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FDX1 (ferredoxin 1)

Identity

Alias_namesFDX
Alias_symbol (synonym)ADX
Other aliasLOH11CR1D
HGNC (Hugo) FDX1
LocusID (NCBI) 2230
Atlas_Id 63352
Location 11q22.3  [Link to chromosome band 11q22]
Location_base_pair Starts at 110429937 and ends at 110464884 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FDX1   3638
Cards
Entrez_Gene (NCBI)FDX1  2230  ferredoxin 1
AliasesADX; FDX; LOH11CR1D
GeneCards (Weizmann)FDX1
Ensembl hg19 (Hinxton)ENSG00000137714 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137714 [Gene_View]  chr11:110429937-110464884 [Contig_View]  FDX1 [Vega]
ICGC DataPortalENSG00000137714
TCGA cBioPortalFDX1
AceView (NCBI)FDX1
Genatlas (Paris)FDX1
WikiGenes2230
SOURCE (Princeton)FDX1
Genetics Home Reference (NIH)FDX1
Genomic and cartography
GoldenPath hg38 (UCSC)FDX1  -     chr11:110429937-110464884 +  11q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FDX1  -     11q22.3   [Description]    (hg19-Feb_2009)
EnsemblFDX1 - 11q22.3 [CytoView hg19]  FDX1 - 11q22.3 [CytoView hg38]
Mapping of homologs : NCBIFDX1 [Mapview hg19]  FDX1 [Mapview hg38]
OMIM103260   
Gene and transcription
Genbank (Entrez)AA505582 AB096243 BC010284 BC017063 BQ650029
RefSeq transcript (Entrez)NM_004109
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FDX1
Cluster EST : UnigeneHs.744 [ NCBI ]
CGAP (NCI)Hs.744
Alternative Splicing GalleryENSG00000137714
Gene ExpressionFDX1 [ NCBI-GEO ]   FDX1 [ EBI - ARRAY_EXPRESS ]   FDX1 [ SEEK ]   FDX1 [ MEM ]
Gene Expression Viewer (FireBrowse)FDX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2230
GTEX Portal (Tissue expression)FDX1
Human Protein AtlasENSG00000137714-FDX1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10109   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10109  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10109
Splice isoforms : SwissVarP10109
PhosPhoSitePlusP10109
Domaine pattern : Prosite (Expaxy)2FE2S_FER_2 (PS51085)    ADX (PS00814)   
Domains : Interpro (EBI)2Fe-2S_ferredoxin-type    Adrenodoxin    Adrenodoxin_Fe-S_BS    Beta-grasp_dom   
Domain families : Pfam (Sanger)Fer2 (PF00111)   
Domain families : Pfam (NCBI)pfam00111   
Conserved Domain (NCBI)FDX1
DMDM Disease mutations2230
Blocks (Seattle)FDX1
PDB (SRS)3N9Y    3N9Z    3NA0    3NA1    3P1M   
PDB (PDBSum)3N9Y    3N9Z    3NA0    3NA1    3P1M   
PDB (IMB)3N9Y    3N9Z    3NA0    3NA1    3P1M   
PDB (RSDB)3N9Y    3N9Z    3NA0    3NA1    3P1M   
Structural Biology KnowledgeBase3N9Y    3N9Z    3NA0    3NA1    3P1M   
SCOP (Structural Classification of Proteins)3N9Y    3N9Z    3NA0    3NA1    3P1M   
CATH (Classification of proteins structures)3N9Y    3N9Z    3NA0    3NA1    3P1M   
SuperfamilyP10109
Human Protein Atlas [tissue]ENSG00000137714-FDX1 [tissue]
Peptide AtlasP10109
HPRD00059
IPIIPI00019326   
Protein Interaction databases
DIP (DOE-UCLA)P10109
IntAct (EBI)P10109
FunCoupENSG00000137714
BioGRIDFDX1
STRING (EMBL)FDX1
ZODIACFDX1
Ontologies - Pathways
QuickGOP10109
Ontology : AmiGOiron ion binding  mitochondrion  mitochondrial matrix  C21-steroid hormone biosynthetic process  cholesterol metabolic process  electron carrier activity  electron carrier activity  sterol metabolic process  hormone biosynthetic process  small molecule metabolic process  2 iron, 2 sulfur cluster binding  oxidation-reduction process  cellular response to cAMP  cellular response to forskolin  
Ontology : EGO-EBIiron ion binding  mitochondrion  mitochondrial matrix  C21-steroid hormone biosynthetic process  cholesterol metabolic process  electron carrier activity  electron carrier activity  sterol metabolic process  hormone biosynthetic process  small molecule metabolic process  2 iron, 2 sulfur cluster binding  oxidation-reduction process  cellular response to cAMP  cellular response to forskolin  
NDEx NetworkFDX1
Atlas of Cancer Signalling NetworkFDX1
Wikipedia pathwaysFDX1
Orthology - Evolution
OrthoDB2230
GeneTree (enSembl)ENSG00000137714
Phylogenetic Trees/Animal Genes : TreeFamFDX1
HOVERGENP10109
HOGENOMP10109
Homologs : HomoloGeneFDX1
Homology/Alignments : Family Browser (UCSC)FDX1
Gene fusions - Rearrangements
Fusion: Tumor Portal FDX1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFDX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FDX1
dbVarFDX1
ClinVarFDX1
1000_GenomesFDX1 
Exome Variant ServerFDX1
ExAC (Exome Aggregation Consortium)ENSG00000137714
GNOMAD BrowserENSG00000137714
Genetic variants : HAPMAP2230
Genomic Variants (DGV)FDX1 [DGVbeta]
DECIPHERFDX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFDX1 
Mutations
ICGC Data PortalFDX1 
TCGA Data PortalFDX1 
Broad Tumor PortalFDX1
OASIS PortalFDX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFDX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFDX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch FDX1
DgiDB (Drug Gene Interaction Database)FDX1
DoCM (Curated mutations)FDX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FDX1 (select a term)
intoGenFDX1
Cancer3DFDX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM103260   
Orphanet
MedgenFDX1
Genetic Testing Registry FDX1
NextProtP10109 [Medical]
TSGene2230
GENETestsFDX1
Target ValidationFDX1
Huge Navigator FDX1 [HugePedia]
snp3D : Map Gene to Disease2230
BioCentury BCIQFDX1
ClinGenFDX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2230
Chemical/Pharm GKB GenePA28082
Clinical trialFDX1
Miscellaneous
canSAR (ICR)FDX1 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFDX1
EVEXFDX1
GoPubMedFDX1
iHOPFDX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:47:39 CET 2017

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