Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FIGLA (folliculogenesis specific bHLH transcription factor)

Identity

Alias_namesfolliculogenesis specific basic helix-loop-helix
Alias_symbol (synonym)bHLHc8
Other aliasBHLHC8
FIGALPHA
POF6
HGNC (Hugo) FIGLA
LocusID (NCBI) 344018
Atlas_Id 63384
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 70777310 and ends at 70790643 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FIGLA   24669
Cards
Entrez_Gene (NCBI)FIGLA  344018  folliculogenesis specific bHLH transcription factor
AliasesBHLHC8; FIGALPHA; POF6
GeneCards (Weizmann)FIGLA
Ensembl hg19 (Hinxton)ENSG00000183733 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183733 [Gene_View]  chr2:70777310-70790643 [Contig_View]  FIGLA [Vega]
ICGC DataPortalENSG00000183733
TCGA cBioPortalFIGLA
AceView (NCBI)FIGLA
Genatlas (Paris)FIGLA
WikiGenes344018
SOURCE (Princeton)FIGLA
Genetics Home Reference (NIH)FIGLA
Genomic and cartography
GoldenPath hg38 (UCSC)FIGLA  -     chr2:70777310-70790643 -  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FIGLA  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblFIGLA - 2p13.3 [CytoView hg19]  FIGLA - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIFIGLA [Mapview hg19]  FIGLA [Mapview hg38]
OMIM608697   612310   
Gene and transcription
Genbank (Entrez)AY541030 BC039536 BC146287 BC148798
RefSeq transcript (Entrez)NM_001004311
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FIGLA
Cluster EST : UnigeneHs.407636 [ NCBI ]
CGAP (NCI)Hs.407636
Alternative Splicing GalleryENSG00000183733
Gene ExpressionFIGLA [ NCBI-GEO ]   FIGLA [ EBI - ARRAY_EXPRESS ]   FIGLA [ SEEK ]   FIGLA [ MEM ]
Gene Expression Viewer (FireBrowse)FIGLA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344018
GTEX Portal (Tissue expression)FIGLA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6QHK4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6QHK4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6QHK4
Splice isoforms : SwissVarQ6QHK4
PhosPhoSitePlusQ6QHK4
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)FIGLA
DMDM Disease mutations344018
Blocks (Seattle)FIGLA
SuperfamilyQ6QHK4
Human Protein AtlasENSG00000183733
Peptide AtlasQ6QHK4
HPRD12279
IPIIPI00418236   
Protein Interaction databases
DIP (DOE-UCLA)Q6QHK4
IntAct (EBI)Q6QHK4
FunCoupENSG00000183733
BioGRIDFIGLA
STRING (EMBL)FIGLA
ZODIACFIGLA
Ontologies - Pathways
QuickGOQ6QHK4
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  nucleus  transcription factor complex  transcription from RNA polymerase II promoter  multicellular organism development  transcription factor binding  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  oocyte development  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  nucleus  transcription factor complex  transcription from RNA polymerase II promoter  multicellular organism development  transcription factor binding  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  oocyte development  
NDEx NetworkFIGLA
Atlas of Cancer Signalling NetworkFIGLA
Wikipedia pathwaysFIGLA
Orthology - Evolution
OrthoDB344018
GeneTree (enSembl)ENSG00000183733
Phylogenetic Trees/Animal Genes : TreeFamFIGLA
HOVERGENQ6QHK4
HOGENOMQ6QHK4
Homologs : HomoloGeneFIGLA
Homology/Alignments : Family Browser (UCSC)FIGLA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFIGLA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FIGLA
dbVarFIGLA
ClinVarFIGLA
1000_GenomesFIGLA 
Exome Variant ServerFIGLA
ExAC (Exome Aggregation Consortium)FIGLA (select the gene name)
Genetic variants : HAPMAP344018
Genomic Variants (DGV)FIGLA [DGVbeta]
DECIPHERFIGLA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFIGLA 
Mutations
ICGC Data PortalFIGLA 
TCGA Data PortalFIGLA 
Broad Tumor PortalFIGLA
OASIS PortalFIGLA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFIGLA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFIGLA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FIGLA
DgiDB (Drug Gene Interaction Database)FIGLA
DoCM (Curated mutations)FIGLA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FIGLA (select a term)
intoGenFIGLA
Cancer3DFIGLA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608697    612310   
Orphanet
MedgenFIGLA
Genetic Testing Registry FIGLA
NextProtQ6QHK4 [Medical]
TSGene344018
GENETestsFIGLA
Target ValidationFIGLA
Huge Navigator FIGLA [HugePedia]
snp3D : Map Gene to Disease344018
BioCentury BCIQFIGLA
ClinGenFIGLA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD344018
Chemical/Pharm GKB GenePA145008379
Clinical trialFIGLA
Miscellaneous
canSAR (ICR)FIGLA (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFIGLA
EVEXFIGLA
GoPubMedFIGLA
iHOPFIGLA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:08:30 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.