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FGL1 (fibrinogen like 1)

Identity

Alias (NCBI)HFREP1
HP-041
HPS
LFIRE-1
LFIRE1
HGNC (Hugo) FGL1
HGNC Alias symbHFREP-1
HPS
HGNC Alias namehepassocin
LocusID (NCBI) 2267
Atlas_Id 40571
Location 8p22  [Link to chromosome band 8p22]
Location_base_pair Starts at 17864391 and ends at 17895404 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTUS1 (8p22) / FGL1 (8p22)PCM1 (8p22) / FGL1 (8p22)MTUS1 8p22 / FGL1 8p22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FGL1   3695
Cards
Entrez_Gene (NCBI)FGL1    fibrinogen like 1
AliasesHFREP1; HP-041; HPS; LFIRE-1; 
LFIRE1
GeneCards (Weizmann)FGL1
Ensembl hg19 (Hinxton)ENSG00000104760 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104760 [Gene_View]  ENSG00000104760 [Sequence]  chr8:17864391-17895404 [Contig_View]  FGL1 [Vega]
ICGC DataPortalENSG00000104760
TCGA cBioPortalFGL1
AceView (NCBI)FGL1
Genatlas (Paris)FGL1
SOURCE (Princeton)FGL1
Genetics Home Reference (NIH)FGL1
Genomic and cartography
GoldenPath hg38 (UCSC)FGL1  -     chr8:17864391-17895404 -  8p22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FGL1  -     8p22   [Description]    (hg19-Feb_2009)
GoldenPathFGL1 - 8p22 [CytoView hg19]  FGL1 - 8p22 [CytoView hg38]
ImmunoBaseENSG00000104760
Genome Data Viewer NCBIFGL1 [Mapview hg19]  
OMIM605776   
Gene and transcription
Genbank (Entrez)AF042354 AF168954 AK225616 AK225619 AK289448
RefSeq transcript (Entrez)NM_004467 NM_147203 NM_201552 NM_201553
Consensus coding sequences : CCDS (NCBI)FGL1
Gene ExpressionFGL1 [ NCBI-GEO ]   FGL1 [ EBI - ARRAY_EXPRESS ]   FGL1 [ SEEK ]   FGL1 [ MEM ]
Gene Expression Viewer (FireBrowse)FGL1 [ Firebrowse - Broad ]
GenevisibleExpression of FGL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2267
GTEX Portal (Tissue expression)FGL1
Human Protein AtlasENSG00000104760-FGL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08830   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08830  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08830
PhosPhoSitePlusQ08830
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)Fibrinogen-like_C    Fibrinogen_a/b/g_C_dom    Fibrinogen_CS   
Domain families : Pfam (Sanger)Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
Conserved Domain (NCBI)FGL1
SuperfamilyQ08830
AlphaFold pdb e-kbQ08830   
Human Protein Atlas [tissue]ENSG00000104760-FGL1 [tissue]
HPRD09312
Protein Interaction databases
DIP (DOE-UCLA)Q08830
IntAct (EBI)Q08830
BioGRIDFGL1
STRING (EMBL)FGL1
ZODIACFGL1
Ontologies - Pathways
QuickGOQ08830
Ontology : AmiGOadaptive immune response  signaling receptor binding  protein binding  extracellular region  fibrinogen complex  extracellular space  regulation of immune response  regulation of immune response  negative regulation of T cell activation  negative regulation of T cell activation  collagen-containing extracellular matrix  hepatocyte proliferation  
Ontology : EGO-EBIadaptive immune response  signaling receptor binding  protein binding  extracellular region  fibrinogen complex  extracellular space  regulation of immune response  regulation of immune response  negative regulation of T cell activation  negative regulation of T cell activation  collagen-containing extracellular matrix  hepatocyte proliferation  
NDEx NetworkFGL1
Atlas of Cancer Signalling NetworkFGL1
Wikipedia pathwaysFGL1
Orthology - Evolution
OrthoDB2267
GeneTree (enSembl)ENSG00000104760
Phylogenetic Trees/Animal Genes : TreeFamFGL1
Homologs : HomoloGeneFGL1
Homology/Alignments : Family Browser (UCSC)FGL1
Gene fusions - Rearrangements
Fusion : QuiverFGL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFGL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FGL1
dbVarFGL1
ClinVarFGL1
MonarchFGL1
1000_GenomesFGL1 
Exome Variant ServerFGL1
GNOMAD BrowserENSG00000104760
Varsome BrowserFGL1
ACMGFGL1 variants
VarityQ08830
Genomic Variants (DGV)FGL1 [DGVbeta]
DECIPHERFGL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFGL1 
Mutations
ICGC Data PortalFGL1 
TCGA Data PortalFGL1 
Broad Tumor PortalFGL1
OASIS PortalFGL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFGL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFGL1
Mutations and Diseases : HGMDFGL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFGL1
DgiDB (Drug Gene Interaction Database)FGL1
DoCM (Curated mutations)FGL1
CIViC (Clinical Interpretations of Variants in Cancer)FGL1
Cancer3DFGL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605776   
Orphanet
DisGeNETFGL1
MedgenFGL1
Genetic Testing Registry FGL1
NextProtQ08830 [Medical]
GENETestsFGL1
Target ValidationFGL1
Huge Navigator FGL1 [HugePedia]
ClinGenFGL1
Clinical trials, drugs, therapy
MyCancerGenomeFGL1
Protein Interactions : CTDFGL1
Pharm GKB GenePA28133
PharosQ08830
Clinical trialFGL1
Miscellaneous
canSAR (ICR)FGL1
HarmonizomeFGL1
DataMed IndexFGL1
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFGL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:09:29 CEST 2021

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