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FFAR2 (free fatty acid receptor 2)

Identity

Alias_namesGPR43
G protein-coupled receptor 43
Alias_symbol (synonym)FFA2R
Other alias
HGNC (Hugo) FFAR2
LocusID (NCBI) 2867
Atlas_Id 52091
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 35449715 and ends at 35451767 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FFAR2   4501
Cards
Entrez_Gene (NCBI)FFAR2  2867  free fatty acid receptor 2
AliasesFFA2R; GPR43
GeneCards (Weizmann)FFAR2
Ensembl hg19 (Hinxton)ENSG00000126262 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126262 [Gene_View]  chr19:35449715-35451767 [Contig_View]  FFAR2 [Vega]
ICGC DataPortalENSG00000126262
TCGA cBioPortalFFAR2
AceView (NCBI)FFAR2
Genatlas (Paris)FFAR2
WikiGenes2867
SOURCE (Princeton)FFAR2
Genetics Home Reference (NIH)FFAR2
Genomic and cartography
GoldenPath hg38 (UCSC)FFAR2  -     chr19:35449715-35451767 +  19q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FFAR2  -     19q13.12   [Description]    (hg19-Feb_2009)
EnsemblFFAR2 - 19q13.12 [CytoView hg19]  FFAR2 - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIFFAR2 [Mapview hg19]  FFAR2 [Mapview hg38]
OMIM603823   
Gene and transcription
Genbank (Entrez)AB378083 AX810701 BC095535 BC096198 BC096199
RefSeq transcript (Entrez)NM_005306
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FFAR2
Cluster EST : UnigeneHs.248056 [ NCBI ]
CGAP (NCI)Hs.248056
Alternative Splicing GalleryENSG00000126262
Gene ExpressionFFAR2 [ NCBI-GEO ]   FFAR2 [ EBI - ARRAY_EXPRESS ]   FFAR2 [ SEEK ]   FFAR2 [ MEM ]
Gene Expression Viewer (FireBrowse)FFAR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2867
GTEX Portal (Tissue expression)FFAR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15552   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15552  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15552
Splice isoforms : SwissVarO15552
PhosPhoSitePlusO15552
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    GPR40-rel_orph   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)FFAR2
DMDM Disease mutations2867
Blocks (Seattle)FFAR2
SuperfamilyO15552
Human Protein AtlasENSG00000126262
Peptide AtlasO15552
HPRD04824
IPIIPI00007366   
Protein Interaction databases
DIP (DOE-UCLA)O15552
IntAct (EBI)O15552
FunCoupENSG00000126262
BioGRIDFFAR2
STRING (EMBL)FFAR2
ZODIACFFAR2
Ontologies - Pathways
QuickGOO15552
Ontology : AmiGOleukocyte chemotaxis involved in inflammatory response  mucosal immune response  regulation of acute inflammatory response  positive regulation of cytokine production involved in immune response  cell surface pattern recognition receptor signaling pathway  positive regulation of acute inflammatory response to non-antigenic stimulus  G-protein coupled receptor activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  lipid binding  lipid storage  positive regulation of chemokine production  glucose homeostasis  cell projection  fat cell differentiation  cellular response to fatty acid  regulation of peptide hormone secretion  positive regulation of interleukin-8 secretion  
Ontology : EGO-EBIleukocyte chemotaxis involved in inflammatory response  mucosal immune response  regulation of acute inflammatory response  positive regulation of cytokine production involved in immune response  cell surface pattern recognition receptor signaling pathway  positive regulation of acute inflammatory response to non-antigenic stimulus  G-protein coupled receptor activity  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  lipid binding  lipid storage  positive regulation of chemokine production  glucose homeostasis  cell projection  fat cell differentiation  cellular response to fatty acid  regulation of peptide hormone secretion  positive regulation of interleukin-8 secretion  
NDEx NetworkFFAR2
Atlas of Cancer Signalling NetworkFFAR2
Wikipedia pathwaysFFAR2
Orthology - Evolution
OrthoDB2867
GeneTree (enSembl)ENSG00000126262
Phylogenetic Trees/Animal Genes : TreeFamFFAR2
HOVERGENO15552
HOGENOMO15552
Homologs : HomoloGeneFFAR2
Homology/Alignments : Family Browser (UCSC)FFAR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFFAR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FFAR2
dbVarFFAR2
ClinVarFFAR2
1000_GenomesFFAR2 
Exome Variant ServerFFAR2
ExAC (Exome Aggregation Consortium)FFAR2 (select the gene name)
Genetic variants : HAPMAP2867
Genomic Variants (DGV)FFAR2 [DGVbeta]
DECIPHERFFAR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFFAR2 
Mutations
ICGC Data PortalFFAR2 
TCGA Data PortalFFAR2 
Broad Tumor PortalFFAR2
OASIS PortalFFAR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFFAR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFFAR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FFAR2
DgiDB (Drug Gene Interaction Database)FFAR2
DoCM (Curated mutations)FFAR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FFAR2 (select a term)
intoGenFFAR2
Cancer3DFFAR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603823   
Orphanet
MedgenFFAR2
Genetic Testing Registry FFAR2
NextProtO15552 [Medical]
TSGene2867
GENETestsFFAR2
Huge Navigator FFAR2 [HugePedia]
snp3D : Map Gene to Disease2867
BioCentury BCIQFFAR2
ClinGenFFAR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2867
Chemical/Pharm GKB GenePA28890
Clinical trialFFAR2
Miscellaneous
canSAR (ICR)FFAR2 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFFAR2
EVEXFFAR2
GoPubMedFFAR2
iHOPFFAR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:15:54 CEST 2017

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