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FGD1 (FYVE, RhoGEF and PH domain containing 1)

Identity

Other namesAAS
FGDY
MRXS16
ZFYVE3
HGNC (Hugo) FGD1
LocusID (NCBI) 2245
Atlas_Id 43259
Location Xp11.22
Location_base_pair Starts at 54471887 and ends at 54522599 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C6orf120 (6q27) / FGD1 (Xp11.22)FAM167A-AS1 (8p23.1) / FGD1 (Xp11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGD1   3663
Cards
Entrez_Gene (NCBI)FGD1  2245  FYVE, RhoGEF and PH domain containing 1
GeneCards (Weizmann)FGD1
Ensembl hg19 (Hinxton)ENSG00000102302 [Gene_View]  chrX:54471887-54522599 [Contig_View]  FGD1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000102302 [Gene_View]  chrX:54471887-54522599 [Contig_View]  FGD1 [Vega]
ICGC DataPortalENSG00000102302
TCGA cBioPortalFGD1
AceView (NCBI)FGD1
Genatlas (Paris)FGD1
WikiGenes2245
SOURCE (Princeton)FGD1
Genomic and cartography
GoldenPath hg19 (UCSC)FGD1  -     chrX:54471887-54522599 -  Xp11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FGD1  -     Xp11.22   [Description]    (hg38-Dec_2013)
EnsemblFGD1 - Xp11.22 [CytoView hg19]  FGD1 - Xp11.22 [CytoView hg38]
Mapping of homologs : NCBIFGD1 [Mapview hg19]  FGD1 [Mapview hg38]
OMIM300546   305400   
Gene and transcription
Genbank (Entrez)AK226117 AK299635 BC034530 U11690
RefSeq transcript (Entrez)NM_004463
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_008054 NT_011630 NW_004929442
Consensus coding sequences : CCDS (NCBI)FGD1
Cluster EST : UnigeneHs.709201 [ NCBI ]
CGAP (NCI)Hs.709201
Alternative Splicing : Fast-db (Paris)GSHG0032120
Alternative Splicing GalleryENSG00000102302
Gene ExpressionFGD1 [ NCBI-GEO ]   FGD1 [ EBI - ARRAY_EXPRESS ]   FGD1 [ SEEK ]   FGD1 [ MEM ]
Gene Expression Viewer (FireBrowse)FGD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)2245
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98174 (Uniprot)
NextProtP98174  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98174
Splice isoforms : SwissVarP98174 (Swissvar)
PhosPhoSitePlusP98174
Domaine pattern : Prosite (Expaxy)DH_2 (PS50010)    PH_DOMAIN (PS50003)    ZF_FYVE (PS50178)   
Domains : Interpro (EBI)DH-domain    PH_dom-like    PH_domain    Znf_FYVE    Znf_FYVE-rel    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)    PH (PF00169)    RhoGEF (PF00621)   
Domain families : Pfam (NCBI)pfam01363    pfam00169    pfam00621   
Domain families : Smart (EMBL)FYVE (SM00064)  PH (SM00233)  RhoGEF (SM00325)  
DMDM Disease mutations2245
Blocks (Seattle)FGD1
SuperfamilyP98174
Human Protein AtlasENSG00000102302
Peptide AtlasP98174
HPRD02373
IPIIPI00024312   
Protein Interaction databases
DIP (DOE-UCLA)P98174
IntAct (EBI)P98174
FunCoupENSG00000102302
BioGRIDFGD1
STRING (EMBL)FGD1
ZODIACFGD1
Ontologies - Pathways
QuickGOP98174
Ontology : AmiGOruffle  guanyl-nucleotide exchange factor activity  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  cytoplasm  Golgi apparatus  cytosol  cytoskeleton  cytoskeleton organization  signal transduction  multicellular organism development  regulation of cell shape  organ morphogenesis  lamellipodium  actin cytoskeleton organization  small GTPase binding  regulation of Rho protein signal transduction  positive regulation of apoptotic process  regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  filopodium assembly  metal ion binding  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBIruffle  guanyl-nucleotide exchange factor activity  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  cytoplasm  Golgi apparatus  cytosol  cytoskeleton  cytoskeleton organization  signal transduction  multicellular organism development  regulation of cell shape  organ morphogenesis  lamellipodium  actin cytoskeleton organization  small GTPase binding  regulation of Rho protein signal transduction  positive regulation of apoptotic process  regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  positive regulation of GTPase activity  filopodium assembly  metal ion binding  regulation of small GTPase mediated signal transduction  
Pathways : KEGGRegulation of actin cytoskeleton   
NDEx Network
Atlas of Cancer Signalling NetworkFGD1
Wikipedia pathwaysFGD1
Orthology - Evolution
OrthoDB2245
GeneTree (enSembl)ENSG00000102302
Phylogenetic Trees/Animal Genes : TreeFamFGD1
Homologs : HomoloGeneFGD1
Homology/Alignments : Family Browser (UCSC)FGD1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerFGD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGD1
dbVarFGD1
ClinVarFGD1
1000_GenomesFGD1 
Exome Variant ServerFGD1
ExAC (Exome Aggregation Consortium)FGD1 (select the gene name)
SNP (GeneSNP Utah)FGD1
SNP : HGBaseFGD1
Genetic variants : HAPMAPFGD1
Genomic Variants (DGV)FGD1 [DGVbeta]
Mutations
ICGC Data PortalFGD1 
TCGA Data PortalFGD1 
Broad Tumor PortalFGD1
OASIS PortalFGD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGD1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch FGD1
DgiDB (Drug Gene Interaction Database)FGD1
DoCM (Curated mutations)FGD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGD1 (select a term)
intoGenFGD1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:54471887-54522599
CONAN: Copy Number AnalysisFGD1 
Mutations and Diseases : HGMDFGD1
OMIM300546    305400   
MedgenFGD1
Genetic Testing Registry FGD1
NextProtP98174 [Medical]
TSGene2245
GENETestsFGD1
Huge Navigator FGD1 [HugePedia]  FGD1 [HugeCancerGEM]
snp3D : Map Gene to Disease2245
BioCentury BCIQFGD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2245
Chemical/Pharm GKB GenePA28102
Clinical trialFGD1
Miscellaneous
canSAR (ICR)FGD1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGD1
GoPubMedFGD1
iHOPFGD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Apr 16 17:44:53 CEST 2016

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