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FGF16 (fibroblast growth factor 16)

Identity

Alias_namesMF4
metacarpal 4-5 fusion
Other aliasFGF-16
HGNC (Hugo) FGF16
LocusID (NCBI) 8823
Atlas_Id 40555
Location Xq21.1  [Link to chromosome band Xq21]
Location_base_pair Starts at 77447675 and ends at 77456522 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGF16   3672
Cards
Entrez_Gene (NCBI)FGF16  8823  fibroblast growth factor 16
AliasesFGF-16; MF4
GeneCards (Weizmann)FGF16
Ensembl hg19 (Hinxton)ENSG00000196468 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196468 [Gene_View]  chrX:77447675-77456522 [Contig_View]  FGF16 [Vega]
ICGC DataPortalENSG00000196468
TCGA cBioPortalFGF16
AceView (NCBI)FGF16
Genatlas (Paris)FGF16
WikiGenes8823
SOURCE (Princeton)FGF16
Genetics Home Reference (NIH)FGF16
Genomic and cartography
GoldenPath hg38 (UCSC)FGF16  -     chrX:77447675-77456522 +  Xq21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FGF16  -     Xq21.1   [Description]    (hg19-Feb_2009)
EnsemblFGF16 - Xq21.1 [CytoView hg19]  FGF16 - Xq21.1 [CytoView hg38]
Mapping of homologs : NCBIFGF16 [Mapview hg19]  FGF16 [Mapview hg38]
OMIM300827   309630   
Gene and transcription
Genbank (Entrez)AB009391 BC148639 BC153196
RefSeq transcript (Entrez)NM_003868
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FGF16
Cluster EST : UnigeneHs.666364 [ NCBI ]
CGAP (NCI)Hs.666364
Alternative Splicing GalleryENSG00000196468
Gene ExpressionFGF16 [ NCBI-GEO ]   FGF16 [ EBI - ARRAY_EXPRESS ]   FGF16 [ SEEK ]   FGF16 [ MEM ]
Gene Expression Viewer (FireBrowse)FGF16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8823
GTEX Portal (Tissue expression)FGF16
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43320   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43320  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43320
Splice isoforms : SwissVarO43320
PhosPhoSitePlusO43320
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (EBI)FGF16    Fibroblast_GF_fam    IL1/FGF   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
Conserved Domain (NCBI)FGF16
DMDM Disease mutations8823
Blocks (Seattle)FGF16
SuperfamilyO43320
Human Protein AtlasENSG00000196468
Peptide AtlasO43320
HPRD04764
IPIIPI00011975   
Protein Interaction databases
DIP (DOE-UCLA)O43320
IntAct (EBI)O43320
FunCoupENSG00000196468
BioGRIDFGF16
STRING (EMBL)FGF16
ZODIACFGF16
Ontologies - Pathways
QuickGOO43320
Ontology : AmiGOMAPK cascade  regulation of endothelial cell proliferation  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  fibroblast growth factor receptor binding  extracellular region  extracellular space  intracellular  signal transduction  cell-cell signaling  growth factor activity  metabolic process  fibroblast growth factor receptor signaling pathway  response to temperature stimulus  animal organ morphogenesis  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  phosphatidylinositol-3-phosphate biosynthetic process  regulation of MAP kinase activity  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of brown fat cell proliferation  regulation of sprouting angiogenesis  positive regulation of endothelial cell chemotaxis to fibroblast growth factor  
Ontology : EGO-EBIMAPK cascade  regulation of endothelial cell proliferation  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  fibroblast growth factor receptor binding  extracellular region  extracellular space  intracellular  signal transduction  cell-cell signaling  growth factor activity  metabolic process  fibroblast growth factor receptor signaling pathway  response to temperature stimulus  animal organ morphogenesis  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  phosphatidylinositol-3-phosphate biosynthetic process  regulation of MAP kinase activity  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of brown fat cell proliferation  regulation of sprouting angiogenesis  positive regulation of endothelial cell chemotaxis to fibroblast growth factor  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    PI3K-Akt signaling pathway    Regulation of actin cytoskeleton    Pathways in cancer    Proteoglycans in cancer    Melanoma   
NDEx NetworkFGF16
Atlas of Cancer Signalling NetworkFGF16
Wikipedia pathwaysFGF16
Orthology - Evolution
OrthoDB8823
GeneTree (enSembl)ENSG00000196468
Phylogenetic Trees/Animal Genes : TreeFamFGF16
HOVERGENO43320
HOGENOMO43320
Homologs : HomoloGeneFGF16
Homology/Alignments : Family Browser (UCSC)FGF16
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGF16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGF16
dbVarFGF16
ClinVarFGF16
1000_GenomesFGF16 
Exome Variant ServerFGF16
ExAC (Exome Aggregation Consortium)FGF16 (select the gene name)
Genetic variants : HAPMAP8823
Genomic Variants (DGV)FGF16 [DGVbeta]
DECIPHERFGF16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFGF16 
Mutations
ICGC Data PortalFGF16 
TCGA Data PortalFGF16 
Broad Tumor PortalFGF16
OASIS PortalFGF16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGF16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFGF16
BioMutasearch FGF16
DgiDB (Drug Gene Interaction Database)FGF16
DoCM (Curated mutations)FGF16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGF16 (select a term)
intoGenFGF16
Cancer3DFGF16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300827    309630   
Orphanet2310   
MedgenFGF16
Genetic Testing Registry FGF16
NextProtO43320 [Medical]
TSGene8823
GENETestsFGF16
Target ValidationFGF16
Huge Navigator FGF16 [HugePedia]
snp3D : Map Gene to Disease8823
BioCentury BCIQFGF16
ClinGenFGF16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8823
Chemical/Pharm GKB GenePA28111
Clinical trialFGF16
Miscellaneous
canSAR (ICR)FGF16 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGF16
EVEXFGF16
GoPubMedFGF16
iHOPFGF16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:13 CEST 2017

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