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FGD1 (FYVE, RhoGEF and PH domain containing 1)

Identity

Other namesAAS
FGDY
MRXS16
ZFYVE3
HGNC (Hugo) FGD1
LocusID (NCBI) 2245
Location Xp11.22
Location_base_pair Starts at 54471887 and ends at 54522599 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FGD1   3663
Entrez_Gene (NCBI)FGD1  2245  FYVE, RhoGEF and PH domain containing 1
Cards
GeneCards (Weizmann)FGD1
Ensembl (Hinxton)ENSG00000102302 [Gene_View]  chrX:54471887-54522599 [Contig_View]  FGD1 [Vega]
AceView (NCBI)FGD1
Genatlas (Paris)FGD1
SOURCE (Stanford)NM_004463
Genomic and cartography
GoldenPath (UCSC)FGD1  -  Xp11.22   chrX:54471887-54522599 -  Xp11.22   [Description]    (hg19-Feb_2009)
EnsemblFGD1 - Xp11.22 [CytoView]
Mapping of homologs : NCBIFGD1 [Mapview]
OMIM300546   305400   
Gene and transcription
Genbank (Entrez)AK226117 AK299635 BC034530 U11690
RefSeq transcript (SRS)NM_004463
RefSeq transcript (Entrez)NM_004463
RefSeq genomic (SRS)AC_000155 NC_000023 NC_018934 NG_008054 NT_011630 NW_001842370 NW_004078122
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_008054 NT_011630 NW_001842370 NW_004078122
Consensus coding sequences : CCDS (NCBI)FGD1
Cluster EST : UnigeneHs.709201 [ SRS ] Hs.709201 [ NCBI ]
CGAP (NCI)Hs.709201
Alternative Splicing : Fast-db (Paris)GSHG0032120
Alternative Splicing GalleryENSG00000102302
Gene ExpressionFGD1 [ NCBI-GEO ]   FGD1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98174 (SRS) P98174 (Uniprot)
NextProtP98174
With graphics : InterProP98174
Splice isoforms : SwissVarP98174(Swissvar)
Domaine pattern : Prosite (SRS)DH_1 (PS00741)    DH_2 (PS50010)    PH_DOMAIN (PS50003)    ZF_FYVE (PS50178)   
Domaine pattern : Prosite (Expaxy)DH_1 (PS00741)    DH_2 (PS50010)    PH_DOMAIN (PS50003)    ZF_FYVE (PS50178)   
Domains : Interpro (SRS)DH-domain    PH_like_dom    Pleckstrin_homology    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domains : Interpro (EBI)DH-domain    PH_like_dom    Pleckstrin_homology    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Related proteins : CluSTrP98174
Domain families : Pfam (SRS)FYVE (PF01363)    PH (PF00169)    RhoGEF (PF00621)   
Domain families : Pfam (Sanger)FYVE (PF01363)    PH (PF00169)    RhoGEF (PF00621)   
Domain families : Pfam (NCBI)pfam01363    pfam00169    pfam00621   
Domain families : Smart (EMBL)FYVE (SM00064)  PH (SM00233)  RhoGEF (SM00325)  
DMDM2245
Blocks (Seattle)P98174
Human Protein AtlasENSG00000102302
HPRD02373
IPIIPI00024312   
Protein Interaction databases
DIP (DOE-UCLA)P98174
IntAct (EBI)P98174
FunCoupENSG00000102302
REACTOMEFGD1
Protein Interaction Database2245
BioGRIDFGD1
InParanoidP98174
Interologous Interaction database P98174
IntegromeDBFGD1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FGD1
SNP (GeneSNP Utah)FGD1
SNP : HGBaseFGD1
Genetic variants : HAPMAPFGD1
Somatic Mutations in Cancer : COSMICFGD1 
CONAN: Copy Number AnalysisFGD1 
Mutations and Diseases : HGMDFGD1
OMIM300546    305400   
GENETests300546    305400   
Disease Genetic AssociationFGD1
Huge Navigator FGD1 [HugePedia]  FGD1 [HugeCancerGEM]
Genomic VariantsFGD1  FGD1 [DGVbeta]
snp3D : Map Gene to Disease2245
General knowledge
Homologs : HomoloGeneFGD1
Homology/Alignments : Family Browser (UCSC)FGD1
Phylogenetic Trees/Animal Genes : TreeFamFGD1
Chemical/Protein Interactions : CTD2245
Chemical/Pharm GKB GenePA28102
Clinical trialFGD1
Cancer Resource (Charite)ENSG00000102302
Ontology : AmiGOruffle  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  phospholipid binding  nucleus  cytoplasm  cytoplasm  Golgi apparatus  cytosol  cytoskeleton  plasma membrane  apoptotic process  cytoskeleton organization  signal transduction  small GTPase mediated signal transduction  multicellular organismal development  regulation of cell shape  organ morphogenesis  lamellipodium  actin cytoskeleton organization  small GTPase binding  regulation of Cdc42 GTPase activity  filopodium assembly  metal ion binding  nerve growth factor receptor signaling pathway  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBIruffle  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  phospholipid binding  nucleus  cytoplasm  cytoplasm  Golgi apparatus  cytosol  cytoskeleton  plasma membrane  apoptotic process  cytoskeleton organization  signal transduction  small GTPase mediated signal transduction  multicellular organismal development  regulation of cell shape  organ morphogenesis  lamellipodium  actin cytoskeleton organization  small GTPase binding  regulation of Cdc42 GTPase activity  filopodium assembly  metal ion binding  nerve growth factor receptor signaling pathway  regulation of small GTPase mediated signal transduction  
Pathways : KEGGRegulation of actin cytoskeleton
Other databases
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
PubGeneFGD1
iHOPFGD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:43:33 CEST 2013
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