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FFAR4 (free fatty acid receptor 4)

Identity

Alias_namesGPR129
GPR120
O3FAR1
G protein-coupled receptor 129
G protein-coupled receptor 120
omega-3 fatty acid receptor 1
Alias_symbol (synonym)PGR4
Other aliasBMIQ10
GT01
HGNC (Hugo) FFAR4
LocusID (NCBI) 338557
Atlas_Id 53816
Location 10q23.33  [Link to chromosome band 10q23]
Location_base_pair Starts at 95326422 and ends at 95349829 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FFAR4   19061
Cards
Entrez_Gene (NCBI)FFAR4  338557  free fatty acid receptor 4
AliasesBMIQ10; GPR120; GPR129; GT01; 
O3FAR1; PGR4
GeneCards (Weizmann)FFAR4
Ensembl hg19 (Hinxton)ENSG00000186188 [Gene_View]  chr10:95326422-95349829 [Contig_View]  FFAR4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186188 [Gene_View]  chr10:95326422-95349829 [Contig_View]  FFAR4 [Vega]
ICGC DataPortalENSG00000186188
TCGA cBioPortalFFAR4
AceView (NCBI)FFAR4
Genatlas (Paris)FFAR4
WikiGenes338557
SOURCE (Princeton)FFAR4
Genetics Home Reference (NIH)FFAR4
Genomic and cartography
GoldenPath hg19 (UCSC)FFAR4  -     chr10:95326422-95349829 +  10q23.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FFAR4  -     10q23.33   [Description]    (hg38-Dec_2013)
EnsemblFFAR4 - 10q23.33 [CytoView hg19]  FFAR4 - 10q23.33 [CytoView hg38]
Mapping of homologs : NCBIFFAR4 [Mapview hg19]  FFAR4 [Mapview hg38]
OMIM607514   609044   
Gene and transcription
Genbank (Entrez)AB115768 AI469384 AI732606 AK301525 AY255573
RefSeq transcript (Entrez)NM_001195755 NM_181745
RefSeq genomic (Entrez)NC_000010 NC_018921 NG_032670 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)FFAR4
Cluster EST : UnigeneHs.661022 [ NCBI ]
CGAP (NCI)Hs.661022
Alternative Splicing GalleryENSG00000186188
Gene ExpressionFFAR4 [ NCBI-GEO ]   FFAR4 [ EBI - ARRAY_EXPRESS ]   FFAR4 [ SEEK ]   FFAR4 [ MEM ]
Gene Expression Viewer (FireBrowse)FFAR4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)338557
GTEX Portal (Tissue expression)FFAR4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5NUL3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5NUL3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5NUL3
Splice isoforms : SwissVarQ5NUL3
PhosPhoSitePlusQ5NUL3
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)FFAR4
DMDM Disease mutations338557
Blocks (Seattle)FFAR4
SuperfamilyQ5NUL3
Human Protein AtlasENSG00000186188
Peptide AtlasQ5NUL3
HPRD16422
IPIIPI00376213   IPI00383963   
Protein Interaction databases
DIP (DOE-UCLA)Q5NUL3
IntAct (EBI)Q5NUL3
FunCoupENSG00000186188
BioGRIDFFAR4
STRING (EMBL)FFAR4
ZODIACFFAR4
Ontologies - Pathways
QuickGOQ5NUL3
Ontology : AmiGOfatty acid binding  fatty acid binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  regulation of glucose transport  endocytic vesicle  cellular response to hormone stimulus  peptide binding  negative regulation of apoptotic process  fat cell differentiation  hormone secretion  negative regulation of cytokine secretion  negative regulation of inflammatory response  detection of chemical stimulus involved in sensory perception of taste  positive regulation of ERK1 and ERK2 cascade  response to peptide  
Ontology : EGO-EBIfatty acid binding  fatty acid binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  taste receptor activity  regulation of glucose transport  endocytic vesicle  cellular response to hormone stimulus  peptide binding  negative regulation of apoptotic process  fat cell differentiation  hormone secretion  negative regulation of cytokine secretion  negative regulation of inflammatory response  detection of chemical stimulus involved in sensory perception of taste  positive regulation of ERK1 and ERK2 cascade  response to peptide  
NDEx NetworkFFAR4
Atlas of Cancer Signalling NetworkFFAR4
Wikipedia pathwaysFFAR4
Orthology - Evolution
OrthoDB338557
GeneTree (enSembl)ENSG00000186188
Phylogenetic Trees/Animal Genes : TreeFamFFAR4
HOVERGENQ5NUL3
HOGENOMQ5NUL3
Homologs : HomoloGeneFFAR4
Homology/Alignments : Family Browser (UCSC)FFAR4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFFAR4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FFAR4
dbVarFFAR4
ClinVarFFAR4
1000_GenomesFFAR4 
Exome Variant ServerFFAR4
ExAC (Exome Aggregation Consortium)FFAR4 (select the gene name)
Genetic variants : HAPMAP338557
Genomic Variants (DGV)FFAR4 [DGVbeta]
DECIPHER (Syndromes)10:95326422-95349829  ENSG00000186188
CONAN: Copy Number AnalysisFFAR4 
Mutations
ICGC Data PortalFFAR4 
TCGA Data PortalFFAR4 
Broad Tumor PortalFFAR4
OASIS PortalFFAR4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDFFAR4
BioMutasearch FFAR4
DgiDB (Drug Gene Interaction Database)FFAR4
DoCM (Curated mutations)FFAR4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FFAR4 (select a term)
intoGenFFAR4
Cancer3DFFAR4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607514    609044   
Orphanet
MedgenFFAR4
Genetic Testing Registry FFAR4
NextProtQ5NUL3 [Medical]
TSGene338557
GENETestsFFAR4
Huge Navigator FFAR4 [HugePedia]
snp3D : Map Gene to Disease338557
BioCentury BCIQFFAR4
ClinGenFFAR4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD338557
Chemical/Pharm GKB GenePA134924595
Clinical trialFFAR4
Miscellaneous
canSAR (ICR)FFAR4 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFFAR4
EVEXFFAR4
GoPubMedFFAR4
iHOPFFAR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:06:03 CET 2017

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