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FGB (fibrinogen beta chain)

Identity

Other names-
HGNC (Hugo) FGB
LocusID (NCBI) 2244
Location 4q31.3
Location_base_pair Starts at 155484132 and ends at 155493915 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FGB   3662
Cards
Entrez_Gene (NCBI)FGB  2244  fibrinogen beta chain
GeneCards (Weizmann)FGB
Ensembl (Hinxton) [Gene_View]  chr4:155484132-155493915 [Contig_View]  FGB [Vega]
AceView (NCBI)FGB
Genatlas (Paris)FGB
WikiGenes2244
SOURCE (Princeton)NM_001184741 NM_005141
Genomic and cartography
GoldenPath (UCSC)FGB  -  4q31.3   chr4:155484132-155493915 +  4q31.3   [Description]    (hg19-Feb_2009)
EnsemblFGB - 4q31.3 [CytoView]
Mapping of homologs : NCBIFGB [Mapview]
OMIM134830   202400   
Gene and transcription
Genbank (Entrez)AI174804 AK303788 AK309592 AK311683 AK312972
RefSeq transcript (Entrez)NM_001184741 NM_005141
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NG_008833 NT_016354 NW_001838921 NW_004929320
Consensus coding sequences : CCDS (NCBI)FGB
Cluster EST : UnigeneHs.300774 [ NCBI ]
CGAP (NCI)Hs.300774
Alternative Splicing : Fast-db (Paris)GSHG0022931
Gene ExpressionFGB [ NCBI-GEO ]     FGB [ SEEK ]   FGB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02675 (Uniprot)
NextProtP02675  [Medical]
With graphics : InterProP02675
Splice isoforms : SwissVarP02675 (Swissvar)
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)Fibrinogen_a/b/g_C_1    Fibrinogen_a/b/g_C_2    Fibrinogen_a/b/g_C_dom    Fibrinogen_a/b/g_coil_dom    Fibrinogen_CS   
Related proteins : CluSTrP02675
Domain families : Pfam (Sanger)Fib_alpha (PF08702)    Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam08702    pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
DMDM Disease mutations2244
Blocks (Seattle)P02675
PDB (SRS)1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2H43    2HLO    2HOD    2HPC    2OYH    2OYI    2Q9I    2XNX    2XNY    2Z4E    3BVH    3E1I    3GHG    3H32    3HUS   
PDB (PDBSum)1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2H43    2HLO    2HOD    2HPC    2OYH    2OYI    2Q9I    2XNX    2XNY    2Z4E    3BVH    3E1I    3GHG    3H32    3HUS   
PDB (IMB)1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2H43    2HLO    2HOD    2HPC    2OYH    2OYI    2Q9I    2XNX    2XNY    2Z4E    3BVH    3E1I    3GHG    3H32    3HUS   
PDB (RSDB)1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2H43    2HLO    2HOD    2HPC    2OYH    2OYI    2Q9I    2XNX    2XNY    2Z4E    3BVH    3E1I    3GHG    3H32    3HUS   
Peptide AtlasP02675
HPRD00620
IPIIPI00298497   IPI00816687   IPI00965713   IPI00878769   
Protein Interaction databases
DIP (DOE-UCLA)P02675
IntAct (EBI)P02675
BioGRIDFGB
InParanoidP02675
Interologous Interaction database P02675
IntegromeDBFGB
STRING (EMBL)FGB
Ontologies - Pathways
Ontology : AmiGOplatelet degranulation  receptor binding  protein binding  extracellular region  extracellular region  fibrinogen complex  extracellular space  plasma membrane  cell cortex  signal transduction  blood coagulation  external side of plasma membrane  cell surface  platelet activation  protein binding, bridging  platelet alpha granule  platelet alpha granule lumen  chaperone binding  protein polymerization  response to calcium ion  blood microparticle  
Ontology : EGO-EBIplatelet degranulation  receptor binding  protein binding  extracellular region  extracellular region  fibrinogen complex  extracellular space  plasma membrane  cell cortex  signal transduction  blood coagulation  external side of plasma membrane  cell surface  platelet activation  protein binding, bridging  platelet alpha granule  platelet alpha granule lumen  chaperone binding  protein polymerization  response to calcium ion  blood microparticle  
Pathways : BIOCARTAExtrinsic Prothrombin Activation Pathway [Genes]    Intrinsic Prothrombin Activation Pathway [Genes]    Acute Myocardial Infarction [Genes]    Fibrinolysis Pathway [Genes]   
Pathways : KEGGComplement and coagulation cascades   
REACTOMEFGB
Protein Interaction DatabaseFGB
Wikipedia pathwaysFGB
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FGB
SNP (GeneSNP Utah)FGB
SNP : HGBaseFGB
Genetic variants : HAPMAPFGB
1000_GenomesFGB 
Somatic Mutations in Cancer : COSMICFGB 
CONAN: Copy Number AnalysisFGB 
Mutations and Diseases : HGMDFGB
OMIM134830    202400   
GENETestsFGB
Disease Genetic AssociationFGB
Huge Navigator FGB [HugePedia]  FGB [HugeCancerGEM]
Genomic VariantsFGB  FGB [DGVbeta]
Exome VariantFGB
dbVarFGB
ClinVarFGB
snp3D : Map Gene to Disease2244
General knowledge
Homologs : HomoloGeneFGB
Homology/Alignments : Family Browser (UCSC)FGB
Phylogenetic Trees/Animal Genes : TreeFamFGB
Chemical/Protein Interactions : CTD2244
Chemical/Pharm GKB GenePA163
Clinical trialFGB
Other databases
Probes
Litterature
PubMed321 Pubmed reference(s) in Entrez
CoreMineFGB
iHOPFGB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:12:41 CEST 2014

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