Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FGF20 (fibroblast growth factor 20)

Identity

Other aliasFGF-20
RHDA2
HGNC (Hugo) FGF20
LocusID (NCBI) 26281
Atlas_Id 40559
Location 8p22  [Link to chromosome band 8p22]
Location_base_pair Starts at 16992825 and ends at 17002165 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGF20   3677
Cards
Entrez_Gene (NCBI)FGF20  26281  fibroblast growth factor 20
AliasesFGF-20; RHDA2
GeneCards (Weizmann)FGF20
Ensembl hg19 (Hinxton)ENSG00000078579 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078579 [Gene_View]  chr8:16992825-17002165 [Contig_View]  FGF20 [Vega]
ICGC DataPortalENSG00000078579
TCGA cBioPortalFGF20
AceView (NCBI)FGF20
Genatlas (Paris)FGF20
WikiGenes26281
SOURCE (Princeton)FGF20
Genetics Home Reference (NIH)FGF20
Genomic and cartography
GoldenPath hg38 (UCSC)FGF20  -     chr8:16992825-17002165 -  8p22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FGF20  -     8p22   [Description]    (hg19-Feb_2009)
EnsemblFGF20 - 8p22 [CytoView hg19]  FGF20 - 8p22 [CytoView hg38]
Mapping of homologs : NCBIFGF20 [Mapview hg19]  FGF20 [Mapview hg38]
OMIM605558   615721   
Gene and transcription
Genbank (Entrez)AB030648 AB044277 BC096720 BC098128 BC098153
RefSeq transcript (Entrez)NM_019851
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FGF20
Cluster EST : UnigeneHs.199905 [ NCBI ]
CGAP (NCI)Hs.199905
Alternative Splicing GalleryENSG00000078579
Gene ExpressionFGF20 [ NCBI-GEO ]   FGF20 [ EBI - ARRAY_EXPRESS ]   FGF20 [ SEEK ]   FGF20 [ MEM ]
Gene Expression Viewer (FireBrowse)FGF20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26281
GTEX Portal (Tissue expression)FGF20
Human Protein AtlasENSG00000078579-FGF20 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP95   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP95  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP95
Splice isoforms : SwissVarQ9NP95
PhosPhoSitePlusQ9NP95
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (EBI)FGF20    Fibroblast_GF_fam    IL1/FGF   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
Conserved Domain (NCBI)FGF20
DMDM Disease mutations26281
Blocks (Seattle)FGF20
PDB (SRS)3F1R   
PDB (PDBSum)3F1R   
PDB (IMB)3F1R   
PDB (RSDB)3F1R   
Structural Biology KnowledgeBase3F1R   
SCOP (Structural Classification of Proteins)3F1R   
CATH (Classification of proteins structures)3F1R   
SuperfamilyQ9NP95
Human Protein Atlas [tissue]ENSG00000078579-FGF20 [tissue]
Peptide AtlasQ9NP95
HPRD05709
IPIIPI00014608   IPI00607609   IPI00980011   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP95
IntAct (EBI)Q9NP95
FunCoupENSG00000078579
BioGRIDFGF20
STRING (EMBL)FGF20
ZODIACFGF20
Ontologies - Pathways
QuickGOQ9NP95
Ontology : AmiGOMAPK cascade  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  receptor binding  fibroblast growth factor receptor binding  extracellular region  intracellular  signal transduction  cell-cell signaling  growth factor activity  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  regulation of dopamine secretion  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  phosphatidylinositol-3-phosphate biosynthetic process  heparan sulfate proteoglycan binding  negative regulation of neuron apoptotic process  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  regulation of cardiac muscle cell proliferation  inner ear receptor cell differentiation  positive regulation of ERK1 and ERK2 cascade  receptor-receptor interaction  positive regulation of dopaminergic neuron differentiation  
Ontology : EGO-EBIMAPK cascade  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  receptor binding  fibroblast growth factor receptor binding  extracellular region  intracellular  signal transduction  cell-cell signaling  growth factor activity  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  regulation of dopamine secretion  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  phosphatidylinositol-3-phosphate biosynthetic process  heparan sulfate proteoglycan binding  negative regulation of neuron apoptotic process  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  regulation of cardiac muscle cell proliferation  inner ear receptor cell differentiation  positive regulation of ERK1 and ERK2 cascade  receptor-receptor interaction  positive regulation of dopaminergic neuron differentiation  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    PI3K-Akt signaling pathway    Regulation of actin cytoskeleton    Pathways in cancer    Proteoglycans in cancer    Melanoma   
NDEx NetworkFGF20
Atlas of Cancer Signalling NetworkFGF20
Wikipedia pathwaysFGF20
Orthology - Evolution
OrthoDB26281
GeneTree (enSembl)ENSG00000078579
Phylogenetic Trees/Animal Genes : TreeFamFGF20
HOVERGENQ9NP95
HOGENOMQ9NP95
Homologs : HomoloGeneFGF20
Homology/Alignments : Family Browser (UCSC)FGF20
Gene fusions - Rearrangements
Tumor Fusion PortalFGF20
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGF20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGF20
dbVarFGF20
ClinVarFGF20
1000_GenomesFGF20 
Exome Variant ServerFGF20
ExAC (Exome Aggregation Consortium)ENSG00000078579
GNOMAD BrowserENSG00000078579
Genetic variants : HAPMAP26281
Genomic Variants (DGV)FGF20 [DGVbeta]
DECIPHERFGF20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFGF20 
Mutations
ICGC Data PortalFGF20 
TCGA Data PortalFGF20 
Broad Tumor PortalFGF20
OASIS PortalFGF20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGF20  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFGF20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FGF20
DgiDB (Drug Gene Interaction Database)FGF20
DoCM (Curated mutations)FGF20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGF20 (select a term)
intoGenFGF20
Cancer3DFGF20(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605558    615721   
Orphanet2656   
DisGeNETFGF20
MedgenFGF20
Genetic Testing Registry FGF20
NextProtQ9NP95 [Medical]
TSGene26281
GENETestsFGF20
Target ValidationFGF20
Huge Navigator FGF20 [HugePedia]
snp3D : Map Gene to Disease26281
BioCentury BCIQFGF20
ClinGenFGF20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26281
Chemical/Pharm GKB GenePA28116
Clinical trialFGF20
Miscellaneous
canSAR (ICR)FGF20 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGF20
EVEXFGF20
GoPubMedFGF20
iHOPFGF20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:13:18 CET 2017

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