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FCRL3 (Fc receptor like 3)

Identity

Alias_namesFc receptor-like 3
Alias_symbol (synonym)FCRH3
IRTA3
IFGP3
SPAP2a
SPAP2
SPAP2b
SPAP2c
SPAP2d
SPAP2e
CD307c
Other alias
HGNC (Hugo) FCRL3
LocusID (NCBI) 115352
Atlas_Id 50413
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 157678188 and ends at 157700857 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FCRL3   18506
Cards
Entrez_Gene (NCBI)FCRL3  115352  Fc receptor like 3
AliasesCD307c; FCRH3; IFGP3; IRTA3; 
SPAP2
GeneCards (Weizmann)FCRL3
Ensembl hg19 (Hinxton)ENSG00000160856 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160856 [Gene_View]  ENSG00000160856 [Sequence]  chr1:157678188-157700857 [Contig_View]  FCRL3 [Vega]
ICGC DataPortalENSG00000160856
TCGA cBioPortalFCRL3
AceView (NCBI)FCRL3
Genatlas (Paris)FCRL3
WikiGenes115352
SOURCE (Princeton)FCRL3
Genetics Home Reference (NIH)FCRL3
Genomic and cartography
GoldenPath hg38 (UCSC)FCRL3  -     chr1:157678188-157700857 -  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCRL3  -     1q23.1   [Description]    (hg19-Feb_2009)
EnsemblFCRL3 - 1q23.1 [CytoView hg19]  FCRL3 - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBIFCRL3 [Mapview hg19]  FCRL3 [Mapview hg38]
OMIM606510   
Gene and transcription
Genbank (Entrez)AF416901 AF416902 AF416903 AF416904 AF416905
RefSeq transcript (Entrez)NM_001024667 NM_001320333 NM_052939
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCRL3
Cluster EST : UnigeneHs.292449 [ NCBI ]
CGAP (NCI)Hs.292449
Alternative Splicing GalleryENSG00000160856
Gene ExpressionFCRL3 [ NCBI-GEO ]   FCRL3 [ EBI - ARRAY_EXPRESS ]   FCRL3 [ SEEK ]   FCRL3 [ MEM ]
Gene Expression Viewer (FireBrowse)FCRL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115352
GTEX Portal (Tissue expression)FCRL3
Human Protein AtlasENSG00000160856-FCRL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96P31   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96P31  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96P31
Splice isoforms : SwissVarQ96P31
PhosPhoSitePlusQ96P31
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_sub2    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)    Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam00047    pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)FCRL3
DMDM Disease mutations115352
Blocks (Seattle)FCRL3
SuperfamilyQ96P31
Human Protein Atlas [tissue]ENSG00000160856-FCRL3 [tissue]
Peptide AtlasQ96P31
HPRD07352
IPIIPI00644700   IPI00890774   IPI00890763   IPI00890834   IPI00867538   IPI00171151   IPI00643080   
Protein Interaction databases
DIP (DOE-UCLA)Q96P31
IntAct (EBI)Q96P31
FunCoupENSG00000160856
BioGRIDFCRL3
STRING (EMBL)FCRL3
ZODIACFCRL3
Ontologies - Pathways
QuickGOQ96P31
Ontology : AmiGOnegative regulation of immunoglobulin production  plasma membrane  cell surface  integral component of membrane  kinase binding  phosphatase binding  protein phosphatase binding  positive regulation of B cell proliferation  regulation of toll-like receptor 9 signaling pathway  positive regulation of MAPK cascade  regulation of B cell differentiation  negative regulation of B cell receptor signaling pathway  regulation of B cell activation  regulation of calcium ion import  positive regulation of protein serine/threonine phosphatase activity  protein tyrosine kinase binding  
Ontology : EGO-EBInegative regulation of immunoglobulin production  plasma membrane  cell surface  integral component of membrane  kinase binding  phosphatase binding  protein phosphatase binding  positive regulation of B cell proliferation  regulation of toll-like receptor 9 signaling pathway  positive regulation of MAPK cascade  regulation of B cell differentiation  negative regulation of B cell receptor signaling pathway  regulation of B cell activation  regulation of calcium ion import  positive regulation of protein serine/threonine phosphatase activity  protein tyrosine kinase binding  
NDEx NetworkFCRL3
Atlas of Cancer Signalling NetworkFCRL3
Wikipedia pathwaysFCRL3
Orthology - Evolution
OrthoDB115352
GeneTree (enSembl)ENSG00000160856
Phylogenetic Trees/Animal Genes : TreeFamFCRL3
HOVERGENQ96P31
HOGENOMQ96P31
Homologs : HomoloGeneFCRL3
Homology/Alignments : Family Browser (UCSC)FCRL3
Gene fusions - Rearrangements
Fusion : QuiverFCRL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCRL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCRL3
dbVarFCRL3
ClinVarFCRL3
1000_GenomesFCRL3 
Exome Variant ServerFCRL3
ExAC (Exome Aggregation Consortium)ENSG00000160856
GNOMAD BrowserENSG00000160856
Varsome BrowserFCRL3
Genetic variants : HAPMAP115352
Genomic Variants (DGV)FCRL3 [DGVbeta]
DECIPHERFCRL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCRL3 
Mutations
ICGC Data PortalFCRL3 
TCGA Data PortalFCRL3 
Broad Tumor PortalFCRL3
OASIS PortalFCRL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFCRL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCRL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCRL3
DgiDB (Drug Gene Interaction Database)FCRL3
DoCM (Curated mutations)FCRL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCRL3 (select a term)
intoGenFCRL3
Cancer3DFCRL3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606510   
Orphanet
DisGeNETFCRL3
MedgenFCRL3
Genetic Testing Registry FCRL3
NextProtQ96P31 [Medical]
TSGene115352
GENETestsFCRL3
Target ValidationFCRL3
Huge Navigator FCRL3 [HugePedia]
snp3D : Map Gene to Disease115352
BioCentury BCIQFCRL3
ClinGenFCRL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD115352
Chemical/Pharm GKB GenePA142671767
Clinical trialFCRL3
Miscellaneous
canSAR (ICR)FCRL3 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCRL3
EVEXFCRL3
GoPubMedFCRL3
iHOPFCRL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Aug 27 11:22:48 CEST 2018

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