Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FGF5 (fibroblast growth factor 5)

Identity

Other aliasHBGF-5
Smag-82
TCMGLY
HGNC (Hugo) FGF5
LocusID (NCBI) 2250
Atlas_Id 40563
Location 4q21.21  [Link to chromosome band 4q21]
Location_base_pair Starts at 81189419 and ends at 81212171 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FGF5 (4q21.21) / HLA-DRB1 (6p21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FGF5   3683
Cards
Entrez_Gene (NCBI)FGF5  2250  fibroblast growth factor 5
AliasesHBGF-5; Smag-82; TCMGLY
GeneCards (Weizmann)FGF5
Ensembl hg19 (Hinxton)ENSG00000138675 [Gene_View]  chr4:81189419-81212171 [Contig_View]  FGF5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000138675 [Gene_View]  chr4:81189419-81212171 [Contig_View]  FGF5 [Vega]
ICGC DataPortalENSG00000138675
TCGA cBioPortalFGF5
AceView (NCBI)FGF5
Genatlas (Paris)FGF5
WikiGenes2250
SOURCE (Princeton)FGF5
Genetics Home Reference (NIH)FGF5
Genomic and cartography
GoldenPath hg19 (UCSC)FGF5  -     chr4:81189419-81212171 +  4q21.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FGF5  -     4q21.21   [Description]    (hg38-Dec_2013)
EnsemblFGF5 - 4q21.21 [CytoView hg19]  FGF5 - 4q21.21 [CytoView hg38]
Mapping of homologs : NCBIFGF5 [Mapview hg19]  FGF5 [Mapview hg38]
OMIM165190   190330   
Gene and transcription
Genbank (Entrez)AA461028 AB016517 AF171928 AF355187 AF535149
RefSeq transcript (Entrez)NM_001291812 NM_004464 NM_033143
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_029501 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)FGF5
Cluster EST : UnigeneHs.37055 [ NCBI ]
CGAP (NCI)Hs.37055
Alternative Splicing GalleryENSG00000138675
Gene ExpressionFGF5 [ NCBI-GEO ]   FGF5 [ EBI - ARRAY_EXPRESS ]   FGF5 [ SEEK ]   FGF5 [ MEM ]
Gene Expression Viewer (FireBrowse)FGF5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2250
GTEX Portal (Tissue expression)FGF5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12034   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP12034  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12034
Splice isoforms : SwissVarP12034
PhosPhoSitePlusP12034
Domaine pattern : Prosite (Expaxy)HBGF_FGF (PS00247)   
Domains : Interpro (EBI)Cytokine_IL1-like    FGF5    Fibroblast_GF_fam    IL-1_fam/FGF_fam   
Domain families : Pfam (Sanger)FGF (PF00167)   
Domain families : Pfam (NCBI)pfam00167   
Domain families : Smart (EMBL)FGF (SM00442)  
Conserved Domain (NCBI)FGF5
DMDM Disease mutations2250
Blocks (Seattle)FGF5
SuperfamilyP12034
Human Protein AtlasENSG00000138675
Peptide AtlasP12034
HPRD01307
IPIIPI00295390   IPI01022135   IPI00036489   IPI00011879   IPI00966639   
Protein Interaction databases
DIP (DOE-UCLA)P12034
IntAct (EBI)P12034
FunCoupENSG00000138675
BioGRIDFGF5
STRING (EMBL)FGF5
ZODIACFGF5
Ontologies - Pathways
QuickGOP12034
Ontology : AmiGOMAPK cascade  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  fibroblast growth factor receptor binding  extracellular region  extracellular space  intracellular  cell-cell signaling  nervous system development  growth factor activity  cell proliferation  positive regulation of cell proliferation  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  glial cell differentiation  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  signal transduction involved in regulation of gene expression  phosphatidylinositol-3-phosphate biosynthetic process  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of cell division  
Ontology : EGO-EBIMAPK cascade  protein tyrosine kinase activity  Ras guanyl-nucleotide exchange factor activity  fibroblast growth factor receptor binding  extracellular region  extracellular space  intracellular  cell-cell signaling  nervous system development  growth factor activity  cell proliferation  positive regulation of cell proliferation  positive regulation of cell proliferation  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  glial cell differentiation  regulation of phosphatidylinositol 3-kinase signaling  1-phosphatidylinositol-3-kinase activity  peptidyl-tyrosine phosphorylation  signal transduction involved in regulation of gene expression  phosphatidylinositol-3-phosphate biosynthetic process  positive regulation of GTPase activity  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of cell division  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Rap1 signaling pathway    PI3K-Akt signaling pathway    Regulation of actin cytoskeleton    Pathways in cancer    Proteoglycans in cancer    Melanoma   
NDEx NetworkFGF5
Atlas of Cancer Signalling NetworkFGF5
Wikipedia pathwaysFGF5
Orthology - Evolution
OrthoDB2250
GeneTree (enSembl)ENSG00000138675
Phylogenetic Trees/Animal Genes : TreeFamFGF5
HOVERGENP12034
HOGENOMP12034
Homologs : HomoloGeneFGF5
Homology/Alignments : Family Browser (UCSC)FGF5
Gene fusions - Rearrangements
Fusion Cancer (Beijing)FGF5 [4q21.21]  -  HLA-DRB1 [6p21.32]  [FUSC002735]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGF5
dbVarFGF5
ClinVarFGF5
1000_GenomesFGF5 
Exome Variant ServerFGF5
ExAC (Exome Aggregation Consortium)FGF5 (select the gene name)
Genetic variants : HAPMAP2250
Genomic Variants (DGV)FGF5 [DGVbeta]
DECIPHER (Syndromes)4:81189419-81212171  ENSG00000138675
CONAN: Copy Number AnalysisFGF5 
Mutations
ICGC Data PortalFGF5 
TCGA Data PortalFGF5 
Broad Tumor PortalFGF5
OASIS PortalFGF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGF5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFGF5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FGF5
DgiDB (Drug Gene Interaction Database)FGF5
DoCM (Curated mutations)FGF5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FGF5 (select a term)
intoGenFGF5
Cancer3DFGF5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM165190    190330   
Orphanet23034   
MedgenFGF5
Genetic Testing Registry FGF5
NextProtP12034 [Medical]
TSGene2250
GENETestsFGF5
Huge Navigator FGF5 [HugePedia]
snp3D : Map Gene to Disease2250
BioCentury BCIQFGF5
ClinGenFGF5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2250
Chemical/Pharm GKB GenePA28122
Clinical trialFGF5
Miscellaneous
canSAR (ICR)FGF5 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFGF5
EVEXFGF5
GoPubMedFGF5
iHOPFGF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:06:08 CET 2017

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