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FGF14 (fibroblast growth factor 14)

Identity

Alias_symbol (synonym)FHF4
SCA27
Other aliasFGF-14
FHF-4
HGNC (Hugo) FGF14
LocusID (NCBI) 2259
Atlas_Id 40554
Location 13q33.1  [Link to chromosome band 13q33]
Location_base_pair Starts at 101720855 and ends at 102310686 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TMTC4 (13q32.3) / FGF14 (13q33.1)UQCRQ (5q31.1) / FGF14 (13q33.1)TMTC4 13q32.3 / FGF14 13q33.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGF14   3671
Cards
Entrez_Gene (NCBI)FGF14  2259  fibroblast growth factor 14
AliasesFGF-14; FHF-4; FHF4; SCA27
GeneCards (Weizmann)FGF14
Ensembl hg19 (Hinxton)ENSG00000102466 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102466 [Gene_View]  chr13:101720855-102310686 [Contig_View]  FGF14 [Vega]
ICGC DataPortalENSG00000102466
TCGA cBioPortalFGF14
AceView (NCBI)FGF14
Genatlas (Paris)FGF14
WikiGenes2259
SOURCE (Princeton)FGF14
Genetics Home Reference (NIH)FGF14
Genomic and cartography
GoldenPath hg38 (UCSC)FGF14  -     chr13:101720855-102310686 -  13q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FGF14  -     13q33.1   [Description]    (hg19-Feb_2009)
EnsemblFGF14 - 13q33.1 [CytoView hg19]  FGF14 - 13q33.1 [CytoView hg38]
Mapping of homologs : NCBIFGF14 [Mapview hg19]  FGF14 [Mapview hg38]
OMIM601515   609307   
Gene and transcription
Genbank (Entrez)AY188178 BC100920 BC100921 BC100922 U66200
RefSeq transcript (Entrez)
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FGF14
Cluster EST : UnigeneHs.508616 [ NCBI ]
CGAP (NCI)Hs.508616
Alternative Splicing GalleryENSG00000102466
Gene ExpressionFGF14 [ NCBI-GEO ]   FGF14 [ EBI - ARRAY_EXPRESS ]   FGF14 [ SEEK ]   FGF14 [ MEM ]
Gene Expression Viewer (FireBrowse)FGF14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2259
GTEX Portal (Tissue expression)FGF14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92915   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92915  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92915
Splice isoforms : SwissVarQ92915
PhosPhoSitePlusQ92915
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (EBI)FGF14    Fibroblast_GF_fam    IL1/FGF   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
Conserved Domain (NCBI)FGF14
DMDM Disease mutations2259
Blocks (Seattle)FGF14
SuperfamilyQ92915
Human Protein AtlasENSG00000102466
Peptide AtlasQ92915
HPRD03305
IPIIPI00024253   IPI00329411   
Protein Interaction databases
DIP (DOE-UCLA)Q92915
IntAct (EBI)Q92915
FunCoupENSG00000102466
BioGRIDFGF14
STRING (EMBL)FGF14
ZODIACFGF14
Ontologies - Pathways
QuickGOQ92915
Ontology : AmiGOprotein binding  extracellular region  nucleus  signal transduction  cell-cell signaling  nervous system development  growth factor activity  regulation of synaptic plasticity  regulation of postsynaptic membrane potential  positive regulation of high voltage-gated calcium channel activity  regulation of synaptic vesicle recycling  
Ontology : EGO-EBIprotein binding  extracellular region  nucleus  signal transduction  cell-cell signaling  nervous system development  growth factor activity  regulation of synaptic plasticity  regulation of postsynaptic membrane potential  positive regulation of high voltage-gated calcium channel activity  regulation of synaptic vesicle recycling  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    PI3K-Akt signaling pathway    Regulation of actin cytoskeleton    Pathways in cancer    Proteoglycans in cancer    Melanoma   
NDEx NetworkFGF14
Atlas of Cancer Signalling NetworkFGF14
Wikipedia pathwaysFGF14
Orthology - Evolution
OrthoDB2259
GeneTree (enSembl)ENSG00000102466
Phylogenetic Trees/Animal Genes : TreeFamFGF14
HOVERGENQ92915
HOGENOMQ92915
Homologs : HomoloGeneFGF14
Homology/Alignments : Family Browser (UCSC)FGF14
Gene fusions - Rearrangements
Fusion : MitelmanTMTC4/FGF14 [13q32.3/13q33.1]  [t(13;13)(q32;q33)]  
Fusion: TCGATMTC4 13q32.3 FGF14 13q33.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGF14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGF14
dbVarFGF14
ClinVarFGF14
1000_GenomesFGF14 
Exome Variant ServerFGF14
ExAC (Exome Aggregation Consortium)FGF14 (select the gene name)
Genetic variants : HAPMAP2259
Genomic Variants (DGV)FGF14 [DGVbeta]
DECIPHERFGF14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFGF14 
Mutations
ICGC Data PortalFGF14 
TCGA Data PortalFGF14 
Broad Tumor PortalFGF14
OASIS PortalFGF14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGF14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFGF14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch FGF14
DgiDB (Drug Gene Interaction Database)FGF14
DoCM (Curated mutations)FGF14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGF14 (select a term)
intoGenFGF14
Cancer3DFGF14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601515    609307   
Orphanet13781   
MedgenFGF14
Genetic Testing Registry FGF14
NextProtQ92915 [Medical]
TSGene2259
GENETestsFGF14
Target ValidationFGF14
Huge Navigator FGF14 [HugePedia]
snp3D : Map Gene to Disease2259
BioCentury BCIQFGF14
ClinGenFGF14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2259
Chemical/Pharm GKB GenePA28110
Clinical trialFGF14
Miscellaneous
canSAR (ICR)FGF14 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGF14
EVEXFGF14
GoPubMedFGF14
iHOPFGF14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:13 CEST 2017

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