.11
188026952009Low representation of Fc receptor-like 1-5 molecules in leukemic cells from Iranian patients with acute lymphoblastic leukemia.5
257389962015Expression Profile of Human Fc Receptor-Like 1, 2, and 4 Molecules in Peripheral Blood Mononuclear Cells of Patients with Hashimoto's Thyroiditis and Graves' Disease.4
196823112009FCRL2 mRNA expression is inversely associated with clinical progression in chronic lymphocytic leukemia.3
271934702016Investigation of the human FCRL1, 2, and 4 gene expressions in patients with rheumatoid arthritis.2
310928132019Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status.1

Citation

Dessen P

FCRL2 (Fc receptor like 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50298/fcrl2