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FGF13 (fibroblast growth factor 13)

Identity

Alias_symbol (synonym)FHF2
FGF2
Other aliasFGF-13
FHF-2
HGNC (Hugo) FGF13
LocusID (NCBI) 2258
Atlas_Id 40553
Location Xq26.3  [Link to chromosome band Xq26]
Location_base_pair Starts at 138631573 and ends at 139205023 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FGF13 (Xq26.3) / AL109749.1 ()FGF13 (Xq26.3) / CDK14 (7q21.13)FGF13 (Xq26.3) / DACH2 (Xq21.2)
FGF13 (Xq26.3) / NLRP3 (1q44)FGF13 (Xq26.3) / SGK1 (6q23.2)PLPPR5 (1p21.3) / FGF13 (Xq26.3)
FGF13 Xq26.3 AL109749.1FGF13 Xq26.3 / DACH2 Xq21.2FGF13 Xq26.3 / NLRP3 1q44

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGF13   3670
Cards
Entrez_Gene (NCBI)FGF13  2258  fibroblast growth factor 13
AliasesFGF-13; FGF2; FHF-2; FHF2
GeneCards (Weizmann)FGF13
Ensembl hg19 (Hinxton)ENSG00000129682 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129682 [Gene_View]  chrX:138631573-139205023 [Contig_View]  FGF13 [Vega]
ICGC DataPortalENSG00000129682
TCGA cBioPortalFGF13
AceView (NCBI)FGF13
Genatlas (Paris)FGF13
WikiGenes2258
SOURCE (Princeton)FGF13
Genetics Home Reference (NIH)FGF13
Genomic and cartography
GoldenPath hg38 (UCSC)FGF13  -     chrX:138631573-139205023 -  Xq26.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FGF13  -     Xq26.3   [Description]    (hg19-Feb_2009)
EnsemblFGF13 - Xq26.3 [CytoView hg19]  FGF13 - Xq26.3 [CytoView hg38]
Mapping of homologs : NCBIFGF13 [Mapview hg19]  FGF13 [Mapview hg38]
OMIM300070   
Gene and transcription
Genbank (Entrez)AF100143 AF100144 AF108756 AF199612 AF199613
RefSeq transcript (Entrez)NM_001139498 NM_001139500 NM_001139501 NM_001139502 NM_004114 NM_033642
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FGF13
Cluster EST : UnigeneHs.6540 [ NCBI ]
CGAP (NCI)Hs.6540
Alternative Splicing GalleryENSG00000129682
Gene ExpressionFGF13 [ NCBI-GEO ]   FGF13 [ EBI - ARRAY_EXPRESS ]   FGF13 [ SEEK ]   FGF13 [ MEM ]
Gene Expression Viewer (FireBrowse)FGF13 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2258
GTEX Portal (Tissue expression)FGF13
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92913   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92913  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92913
Splice isoforms : SwissVarQ92913
PhosPhoSitePlusQ92913
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (EBI)FGF13    Fibroblast_GF_fam    IL1/FGF   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
Conserved Domain (NCBI)FGF13
DMDM Disease mutations2258
Blocks (Seattle)FGF13
PDB (SRS)3HBW    4DCK    4JPZ   
PDB (PDBSum)3HBW    4DCK    4JPZ   
PDB (IMB)3HBW    4DCK    4JPZ   
PDB (RSDB)3HBW    4DCK    4JPZ   
Structural Biology KnowledgeBase3HBW    4DCK    4JPZ   
SCOP (Structural Classification of Proteins)3HBW    4DCK    4JPZ   
CATH (Classification of proteins structures)3HBW    4DCK    4JPZ   
SuperfamilyQ92913
Human Protein AtlasENSG00000129682
Peptide AtlasQ92913
HPRD02090
IPIIPI00024251   IPI00066574   IPI00552068   IPI00915358   IPI00552653   IPI00915279   IPI00644841   
Protein Interaction databases
DIP (DOE-UCLA)Q92913
IntAct (EBI)Q92913
FunCoupENSG00000129682
BioGRIDFGF13
STRING (EMBL)FGF13
ZODIACFGF13
Ontologies - Pathways
QuickGOQ92913
