FIBCD1 (fibrinogen C domain containing 1)

2019-05-01  

Identity

HGNC
FIBCD1
LOCATION
9q34.12
LOCUSID
84929
ALIAS
-

Other Information

Locus ID:

NCBI: 84929
MIM: 613357
HGNC: 25922
Ensembl: ENSG00000130720

Variants:

dbSNP: 84929
ClinVar: 84929
TCGA: ENSG00000130720
COSMIC: FIBCD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130720ENST00000372337A3KFJ8
ENSG00000130720ENST00000372338Q8N539
ENSG00000130720ENST00000444139H0Y4Y8
ENSG00000130720ENST00000448616Q8N539
ENSG00000130720ENST00000451466X6RDH7

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
197104732009Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin.30
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
198927012010The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition.13
242933682014Crystal structure of the tetrameric fibrinogen-like recognition domain of fibrinogen C domain containing 1 (FIBCD1) protein.10
302796872018FIBCD1 Binds Aspergillus fumigatus and Regulates Lung Epithelial Response to Cell Wall Components.4
292206322018Immunohistochemical Localization of Fibrinogen C Domain Containing 1 on Epithelial and Mucosal Surfaces in Human Tissues.3
296596692018Overexpression of FIBCD1 Is Predictive of Poor Prognosis in Gastric Cancer.2

Citation

Dessen P

FIBCD1 (fibrinogen C domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-05-01

Online version: http://atlasgeneticsoncology.org/gene/57977/fibcd1