Identity
HGNC
LOCATION
Xq26.3
LOCUSID
ALIAS
FCMSU,FHL-1,FHL1A,FHL1B,FLH1A,KYOT,RBMX1A,RBMX1B,SLIM,SLIM-1,SLIM1,SLIMMER,XMPMA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2273
MIM: 300163
HGNC: 3702
Ensembl: ENSG00000022267
Variants:
dbSNP: 2273
ClinVar: 2273
TCGA: ENSG00000022267
COSMIC: FHL1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Jak-STAT signaling pathway | KEGG | ko04630 |
| Jak-STAT signaling pathway | KEGG | hsa04630 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38324167 | 2024 | Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer. | 0 |
| 38324167 | 2024 | Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer. | 0 |
| 35142956 | 2023 | Immortalization-upregulated protein promotes pancreatic cancer progression by regulating NPM1/FHL1-mediated cell-cycle-checkpoint protein activity. | 2 |
| 36695131 | 2023 | FHL1 as a novel prognostic biomarker and correlation with immune infiltration levels in lung adenocarcinoma. | 1 |
| 36864287 | 2023 | Identification of novel FHL1 mutations associated with X-linked scapuloperoneal myopathy in unrelated Chinese patients. | 0 |
| 36881973 | 2023 | Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells. | 0 |
| 35142956 | 2023 | Immortalization-upregulated protein promotes pancreatic cancer progression by regulating NPM1/FHL1-mediated cell-cycle-checkpoint protein activity. | 2 |
| 36695131 | 2023 | FHL1 as a novel prognostic biomarker and correlation with immune infiltration levels in lung adenocarcinoma. | 1 |
| 36864287 | 2023 | Identification of novel FHL1 mutations associated with X-linked scapuloperoneal myopathy in unrelated Chinese patients. | 0 |
| 36881973 | 2023 | Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells. | 0 |
| 35249471 | 2022 | Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation. | 4 |
| 35607917 | 2022 | Three novel FHL1 variants cause a mild phenotype of Emery-Dreifuss muscular dystrophy. | 1 |
| 35916339 | 2022 | Targeting FHL1 impairs cell proliferation and differentiation of acute myeloid leukemia cells. | 0 |
| 36017148 | 2022 | MiR-96-5p Facilitates Lung Adenocarcinoma Cell Phenotypes by Inhibiting FHL1. | 2 |
| 35249471 | 2022 | Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation. | 4 |
Citation
Dessen P
FHL1 (four and a half LIM domains 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45582/fhl1