Ontology : AmiGOMAPK cascade  neuron migration  protein binding  extracellular region  nucleus  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  microtubule  plasma membrane  sodium ion transport  negative regulation of microtubule depolymerization  signal transduction  cell-cell signaling  nervous system development  learning  memory  microtubule binding  growth factor activity  intercalated disc  lateral plasma membrane  sodium channel regulator activity  sodium channel regulator activity  hippocampus development  cerebral cortex cell migration  filopodium  protein kinase activator activity  axon  dendrite  growth cone  activation of protein kinase activity  neuron projection  ion channel binding  establishment of neuroblast polarity  microtubule polymerization  beta-tubulin binding  negative regulation of collateral sprouting  protein localization to plasma membrane  regulation of cardiac muscle cell action potential involved in regulation of contraction  response to odorant  
Ontology : EGO-EBIMAPK cascade  neuron migration  protein binding  extracellular region  nucleus  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  microtubule  plasma membrane  sodium ion transport  negative regulation of microtubule depolymerization  signal transduction  cell-cell signaling  nervous system development  learning  memory  microtubule binding  growth factor activity  intercalated disc  lateral plasma membrane  sodium channel regulator activity  sodium channel regulator activity  hippocampus development  cerebral cortex cell migration  filopodium  protein kinase activator activity  axon  dendrite  growth cone  activation of protein kinase activity  neuron projection  ion channel binding  establishment of neuroblast polarity  microtubule polymerization  beta-tubulin binding  negative regulation of collateral sprouting  protein localization to plasma membrane  regulation of cardiac muscle cell action potential involved in regulation of contraction  response to odorant  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    PI3K-Akt signaling pathway    Regulation of actin cytoskeleton    Pathways in cancer    Proteoglycans in cancer    Melanoma   
NDEx NetworkFGF13
Atlas of Cancer Signalling NetworkFGF13
Wikipedia pathwaysFGF13
Orthology - Evolution
OrthoDB2258
GeneTree (enSembl)ENSG00000129682
Phylogenetic Trees/Animal Genes : TreeFamFGF13
HOVERGENQ92913
HOGENOMQ92913
Homologs : HomoloGeneFGF13
Homology/Alignments : Family Browser (UCSC)FGF13
Gene fusions - Rearrangements
Fusion : MitelmanFGF13/DACH2 [Xq26.3/Xq21.2]  
Fusion : MitelmanFGF13/SGK1 [Xq26.3/6q23.2]  [t(X;6)(q27;q23)]  
Fusion: TCGAFGF13 Xq26.3 AL109749.1 LUAD
Fusion: TCGAFGF13 Xq26.3 DACH2 Xq21.2 LUAD
Fusion: TCGAFGF13 Xq26.3 NLRP3 1q44 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGF13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGF13
dbVarFGF13
ClinVarFGF13
1000_GenomesFGF13 
Exome Variant ServerFGF13
ExAC (Exome Aggregation Consortium)FGF13 (select the gene name)
Genetic variants : HAPMAP2258
Genomic Variants (DGV)FGF13 [DGVbeta]
DECIPHERFGF13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFGF13 
Mutations
ICGC Data PortalFGF13 
TCGA Data PortalFGF13 
Broad Tumor PortalFGF13
OASIS PortalFGF13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGF13  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFGF13
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FGF13
DgiDB (Drug Gene Interaction Database)FGF13
DoCM (Curated mutations)FGF13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGF13 (select a term)
intoGenFGF13
Cancer3DFGF13(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300070   
Orphanet
MedgenFGF13
Genetic Testing Registry FGF13
NextProtQ92913 [Medical]
TSGene2258
GENETestsFGF13
Target ValidationFGF13
Huge Navigator FGF13 [HugePedia]
snp3D : Map Gene to Disease2258
BioCentury BCIQFGF13
ClinGenFGF13
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2258
Chemical/Pharm GKB GenePA28109
Clinical trialFGF13
Miscellaneous
canSAR (ICR)FGF13 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGF13
EVEXFGF13
GoPubMedFGF13
iHOPFGF13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:13 CEST 2017

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