Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FHL1 (four and a half LIM domains 1)

Identity

Other namesFHL-1
FHL1A
FHL1B
FLH1A
KYOT
SLIM
SLIM-1
SLIM1
SLIMMER
XMPMA
HGNC (Hugo) FHL1
LocusID (NCBI) 2273
Location Xq26.3
Location_base_pair Starts at 135279055 and ends at 135293518 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FHL1   3702
Cards
Entrez_Gene (NCBI)FHL1  2273  four and a half LIM domains 1
GeneCards (Weizmann)FHL1
Ensembl (Hinxton)ENSG00000022267 [Gene_View]  chrX:135279055-135293518 [Contig_View]  FHL1 [Vega]
ICGC DataPortalENSG00000022267
AceView (NCBI)FHL1
Genatlas (Paris)FHL1
WikiGenes2273
SOURCE (Princeton)NM_001159699 NM_001159700 NM_001159701 NM_001159702 NM_001159703 NM_001159704 NM_001167819 NM_001449
Genomic and cartography
GoldenPath (UCSC)FHL1  -  Xq26.3   chrX:135279055-135293518 +  Xq26.3   [Description]    (hg19-Feb_2009)
EnsemblFHL1 - Xq26.3 [CytoView]
Mapping of homologs : NCBIFHL1 [Mapview]
OMIM300163   300695   300696   300717   300718   
Gene and transcription
Genbank (Entrez)AF063002 AF098518 AF220153 AK091702 AK094024
RefSeq transcript (Entrez)NM_001159699 NM_001159700 NM_001159701 NM_001159702 NM_001159703 NM_001159704 NM_001167819 NM_001449
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_015895 NT_011786 NW_001842404 NW_004929446
Consensus coding sequences : CCDS (NCBI)FHL1
Cluster EST : UnigeneHs.435369 [ NCBI ]
CGAP (NCI)Hs.435369
Alternative Splicing : Fast-db (Paris)GSHG0031835
Alternative Splicing GalleryENSG00000022267
Gene ExpressionFHL1 [ NCBI-GEO ]     FHL1 [ SEEK ]   FHL1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13642 (Uniprot)
NextProtQ13642  [Medical]
With graphics : InterProQ13642
Splice isoforms : SwissVarQ13642 (Swissvar)
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Znf_LIM   
Related proteins : CluSTrQ13642
Domain families : Pfam (Sanger)LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00412   
Domain families : Smart (EMBL)LIM (SM00132)  
DMDM Disease mutations2273
Blocks (Seattle)Q13642
PDB (SRS)1X63    2CUP    2CUR    2EGQ   
PDB (PDBSum)1X63    2CUP    2CUR    2EGQ   
PDB (IMB)1X63    2CUP    2CUR    2EGQ   
PDB (RSDB)1X63    2CUP    2CUR    2EGQ   
Human Protein AtlasENSG00000022267
Peptide AtlasQ13642
HPRD02157
IPIIPI00647207   IPI00055606   IPI00922730   IPI00922769   IPI00902610   IPI00930706   IPI00029028   IPI00014398   IPI00645286   IPI00643324   IPI00644118   IPI00644668   IPI00641404   IPI00639828   
Protein Interaction databases
DIP (DOE-UCLA)Q13642
IntAct (EBI)Q13642
FunCoupENSG00000022267
BioGRIDFHL1
InParanoidQ13642
Interologous Interaction database Q13642
IntegromeDBFHL1
STRING (EMBL)FHL1
Ontologies - Pathways
Ontology : AmiGOregulation of membrane depolarization  molecular_function  protein binding  nucleus  cytoplasm  cytosol  plasma membrane  muscle organ development  zinc ion binding  organ morphogenesis  negative regulation of G2/M transition of mitotic cell cycle  cell differentiation  negative regulation of cell growth  positive regulation of potassium ion transport  ion channel binding  regulation of potassium ion transmembrane transporter activity  negative regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBIregulation of membrane depolarization  molecular_function  protein binding  nucleus  cytoplasm  cytosol  plasma membrane  muscle organ development  zinc ion binding  organ morphogenesis  negative regulation of G2/M transition of mitotic cell cycle  cell differentiation  negative regulation of cell growth  positive regulation of potassium ion transport  ion channel binding  regulation of potassium ion transmembrane transporter activity  negative regulation of G1/S transition of mitotic cell cycle  
Protein Interaction DatabaseFHL1
Wikipedia pathwaysFHL1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FHL1
SNP (GeneSNP Utah)FHL1
SNP : HGBaseFHL1
Genetic variants : HAPMAPFHL1
1000_GenomesFHL1 
ICGC programENSG00000022267 
CONAN: Copy Number AnalysisFHL1 
Somatic Mutations in Cancer : COSMICFHL1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Mutations and Diseases : HGMDFHL1
OMIM300163    300695    300696    300717    300718   
MedgenFHL1
GENETestsFHL1
Disease Genetic AssociationFHL1
Huge Navigator FHL1 [HugePedia]  FHL1 [HugeCancerGEM]
Genomic VariantsFHL1  FHL1 [DGVbeta]
Exome VariantFHL1
dbVarFHL1
ClinVarFHL1
snp3D : Map Gene to Disease2273
General knowledge
Homologs : HomoloGeneFHL1
Homology/Alignments : Family Browser (UCSC)FHL1
Phylogenetic Trees/Animal Genes : TreeFamFHL1
Chemical/Protein Interactions : CTD2273
Chemical/Pharm GKB GenePA28141
Clinical trialFHL1
Cancer Resource (Charite)ENSG00000022267
Other databases
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
CoreMineFHL1
iHOPFHL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 13 12:46:39 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.