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FCRL4 (Fc receptor like 4)

Identity

Alias_namesFc receptor-like 4
Alias_symbol (synonym)FCRH4
IRTA1
IGFP2
CD307d
Other alias
HGNC (Hugo) FCRL4
LocusID (NCBI) 83417
Atlas_Id 40995
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 157573749 and ends at 157598080 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FCRL4 (1q23.1) / IGH (14q32.33)FCRL4 (1q23.1) / IQGAP3 (1q22)IGH (14q32.33) / FCRL4 (1q23.1)
IGHG1 (14q32.33) / FCRL4 (1q23.1)Ig () / FCRL4 (1q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(1;1)(p36;q21) in Non Hodgkin Lymphoma
t(1;14)(q21;q32) BCL9/IGH::t(1;22)(q21;q11) IGL/BCL9
t(1;14)(q21;q32) FCRL4/IGH
t(1;14)(q21;q32)::t(1;22)(q21;q11)


External links

Nomenclature
HGNC (Hugo)FCRL4   18507
Cards
Entrez_Gene (NCBI)FCRL4  83417  Fc receptor like 4
AliasesCD307d; FCRH4; IGFP2; IRTA1
GeneCards (Weizmann)FCRL4
Ensembl hg19 (Hinxton)ENSG00000163518 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163518 [Gene_View]  chr1:157573749-157598080 [Contig_View]  FCRL4 [Vega]
ICGC DataPortalENSG00000163518
TCGA cBioPortalFCRL4
AceView (NCBI)FCRL4
Genatlas (Paris)FCRL4
WikiGenes83417
SOURCE (Princeton)FCRL4
Genetics Home Reference (NIH)FCRL4
Genomic and cartography
GoldenPath hg38 (UCSC)FCRL4  -     chr1:157573749-157598080 -  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FCRL4  -     1q23.1   [Description]    (hg19-Feb_2009)
EnsemblFCRL4 - 1q23.1 [CytoView hg19]  FCRL4 - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBIFCRL4 [Mapview hg19]  FCRL4 [Mapview hg38]
OMIM605876   
Gene and transcription
Genbank (Entrez)AF329490 AF329492 AF343659 AF343660 AF343661
RefSeq transcript (Entrez)NM_031282
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FCRL4
Cluster EST : UnigeneHs.120260 [ NCBI ]
CGAP (NCI)Hs.120260
Alternative Splicing GalleryENSG00000163518
Gene ExpressionFCRL4 [ NCBI-GEO ]   FCRL4 [ EBI - ARRAY_EXPRESS ]   FCRL4 [ SEEK ]   FCRL4 [ MEM ]
Gene Expression Viewer (FireBrowse)FCRL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83417
GTEX Portal (Tissue expression)FCRL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PJ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PJ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PJ5
Splice isoforms : SwissVarQ96PJ5
PhosPhoSitePlusQ96PJ5
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Immunoglobulin   
Domain families : Pfam (Sanger)ig (PF00047)    Ig_2 (PF13895)   
Domain families : Pfam (NCBI)pfam00047    pfam13895   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)FCRL4
DMDM Disease mutations83417
Blocks (Seattle)FCRL4
SuperfamilyQ96PJ5
Human Protein AtlasENSG00000163518
Peptide AtlasQ96PJ5
HPRD16168
IPIIPI00044510   IPI00890728   
Protein Interaction databases
DIP (DOE-UCLA)Q96PJ5
IntAct (EBI)Q96PJ5
FunCoupENSG00000163518
BioGRIDFCRL4
STRING (EMBL)FCRL4
ZODIACFCRL4
Ontologies - Pathways
QuickGOQ96PJ5
Ontology : AmiGOadaptive immune response  protein binding  plasma membrane  integral component of membrane  extracellular exosome  
Ontology : EGO-EBIadaptive immune response  protein binding  plasma membrane  integral component of membrane  extracellular exosome  
NDEx NetworkFCRL4
Atlas of Cancer Signalling NetworkFCRL4
Wikipedia pathwaysFCRL4
Orthology - Evolution
OrthoDB83417
GeneTree (enSembl)ENSG00000163518
Phylogenetic Trees/Animal Genes : TreeFamFCRL4
HOVERGENQ96PJ5
HOGENOMQ96PJ5
Homologs : HomoloGeneFCRL4
Homology/Alignments : Family Browser (UCSC)FCRL4
Gene fusions - Rearrangements
Fusion : MitelmanFCRL4/IQGAP3 [1q23.1/1q22]  
Fusion : MitelmanIGH/FCRL4 [14q32.33/1q23.1]  [t(1;14)(q23;q32)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFCRL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FCRL4
dbVarFCRL4
ClinVarFCRL4
1000_GenomesFCRL4 
Exome Variant ServerFCRL4
ExAC (Exome Aggregation Consortium)FCRL4 (select the gene name)
Genetic variants : HAPMAP83417
Genomic Variants (DGV)FCRL4 [DGVbeta]
DECIPHERFCRL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFCRL4 
Mutations
ICGC Data PortalFCRL4 
TCGA Data PortalFCRL4 
Broad Tumor PortalFCRL4
OASIS PortalFCRL4 [ Somatic mutations - Copy number]
Cancer Gene: CensusFCRL4 
Somatic Mutations in Cancer : COSMICFCRL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFCRL4
intOGen PortalFCRL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FCRL4
DgiDB (Drug Gene Interaction Database)FCRL4
DoCM (Curated mutations)FCRL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FCRL4 (select a term)
intoGenFCRL4
Cancer3DFCRL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605876   
Orphanet
MedgenFCRL4
Genetic Testing Registry FCRL4
NextProtQ96PJ5 [Medical]
TSGene83417
GENETestsFCRL4
Huge Navigator FCRL4 [HugePedia]
snp3D : Map Gene to Disease83417
BioCentury BCIQFCRL4
ClinGenFCRL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83417
Chemical/Pharm GKB GenePA142671768
Clinical trialFCRL4
Miscellaneous
canSAR (ICR)FCRL4 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFCRL4
EVEXFCRL4
GoPubMedFCRL4
iHOPFCRL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:15:49 CEST 2017

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