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FKBP10 (FK506 binding protein 10, 65 kDa)

Identity

Other namesBRKS1
FKBP65
OI11
OI6
PPIASE
hFKBP65
HGNC (Hugo) FKBP10
LocusID (NCBI) 60681
Atlas_Id 52417
Location 17q21.2
Location_base_pair Starts at 39968962 and ends at 39979469 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FKBP10   18169
Cards
Entrez_Gene (NCBI)FKBP10  60681  FK506 binding protein 10, 65 kDa
GeneCards (Weizmann)FKBP10
Ensembl hg19 (Hinxton)ENSG00000141756 [Gene_View]  chr17:39968962-39979469 [Contig_View]  FKBP10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000141756 [Gene_View]  chr17:39968962-39979469 [Contig_View]  FKBP10 [Vega]
ICGC DataPortalENSG00000141756
TCGA cBioPortalFKBP10
AceView (NCBI)FKBP10
Genatlas (Paris)FKBP10
WikiGenes60681
SOURCE (Princeton)FKBP10
Genomic and cartography
GoldenPath hg19 (UCSC)FKBP10  -     chr17:39968962-39979469 +  17q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FKBP10  -     17q21.2   [Description]    (hg38-Dec_2013)
EnsemblFKBP10 - 17q21.2 [CytoView hg19]  FKBP10 - 17q21.2 [CytoView hg38]
Mapping of homologs : NCBIFKBP10 [Mapview hg19]  FKBP10 [Mapview hg38]
OMIM259450   607063   610968   
Gene and transcription
Genbank (Entrez)AB045981 AF337909 AI095261 AK000690 AK025694
RefSeq transcript (Entrez)NM_021939
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_015860 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)FKBP10
Cluster EST : UnigeneHs.463035 [ NCBI ]
CGAP (NCI)Hs.463035
Alternative Splicing : Fast-db (Paris)GSHG0012496
Alternative Splicing GalleryENSG00000141756
Gene ExpressionFKBP10 [ NCBI-GEO ]     FKBP10 [ SEEK ]   FKBP10 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AY3 (Uniprot)
NextProtQ96AY3  [Medical]  [Publications]
With graphics : InterProQ96AY3
Splice isoforms : SwissVarQ96AY3 (Swissvar)
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    ER_TARGET (PS00014)    FKBP_PPIASE (PS50059)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    PPIase_FKBP    PPIase_FKBP_dom   
Related proteins : CluSTrQ96AY3
Domain families : Pfam (Sanger)EF-hand_5 (PF13202)    FKBP_C (PF00254)   
Domain families : Pfam (NCBI)pfam13202    pfam00254   
Domain families : Smart (EMBL)EFh (SM00054)  
DMDM Disease mutations60681
Blocks (Seattle)Q96AY3
Human Protein AtlasENSG00000141756
Peptide AtlasQ96AY3
HPRD09522
IPIIPI00303300   IPI00909121   IPI01013799   IPI00184854   IPI00334818   
Protein Interaction databases
DIP (DOE-UCLA)Q96AY3
IntAct (EBI)Q96AY3
FunCoupENSG00000141756
BioGRIDFKBP10
IntegromeDBFKBP10
STRING (EMBL)FKBP10
Ontologies - Pathways
QuickGOQ96AY3
Ontology : AmiGOprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  cytoplasm  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  cytoplasm  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Protein Interaction DatabaseFKBP10
DoCM (Curated mutations)FKBP10
Wikipedia pathwaysFKBP10
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerFKBP10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FKBP10
dbVarFKBP10
ClinVarFKBP10
1000_GenomesFKBP10 
Exome Variant ServerFKBP10
SNP (GeneSNP Utah)FKBP10
SNP : HGBaseFKBP10
Genetic variants : HAPMAPFKBP10
Genomic Variants (DGV)FKBP10 [DGVbeta]
Mutations
ICGC Data PortalFKBP10 
TCGA Data PortalFKBP10 
Tumor PortalFKBP10
Somatic Mutations in Cancer : COSMICFKBP10 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Osteogenesis Imperfecta Variant Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:39968962-39979469
CONAN: Copy Number AnalysisFKBP10 
Mutations and Diseases : HGMDFKBP10
OMIM259450    607063    610968   
MedgenFKBP10
NextProtQ96AY3 [Medical]
GENETestsFKBP10
Disease Genetic AssociationFKBP10
Huge Navigator FKBP10 [HugePedia]  FKBP10 [HugeCancerGEM]
snp3D : Map Gene to Disease60681
DGIdb (Drug Gene Interaction db)FKBP10
BioCentury BCIQFKBP10
General knowledge
Homologs : HomoloGeneFKBP10
Homology/Alignments : Family Browser (UCSC)FKBP10
Phylogenetic Trees/Animal Genes : TreeFamFKBP10
Chemical/Protein Interactions : CTD60681
Chemical/Pharm GKB GenePA28152
Clinical trialFKBP10
Cancer Resource (Charite)ENSG00000141756
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
CoreMineFKBP10
GoPubMedFKBP10
iHOPFKBP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 11:34:15 CEST 2015

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