Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FGF1 (fibroblast growth factor 1 (acidic))

Identity

Other namesAFGF
ECGF
ECGF-beta
ECGFA
ECGFB
FGF-alpha
FGFA
GLIO703
HBGF1
HGNC (Hugo) FGF1
Location 5q31.3
Location_base_pair Starts at 141973782 and ends at 141974601 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FGF1   3665
Entrez_Gene (NCBI)FGF1  2246  fibroblast growth factor 1 (acidic)
Cards
GeneCards (Weizmann)FGF1
Ensembl (Hinxton)ENSG00000113578 [Gene_View]  FGF1 [Vega]
AceView (NCBI)FGF1
Genatlas (Paris)FGF1
euGene (Indiana)2246
SOURCE (Stanford)NM_000800 NM_001144892 NM_001144934 NM_001144935 NM_033136 NM_033137
Gene Expression (Array Express) ENSG00000113578
Genomic and cartography
GoldenPath (UCSC)FGF1  -  5q31.3   chr5:141973782-141974601 -  5q31.3   [Description]    (hg19-Feb_2009)
EnsemblFGF1 - 5q31.3 [CytoView]
Mapping of homologs : NCBIFGF1 [Mapview]
OMIM131220   
Gene and transcription
Gene : Genbank (Entrez)AF211169 AI283639 AK289762 AK312301 BC032697
Reference sequence (RefSeq transcript) :SRSNM_000800 NM_001144892 NM_001144934 NM_001144935 NM_033136 NM_033137
Reference transcript : EntrezNM_000800 NM_001144892 NM_001144934 NM_001144935 NM_033136 NM_033137
RefSeq genomic : SRSAC_000048 AC_000137 NC_000005 NT_029289 NW_001838953 NW_922784
RefSeq genomic : EntrezAC_000048 AC_000137 NC_000005 NT_029289 NW_001838953 NW_922784
Consensus coding sequences : CCDS NCBIFGF1
Cluster EST : UnigeneHs.483635 [ SRS ] Hs.483635 [ NCBI ]
Alternative Splicing : Fast-db (Paris)11481
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtP05230 (SRS) P05230 (Expasy) P05230 (Uniprot)
With graphics : InterProP05230
Splice isoforms : VarSplice FASTAP05230(VarSplice FASTA)
Domaine pattern : Prosite (SRS)HBGF_FGF (PS00247)   
Domain pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (SRS)Cytokine_IL1-like    GF_heparin-bd    IL1_HBGF   
Domains : Interpro (EBI)Cytokine_IL1-like    GF_heparin-bd    IL1_HBGF   
Related proteins : CluSTrP05230
Domain families : Pfam SRSFGF (PF00167)   
Domain families : Pfam SangerFGF (PF00167)   
Domain families : Pfam NCBIpfam00167   
Domain families : Smart EMBLFGF (SM00442)  
Blocks (Seattle)P05230
Crystal structure of protein : PDB SRS1AXM    1DJS    1DZC    1DZD    1E0O    1EVT    1HKN    1JQZ    1JT3    1JT4    1JT5    1JT7    1JTC    1JY0    1K5U    1K5V    1M16    1NZK    1P63    1PZZ    1Q03    1Q04    1QCT    1RG8    1RML    1RY7    1YTO    1Z2V    1Z4S    2AFG    2AQZ    2AXM    2ERM    2HW9    2HWA    2HWM    2HZ9    2K43    2K4A    2K8R    2KI4    2KI6    2NTD    2Q9X    2RQ9    3B9U    3BA4    3BA5    3BA7    3BAD    3BAG    3BAH    3BAO    3BAQ    3BAU    3BAV    3BB2    3CQA    3CRG    3CRH    3CRI    3CU1    3FGM    3FJ8    3FJ9    3FJA    3FJB    3FJC    3FJD    3FJE    3FJF    3FJH    3FJI    3FJJ    3FJK    3HOM    3JUT    3K1X   
Crystal structure of protein : PDBSum1AXM    1DJS    1DZC    1DZD    1E0O    1EVT    1HKN    1JQZ    1JT3    1JT4    1JT5    1JT7    1JTC    1JY0    1K5U    1K5V    1M16    1NZK    1P63    1PZZ    1Q03    1Q04    1QCT    1RG8    1RML    1RY7    1YTO    1Z2V    1Z4S    2AFG    2AQZ    2AXM    2ERM    2HW9    2HWA    2HWM    2HZ9    2K43    2K4A    2K8R    2KI4    2KI6    2NTD    2Q9X    2RQ9    3B9U    3BA4    3BA5    3BA7    3BAD    3BAG    3BAH    3BAO    3BAQ    3BAU    3BAV    3BB2    3CQA    3CRG    3CRH    3CRI    3CU1    3FGM    3FJ8    3FJ9    3FJA    3FJB    3FJC    3FJD    3FJE    3FJF    3FJH    3FJI    3FJJ    3FJK    3HOM    3JUT    3K1X   
