Atlas of Genetics and Cytogenetics in Oncology and Haematology

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FGF10 (fibroblast growth factor 10)

Identity

Other names-
HGNC (Hugo) FGF10
LocusID (NCBI) 2255
Location 5p12
Location_base_pair Starts at 44305097 and ends at 44388784 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FGF10   3666
Entrez_Gene (NCBI)FGF10  2255  fibroblast growth factor 10
Cards
GeneCards (Weizmann)FGF10
Ensembl (Hinxton) [Gene_View]  chr5:44305097-44388784 [Contig_View]  FGF10 [Vega]
AceView (NCBI)FGF10
Genatlas (Paris)FGF10
SOURCE (Stanford)NM_004465
Genomic and cartography
GoldenPath (UCSC)FGF10  -  5p12   chr5:44305097-44388784 -  5p12   [Description]    (hg19-Feb_2009)
EnsemblFGF10 - 5p12 [CytoView]
Mapping of homologs : NCBIFGF10 [Mapview]
OMIM149730   180920   602115   
Gene and transcription
Genbank (Entrez)AB002097 AF411527 AF508782 AK315314 BC069561
RefSeq transcript (SRS)NM_004465
RefSeq transcript (Entrez)NM_004465
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NG_011446 NT_006576 NW_001838933 NW_004929321
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NG_011446 NT_006576 NW_001838933 NW_004929321
Consensus coding sequences : CCDS (NCBI)FGF10
Cluster EST : UnigeneHs.664499 [ SRS ] Hs.664499 [ NCBI ]
CGAP (NCI)Hs.664499
Alternative Splicing : Fast-db (Paris)GSHG0024774
Gene ExpressionFGF10 [ NCBI-GEO ]   FGF10 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15520 (SRS) O15520 (Uniprot)
NextProtO15520  [Medical]
With graphics : InterProO15520
Splice isoforms : SwissVarO15520(Swissvar)
Domaine pattern : Prosite (SRS)HBGF_FGF (PS00247)   
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (SRS)Cytokine_IL1-like    FGF10    Fibroblast_GF_fam    IL-1_fam/FGF_fam   
Domains : Interpro (EBI)Cytokine_IL1-like    FGF10    Fibroblast_GF_fam    IL-1_fam/FGF_fam   
Related proteins : CluSTrO15520
Domain families : Pfam (SRS)FGF (PF00167)   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
DMDM2255
Blocks (Seattle)O15520
PDB (SRS)1NUN   
PDB (PDBSum)1NUN   
PDB (IMB)1NUN   
PDB (RSDB)1NUN   
HPRD03665
IPIIPI00007307   IPI00964243   
Protein Interaction databases
DIP (DOE-UCLA)O15520
IntAct (EBI)O15520
REACTOMEFGF10
Protein Interaction Database2255
BioGRIDFGF10
InParanoidO15520
Interologous Interaction database O15520
IntegromeDBFGF10
Gene fusion - rearrangments
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FGF10
SNP (GeneSNP Utah)FGF10
SNP : HGBaseFGF10
Genetic variants : HAPMAPFGF10
Somatic Mutations in Cancer : COSMICFGF10 
CONAN: Copy Number AnalysisFGF10 
Mutations and Diseases : HGMDFGF10
OMIM149730    180920    602115   
GENETests149730    180920    602115   
Disease Genetic AssociationFGF10
Huge Navigator FGF10 [HugePedia]  FGF10 [HugeCancerGEM]
Genomic VariantsFGF10  FGF10 [DGVbeta]
ClinVarFGF10
snp3D : Map Gene to Disease2255
General knowledge
Homologs : HomoloGeneFGF10
Homology/Alignments : Family Browser (UCSC)FGF10
Phylogenetic Trees/Animal Genes : TreeFamFGF10
Chemical/Protein Interactions : CTD2255
Chemical/Pharm GKB GenePA28106
Clinical trialFGF10
Ontology : AmiGOactivation of MAPK activity  angiogenesis  metanephros development  organ induction  mesonephros development  blood vessel remodeling  metanephros morphogenesis  fibroblast growth factor receptor binding  type 2 fibroblast growth factor receptor binding  extracellular region  extracellular space  nucleus  plasma membrane  epidermal growth factor receptor signaling pathway  determination of left/right symmetry  salivary gland development  growth factor activity  heparin binding  negative regulation of cell proliferation  insulin receptor signaling pathway  fibroblast growth factor receptor signaling pathway  regulation of smoothened signaling pathway  embryonic pattern specification  cell surface  cell surface  epithelial cell migration  positive regulation of epithelial cell migration  positive regulation of keratinocyte proliferation  pituitary gland development  embryonic genitalia morphogenesis  thyroid gland development  otic vesicle formation  positive regulation of vascular endothelial growth factor receptor signaling pathway  extracellular matrix  pancreas development  hair follicle morphogenesis  embryonic camera-type eye development  actin cytoskeleton reorganization  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle  response to estradiol  response to lipopolysaccharide  positive regulation of ATPase activity  lacrimal gland development  regulation of activin receptor signaling pathway  protein localization to cell surface  somatic stem cell maintenance  Fc-epsilon receptor signaling pathway  chemoattractant activity  wound healing  tissue regeneration  odontogenesis of dentin-containing tooth  muscle cell fate commitment  negative regulation of apoptotic process  positive regulation of MAPK cascade  keratinocyte proliferation  innate immune response  positive regulation of DNA repair  positive regulation of DNA replication  positive regulation of Notch signaling pathway  positive regulation of transcription, DNA-dependent  positive regulation of mitotic cell cycle  positive regulation of transcription from RNA polymerase II promoter  positive regulation of Ras protein signal transduction  regulation of saliva secretion  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of fibroblast proliferation  spleen development  thymus development  embryonic digestive tract morphogenesis  branching morphogenesis of an epithelial tube  female genitalia morphogenesis  male genitalia morphogenesis  positive regulation of lymphocyte proliferation  epithelial cell proliferation  urothelial cell proliferation  positive regulation of urothelial cell proliferation  positive regulation of epithelial cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  white fat cell differentiation  positive chemotaxis  induction