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FGG (fibrinogen gamma chain)

Identity

Other names-
HGNC (Hugo) FGG
LocusID (NCBI) 2266
Location 4q31.3
Location_base_pair Starts at 155525286 and ends at 155533902 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FGG   3694
Cards
Entrez_Gene (NCBI)FGG  2266  fibrinogen gamma chain
GeneCards (Weizmann)FGG
Ensembl (Hinxton)ENSG00000171557 [Gene_View]  chr4:155525286-155533902 [Contig_View]  FGG [Vega]
ICGC DataPortalENSG00000171557
cBioPortalFGG
AceView (NCBI)FGG
Genatlas (Paris)FGG
WikiGenes2266
SOURCE (Princeton)NM_000509 NM_021870
Genomic and cartography
GoldenPath (UCSC)FGG  -  4q31.3   chr4:155525286-155533902 -  4q31.3   [Description]    (hg19-Feb_2009)
EnsemblFGG - 4q31.3 [CytoView]
Mapping of homologs : NCBIFGG [Mapview]
OMIM134850   
Gene and transcription
Genbank (Entrez)AA936960 AI808530 AK289422 AK290824 AL531173
RefSeq transcript (Entrez)NM_000509 NM_021870
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NG_008834 NT_016354 NW_001838921 NW_004929320
Consensus coding sequences : CCDS (NCBI)FGG
Cluster EST : UnigeneHs.727584 [ NCBI ]
CGAP (NCI)Hs.727584
Alternative Splicing : Fast-db (Paris)GSHG0023603
Alternative Splicing GalleryENSG00000171557
Gene ExpressionFGG [ NCBI-GEO ]     FGG [ SEEK ]   FGG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02679 (Uniprot)
NextProtP02679  [Medical]
With graphics : InterProP02679
Splice isoforms : SwissVarP02679 (Swissvar)
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)Fibrinogen_a/b/g_C_1 [organisation]   Fibrinogen_a/b/g_C_2 [organisation]   Fibrinogen_a/b/g_C_dom [organisation]   Fibrinogen_a/b/g_coil_dom [organisation]   Fibrinogen_CS [organisation]  
Related proteins : CluSTrP02679
Domain families : Pfam (Sanger)Fib_alpha (PF08702)    Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam08702    pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
DMDM Disease mutations2266
Blocks (Seattle)P02679
PDB (SRS)1DUG    1FIB    1FIC    1FID    1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2FIB    2H43    2HLO    2HOD    2HPC    2HWL    2OYH    2OYI    2Q9I    2VDO    2VDP    2VDQ    2VDR    2VR3    2XNX    2XNY    2Y7L    2Z4E    3BVH    3E1I    3FIB    3GHG    3H32    3HUS    4B60   
PDB (PDBSum)1DUG    1FIB    1FIC    1FID    1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2FIB    2H43    2HLO    2HOD    2HPC    2HWL    2OYH    2OYI    2Q9I    2VDO    2VDP    2VDQ    2VDR    2VR3    2XNX    2XNY    2Y7L    2Z4E    3BVH    3E1I    3FIB    3GHG    3H32    3HUS    4B60   
PDB (IMB)1DUG    1FIB    1FIC    1FID    1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2FIB    2H43    2HLO    2HOD    2HPC    2HWL    2OYH    2OYI    2Q9I    2VDO    2VDP    2VDQ    2VDR    2VR3    2XNX    2XNY    2Y7L    2Z4E    3BVH    3E1I    3FIB    3GHG    3H32    3HUS    4B60   
PDB (RSDB)1DUG    1FIB    1FIC    1FID    1FZA    1FZB    1FZC    1FZE    1FZF    1FZG    1LT9    1LTJ    1N86    1N8E    1RE3    1RE4    1RF0    1RF1    2A45    2FFD    2FIB    2H43    2HLO    2HOD    2HPC    2HWL    2OYH    2OYI    2Q9I    2VDO    2VDP    2VDQ    2VDR    2VR3    2XNX    2XNY    2Y7L    2Z4E    3BVH    3E1I    3FIB    3GHG    3H32    3HUS    4B60   
Human Protein AtlasENSG00000171557 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP02679
HPRD00621
IPIIPI00021891   IPI00219713   IPI00877792   IPI00877703   IPI00411626   IPI00877625   
Protein Interaction databases
DIP (DOE-UCLA)P02679
IntAct (EBI)P02679
FunCoupENSG00000171557
BioGRIDFGG
InParanoidP02679
Interologous Interaction database P02679
IntegromeDBFGG