Crystal structure of protein : IMB1AXM    1DJS    1DZC    1DZD    1E0O    1EVT    1HKN    1JQZ    1JT3    1JT4    1JT5    1JT7    1JTC    1JY0    1K5U    1K5V    1M16    1NZK    1P63    1PZZ    1Q03    1Q04    1QCT    1RG8    1RML    1RY7    1YTO    1Z2V    1Z4S    2AFG    2AQZ    2AXM    2ERM    2HW9    2HWA    2HWM    2HZ9    2K43    2K4A    2K8R    2KI4    2KI6    2NTD    2Q9X    2RQ9    3B9U    3BA4    3BA5    3BA7    3BAD    3BAG    3BAH    3BAO    3BAQ    3BAU    3BAV    3BB2    3CQA    3CRG    3CRH    3CRI    3CU1    3FGM    3FJ8    3FJ9    3FJA    3FJB    3FJC    3FJD    3FJE    3FJF    3FJH    3FJI    3FJJ    3FJK    3HOM    3JUT    3K1X   
Crystal structure of protein : PDB RSDB1AXM    1DJS    1DZC    1DZD    1E0O    1EVT    1HKN    1JQZ    1JT3    1JT4    1JT5    1JT7    1JTC    1JY0    1K5U    1K5V    1M16    1NZK    1P63    1PZZ    1Q03    1Q04    1QCT    1RG8    1RML    1RY7    1YTO    1Z2V    1Z4S    2AFG    2AQZ    2AXM    2ERM    2HW9    2HWA    2HWM    2HZ9    2K43    2K4A    2K8R    2KI4    2KI6    2NTD    2Q9X    2RQ9    3B9U    3BA4    3BA5    3BA7    3BAD    3BAG    3BAH    3BAO    3BAQ    3BAU    3BAV    3BB2    3CQA    3CRG    3CRH    3CRI    3CU1    3FGM    3FJ8    3FJ9    3FJA    3FJB    3FJC    3FJD    3FJE    3FJF    3FJH    3FJI    3FJJ    3FJK    3HOM    3JUT    3K1X   
Human Protein AtlasENSG00000113578
HPRD00567
Protein Interaction databases
DIP (DOE-UCLA)P05230
IntAct (EBI)P05230
FunCoupENSG00000113578
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIFGF1
SNP : GeneSNP UtahFGF1
SNP : HGBaseFGF1
Genetic variants : HAPMAPFGF1
Somatic Mutations in Cancer : COSMICFGF1 
Mutations and Diseases : HGMDFGF1
Hereditary diseases : OMIM131220   
Hereditary diseases : GENETests131220   
Diseases : Genetic AssociationFGF1
General knowledge
Homologs : HomoloGeneFGF1
Homology/Alignments : Family Browser UCSCFGF1
Phylogenetic Trees/Animal Genes : TreeFamFGF1
Chemical/Protein Interactions : CTD2246
Keywords Ontology : AmiGOangiogenesis  induction of an organ  positive regulation of protein amino acid phosphorylation  fibroblast growth factor receptor binding  protein binding  extracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  nucleus  nucleolus  cytoplasm  cytosol  signal transduction  intracellular protein kinase cascade  multicellular organismal development  nervous system development  growth factor activity  heparin binding  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  anatomical structure morphogenesis  positive regulation of gene-specific transcription from RNA polymerase II promoter  cell differentiation  lung development  cellular response to heat  positive regulation of cell adhesion  S100 alpha binding  positive regulation of epithelial cell proliferation  positive regulation of cell division  
Keywords Ontology : EGO-EBIangiogenesis  induction of an organ  positive regulation of protein amino acid phosphorylation  fibroblast growth factor receptor binding  protein binding  extracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  nucleus  nucleolus  cytoplasm  cytosol  signal transduction  intracellular protein kinase cascade  multicellular organismal development  nervous system development  growth factor activity  heparin binding  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  anatomical structure morphogenesis  positive regulation of gene-specific transcription from RNA polymerase II promoter  cell differentiation  lung development  cellular response to heat  positive regulation of cell adhesion  S100 alpha binding  positive regulation of epithelial cell proliferation  positive regulation of cell division  
Pathways : BIOCARTABTG family proteins and cell cycle regulation [Genes]   
Pathways : KEGGRegulation of actin cytoskeletonMAPK signaling pathway
Other databases
Probes
Probes : ImagenesFGF1 Related clones (RZPD - Berlin)
Literature
PubMed134 Pubmed reference(s) in Entrez
PubGeneFGF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated07-2010Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 31 19:59:01 CEST 2010
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