of positive chemotaxis  smooth muscle cell differentiation  positive regulation of keratinocyte migration  radial glial cell differentiation  positive regulation of epithelial cell proliferation involved in wound healing  limb bud formation  lung epithelium development  lung saccule development  bronchiole morphogenesis  bud outgrowth involved in lung branching  mesenchymal-epithelial cell signaling involved in lung development  Type II pneumocyte differentiation  fibroblast growth factor receptor signaling pathway involved in mammary gland specification  mammary gland bud formation  submandibular salivary gland formation  epithelial cell proliferation involved in salivary gland morphogenesis  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  branch elongation involved in salivary gland morphogenesis  regulation of prostatic bud formation  semicircular canal fusion  mesenchymal cell differentiation involved in lung development  secretion by lung epithelial cell involved in lung growth  lung proximal/distal axis specification  tear secretion  positive regulation of white fat cell proliferation  ERK1 and ERK2 cascade  positive regulation of ERK1 and ERK2 cascade  Harderian gland development  negative regulation of cell cycle arrest  positive regulation of hair follicle cell proliferation  positive regulation of canonical Wnt receptor signaling pathway  
Ontology : EGO-EBIactivation of MAPK activity  angiogenesis  metanephros development  organ induction  mesonephros development  blood vessel remodeling  metanephros morphogenesis  fibroblast growth factor receptor binding  type 2 fibroblast growth factor receptor binding  extracellular region  extracellular space  nucleus  plasma membrane  epidermal growth factor receptor signaling pathway  determination of left/right symmetry  salivary gland development  growth factor activity  heparin binding  negative regulation of cell proliferation  insulin receptor signaling pathway  fibroblast growth factor receptor signaling pathway  regulation of smoothened signaling pathway  embryonic pattern specification  cell surface  cell surface  epithelial cell migration  positive regulation of epithelial cell migration  positive regulation of keratinocyte proliferation  pituitary gland development  embryonic genitalia morphogenesis  thyroid gland development  otic vesicle formation  positive regulation of vascular endothelial growth factor receptor signaling pathway  extracellular matrix  pancreas development  hair follicle morphogenesis  embryonic camera-type eye development  actin cytoskeleton reorganization  positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle  response to estradiol  response to lipopolysaccharide  positive regulation of ATPase activity  lacrimal gland development  regulation of activin receptor signaling pathway  protein localization to cell surface  somatic stem cell maintenance  Fc-epsilon receptor signaling pathway  chemoattractant activity  wound healing  tissue regeneration  odontogenesis of dentin-containing tooth  muscle cell fate commitment  negative regulation of apoptotic process  positive regulation of MAPK cascade  keratinocyte proliferation  innate immune response  positive regulation of DNA repair  positive regulation of DNA replication  positive regulation of Notch signaling pathway  positive regulation of transcription, DNA-dependent  positive regulation of mitotic cell cycle  positive regulation of transcription from RNA polymerase II promoter  positive regulation of Ras protein signal transduction  regulation of saliva secretion  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of fibroblast proliferation  spleen development  thymus development  embryonic digestive tract morphogenesis  branching morphogenesis of an epithelial tube  female genitalia morphogenesis  male genitalia morphogenesis  positive regulation of lymphocyte proliferation  epithelial cell proliferation  urothelial cell proliferation  positive regulation of urothelial cell proliferation  positive regulation of epithelial cell proliferation  positive regulation of peptidyl-tyrosine phosphorylation  white fat cell differentiation  positive chemotaxis  induction of positive chemotaxis  smooth muscle cell differentiation  positive regulation of keratinocyte migration  radial glial cell differentiation  positive regulation of epithelial cell proliferation involved in wound healing  limb bud formation  lung epithelium development  lung saccule development  bronchiole morphogenesis  bud outgrowth involved in lung branching  mesenchymal-epithelial cell signaling involved in lung development  Type II pneumocyte differentiation  fibroblast growth factor receptor signaling pathway involved in mammary gland specification  mammary gland bud formation  submandibular salivary gland formation  epithelial cell proliferation involved in salivary gland morphogenesis  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  branch elongation involved in salivary gland morphogenesis  regulation of prostatic bud formation  semicircular canal fusion  mesenchymal cell differentiation involved in lung development  secretion by lung epithelial cell involved in lung growth  lung proximal/distal axis specification  tear secretion  positive regulation of white fat cell proliferation  ERK1 and ERK2 cascade  positive regulation of ERK1 and ERK2 cascade  Harderian gland development  negative regulation of cell cycle arrest  positive regulation of hair follicle cell proliferation  positive regulation of canonical Wnt receptor signaling pathway  
Pathways : KEGGRegulation of actin cytoskeletonMAPK signaling pathway
Other databases
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
PubGeneFGF10
iHOPFGF10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Dec 3 19:52:50 CET 2013
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