STRING (EMBL)FGG
Ontologies - Pathways
Ontology : AmiGOplatelet degranulation  receptor binding  structural molecule activity  extracellular region  fibrinogen complex  extracellular space  plasma membrane  cell cortex  cell-matrix adhesion  signal transduction  blood coagulation  external side of plasma membrane  cell surface  platelet activation  extracellular matrix organization  protein binding, bridging  platelet alpha granule  platelet alpha granule lumen  positive regulation of heterotypic cell-cell adhesion  cellular protein complex assembly  positive regulation of vasoconstriction  positive regulation of exocytosis  metal ion binding  positive regulation of protein secretion  cell adhesion molecule binding  protein polymerization  response to calcium ion  extracellular vesicular exosome  positive regulation of ERK1 and ERK2 cascade  platelet aggregation  blood microparticle  positive regulation of peptide hormone secretion  positive regulation of substrate adhesion-dependent cell spreading  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of endothelial cell apoptotic process  
Ontology : EGO-EBIplatelet degranulation  receptor binding  structural molecule activity  extracellular region  fibrinogen complex  extracellular space  plasma membrane  cell cortex  cell-matrix adhesion  signal transduction  blood coagulation  external side of plasma membrane  cell surface  platelet activation  extracellular matrix organization  protein binding, bridging  platelet alpha granule  platelet alpha granule lumen  positive regulation of heterotypic cell-cell adhesion  cellular protein complex assembly  positive regulation of vasoconstriction  positive regulation of exocytosis  metal ion binding  positive regulation of protein secretion  cell adhesion molecule binding  protein polymerization  response to calcium ion  extracellular vesicular exosome  positive regulation of ERK1 and ERK2 cascade  platelet aggregation  blood microparticle  positive regulation of peptide hormone secretion  positive regulation of substrate adhesion-dependent cell spreading  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of endothelial cell apoptotic process  
Pathways : BIOCARTAIntrinsic Prothrombin Activation Pathway [Genes]    Extrinsic Prothrombin Activation Pathway [Genes]    Acute Myocardial Infarction [Genes]    Fibrinolysis Pathway [Genes]   
Pathways : KEGGComplement and coagulation cascades    Staphylococcus aureus infection   
Protein Interaction DatabaseFGG
Wikipedia pathwaysFGG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FGG
snp3D : Map Gene to Disease2266
SNP (GeneSNP Utah)FGG
SNP : HGBaseFGG
Genetic variants : HAPMAPFGG
Exome VariantFGG
1000_GenomesFGG 
ICGC programENSG00000171557 
Somatic Mutations in Cancer : COSMICFGG 
CONAN: Copy Number AnalysisFGG 
Mutations and Diseases : HGMDFGG
Mutations and Diseases : intOGenFGG
Genomic VariantsFGG  FGG [DGVbeta]
dbVarFGG
ClinVarFGG
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM134850   
MedgenFGG
GENETestsFGG
Disease Genetic AssociationFGG
Huge Navigator FGG [HugePedia]  FGG [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneFGG
Homology/Alignments : Family Browser (UCSC)FGG
Phylogenetic Trees/Animal Genes : TreeFamFGG
Chemical/Protein Interactions : CTD2266
Chemical/Pharm GKB GenePA430
Clinical trialFGG
Cancer Resource (Charite)ENSG00000171557
Other databases
Probes
Litterature
PubMed219 Pubmed reference(s) in Entrez
CoreMineFGG
iHOPFGG
OncoSearchFGG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:46:57 CEST 2014

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