FGD5 (FYVE, RhoGEF and PH domain containing 5)

Identity

Other names	ZFYVE23
HGNC	FGD5
Location	3p25.1
Location_base_pair	Starts at 14835473 and ends at 14951076 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	FGD5   19117
Entrez_Gene	FGD5  152273  FYVE, RhoGEF and PH domain containing 5
	Cards
GeneCards	FGD5
Ensembl	FGD5 [Search_View]   ENSG00000154783 [Gene_View]
Genatlas	FGD5
GeneLynx	FGD5
eGenome	FGD5
euGene	152273
	Genomic and cartography
GoldenPath	FGD5  -  3p25.1   chr3:14835473-14951076 +  3p24.3   [Description]    (hg18-March_2006)
Ensembl	FGD5 - 3p24.3 [CytoView]
NCBI	Mapview
HomoloGene	FGD5
	Gene and transcription
Genbank	AK096856 [ ENTREZ ]
Genbank	AK097276 [ ENTREZ ]
Genbank	AK123054 [ ENTREZ ]
Genbank	AK131078 [ ENTREZ ]
Genbank	BC035364 [ ENTREZ ]
RefSeq	NM_152536 [ SRS ]    NM_152536 [ ENTREZ ]
RefSeq	AC_000046 [ SRS ]    AC_000046 [ ENTREZ ]
RefSeq	AC_000135 [ SRS ]    AC_000135 [ ENTREZ ]
RefSeq	NC_000003 [ SRS ]    NC_000003 [ ENTREZ ]
RefSeq	NT_022517 [ SRS ]    NT_022517 [ ENTREZ ]
RefSeq	NW_001838877 [ SRS ]    NW_001838877 [ ENTREZ ]
RefSeq	NW_921651 [ SRS ]    NW_921651 [ ENTREZ ]
AceView	FGD5 AceView - NCBI
Unigene	Hs.412406 [ SRS ]    Hs.412406 [ NCBI ]     HS412406 [ spliceNest ]
Fast-db	2633 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q6ZNL6 [ SRS]    Q6ZNL6 [ EXPASY ]     Q6ZNL6 [ INTERPRO ]     Q6ZNL6 [ UNIPROT ]
Prosite	PS50010 DH_2 [ SRS ]    PS50010 DH_2 [ Expasy ]
Prosite	PS50003 PH_DOMAIN [ SRS ]    PS50003 PH_DOMAIN [ Expasy ]
Prosite	PS50178 ZF_FYVE [ SRS ]    PS50178 ZF_FYVE [ Expasy ]
Interpro	IPR000219 DH-domain [ SRS ]    IPR000219 DH-domain [ EBI ]
Interpro	IPR001849 PH [ SRS ]    IPR001849 PH [ EBI ]
Interpro	IPR011993 PH_type [ SRS ]    IPR011993 PH_type [ EBI ]
Interpro	IPR000306 Znf_FYVE [ SRS ]    IPR000306 Znf_FYVE [ EBI ]
Interpro	IPR017455 Znf_FYVE-rel [ SRS ]    IPR017455 Znf_FYVE-rel [ EBI ]
Interpro	IPR013083 Znf_RING/FYVE/PHD [ SRS ]    IPR013083 Znf_RING/FYVE/PHD [ EBI ]
CluSTr	Q6ZNL6
Pfam	PF01363 FYVE [ SRS ]    PF01363 FYVE [ Sanger ]    pfam01363 [ NCBI-CDD ]
Pfam	PF00169 PH [ SRS ]    PF00169 PH [ Sanger ]    pfam00169 [ NCBI-CDD ]
Pfam	PF00621 RhoGEF [ SRS ]    PF00621 RhoGEF [ Sanger ]    pfam00621 [ NCBI-CDD ]
Smart	SM00064 FYVE [EMBL]
Smart	SM00233 PH [EMBL]
Smart	SM00325 RhoGEF [EMBL]
Prodom	PD040407 Peptidase_S48[INRA-Toulouse]
Prodom	Q6ZNL6 FGD5_HUMAN [ Domain structure ]   Q6ZNL6 FGD5_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q6ZNL6
HPRD	13322
	Protein Interaction databases
DIP	Q6ZNL6
IntAct	Q6ZNL6
	Polymorphism : SNP, mutations, diseases
SNP	FGD5 [dbSNP-NCBI]
SNP	NM_152536 [SNP-NCI]
SNP	FGD5 [GeneSNPs - Utah]  FGD5] [HGBASE - SRS]
HAPMAP	FGD5 [HAPMAP]
COSMIC	FGD5 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	FGD5
	General knowledge
Family Browser	FGD5 [UCSC Family Browser]
SOURCE	NM_152536
SMD	Hs.412406
SAGE	Hs.412406
GO	ruffle [Amigo]  ruffle
GO	guanyl-nucleotide exchange factor activity [Amigo]  guanyl-nucleotide exchange factor activity
GO	Rho guanyl-nucleotide exchange factor activity [Amigo]  Rho guanyl-nucleotide exchange factor activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	cytoplasm [Amigo]  cytoplasm
GO	Golgi apparatus [Amigo]  Golgi apparatus
GO	cytoskeleton [Amigo]  cytoskeleton
GO	cytoskeleton organization and biogenesis [Amigo]  cytoskeleton organization and biogenesis
GO	zinc ion binding [Amigo]  zinc ion binding
GO	regulation of cell shape [Amigo]  regulation of cell shape
GO	lamellipodium [Amigo]  lamellipodium
GO	actin cytoskeleton organization and biogenesis [Amigo]  actin cytoskeleton organization and biogenesis
GO	small GTPase binding [Amigo]  small GTPase binding
GO	regulation of Rho protein signal transduction [Amigo]  regulation of Rho protein signal transduction
GO	regulation of Cdc42 GTPase activity [Amigo]  regulation of Cdc42 GTPase activity
GO	filopodium formation [Amigo]  filopodium formation
GO	metal ion binding [Amigo]  metal ion binding
PubGene	FGD5
TreeFam	FGD5
CTD	152273 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FGD5 Related clones (RZPD - Berlin)
	PubMed
PubMed	4 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:41:26 2008