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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

Donate (in Euros)

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FKBP10 (FK506 binding protein 10, 65 kDa)


Other namesBRKS1
HGNC (Hugo) FKBP10
LocusID (NCBI) 60681
Location 17q21.2
Location_base_pair Starts at 39968962 and ends at 39979469 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

HGNC (Hugo)FKBP10   18169
Entrez_Gene (NCBI)FKBP10  60681  FK506 binding protein 10, 65 kDa
GeneCards (Weizmann)FKBP10
Ensembl hg19 (Hinxton)ENSG00000141756 [Gene_View]  chr17:39968962-39979469 [Contig_View]  FKBP10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000141756 [Gene_View]  chr17:39968962-39979469 [Contig_View]  FKBP10 [Vega]
ICGC DataPortalENSG00000141756
AceView (NCBI)FKBP10
Genatlas (Paris)FKBP10
SOURCE (Princeton)FKBP10
Genomic and cartography
GoldenPath hg19 (UCSC)FKBP10  -     chr17:39968962-39979469 +  17q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FKBP10  -     17q21.2   [Description]    (hg38-Dec_2013)
EnsemblFKBP10 - 17q21.2 [CytoView hg19]  FKBP10 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIFKBP10 [Mapview hg19]  FKBP10 [Mapview hg38]
OMIM259450   607063   610968   
Gene and transcription
Genbank (Entrez)AB045981 AF337909 AI095261 AK000690 AK025694
RefSeq transcript (Entrez)NM_021939
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_015860 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)FKBP10
Cluster EST : UnigeneHs.463035 [ NCBI ]
CGAP (NCI)Hs.463035
Alternative Splicing : Fast-db (Paris)GSHG0012496
Alternative Splicing GalleryENSG00000141756
Gene ExpressionFKBP10 [ NCBI-GEO ]     FKBP10 [ SEEK ]   FKBP10 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AY3 (Uniprot)
NextProtQ96AY3  [Medical]
With graphics : InterProQ96AY3
Splice isoforms : SwissVarQ96AY3 (Swissvar)
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ] [ IntEnz-EBI ] [ BRENDA ] [ KEGG ]   
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    ER_TARGET (PS00014)    FKBP_PPIASE (PS50059)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    PPIase_FKBP    PPIase_FKBP_dom   
Related proteins : CluSTrQ96AY3
Domain families : Pfam (Sanger)EF-hand_5 (PF13202)    FKBP_C (PF00254)   
Domain families : Pfam (NCBI)pfam13202    pfam00254   
Domain families : Smart (EMBL)EFh (SM00054)  
DMDM Disease mutations60681
Blocks (Seattle)Q96AY3
Human Protein AtlasENSG00000141756
Peptide AtlasQ96AY3
IPIIPI00303300   IPI00909121   IPI01013799   IPI00184854   IPI00334818   
Protein Interaction databases
IntAct (EBI)Q96AY3
Ontologies - Pathways
Ontology : AmiGOprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Protein Interaction DatabaseFKBP10
DoCM (Curated mutations)FKBP10
Wikipedia pathwaysFKBP10
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerFKBP10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FKBP10
Exome Variant ServerFKBP10
SNP (GeneSNP Utah)FKBP10
Genetic variants : HAPMAPFKBP10
Genomic Variants (DGV)FKBP10 [DGVbeta]
ICGC Data PortalENSG00000141756 
Somatic Mutations in Cancer : COSMICFKBP10 
CONAN: Copy Number AnalysisFKBP10 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Osteogenesis Imperfecta Variant Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)17:39968962-39979469
Mutations and Diseases : HGMDFKBP10
OMIM259450    607063    610968   
NextProtQ96AY3 [Medical]
Disease Genetic AssociationFKBP10
Huge Navigator FKBP10 [HugePedia]  FKBP10 [HugeCancerGEM]
snp3D : Map Gene to Disease60681
DGIdb (Drug Gene Interaction db)FKBP10
General knowledge
Homologs : HomoloGeneFKBP10
Homology/Alignments : Family Browser (UCSC)FKBP10
Phylogenetic Trees/Animal Genes : TreeFamFKBP10
Chemical/Protein Interactions : CTD60681
Chemical/Pharm GKB GenePA28152
Clinical trialFKBP10
Cancer Resource (Charite)ENSG00000141756
Other databases
PubMed28 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:24:35 CET 2015

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