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FKBP10 (FK506 binding protein 10, 65 kDa)

Identity

Other namesFKBP65
OI11
OI6
PPIASE
hFKBP65
HGNC (Hugo) FKBP10
LocusID (NCBI) 60681
Location 17q21.2
Location_base_pair Starts at 39968962 and ends at 39979469 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)FKBP10   18169
Cards
Entrez_Gene (NCBI)FKBP10  60681  FK506 binding protein 10, 65 kDa
GeneCards (Weizmann)FKBP10
Ensembl (Hinxton)ENSG00000141756 [Gene_View]  chr17:39968962-39979469 [Contig_View]  FKBP10 [Vega]
ICGC DataPortalENSG00000141756
cBioPortalFKBP10
AceView (NCBI)FKBP10
Genatlas (Paris)FKBP10
WikiGenes60681
SOURCE (Princeton)NM_021939
Genomic and cartography
GoldenPath (UCSC)FKBP10  -  17q21.2   chr17:39968962-39979469 +  17q21.2   [Description]    (hg19-Feb_2009)
EnsemblFKBP10 - 17q21.2 [CytoView]
Mapping of homologs : NCBIFKBP10 [Mapview]
OMIM607063   610968   
Gene and transcription
Genbank (Entrez)AB045981 AF337909 AI095261 AK000690 AK025694
RefSeq transcript (Entrez)NM_021939
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_015860 NT_010783 NW_001838436 NW_004929407
Consensus coding sequences : CCDS (NCBI)FKBP10
Cluster EST : UnigeneHs.463035 [ NCBI ]
CGAP (NCI)Hs.463035
Alternative Splicing : Fast-db (Paris)GSHG0012496
Alternative Splicing GalleryENSG00000141756
Gene ExpressionFKBP10 [ NCBI-GEO ]     FKBP10 [ SEEK ]   FKBP10 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AY3 (Uniprot)
NextProtQ96AY3  [Medical]
With graphics : InterProQ96AY3
Splice isoforms : SwissVarQ96AY3 (Swissvar)
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    ER_TARGET (PS00014)    FKBP_PPIASE (PS50059)   
Domains : Interpro (EBI)EF-hand-dom_pair [organisation]   EF_Hand_1_Ca_BS [organisation]   EF_hand_dom [organisation]   PPIase_FKBP [organisation]   PPIase_FKBP_dom [organisation]  
Related proteins : CluSTrQ96AY3
Domain families : Pfam (Sanger)EF-hand_5 (PF13202)    FKBP_C (PF00254)   
Domain families : Pfam (NCBI)pfam13202    pfam00254   
Domain families : Smart (EMBL)EFh (SM00054)  
DMDM Disease mutations60681
Blocks (Seattle)Q96AY3
Human Protein AtlasENSG00000141756 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ96AY3
HPRD09522
IPIIPI00303300   IPI00909121   IPI01013799   IPI00184854   IPI00334818   
Protein Interaction databases
DIP (DOE-UCLA)Q96AY3
IntAct (EBI)Q96AY3
FunCoupENSG00000141756
BioGRIDFKBP10
InParanoidQ96AY3
Interologous Interaction database Q96AY3
IntegromeDBFKBP10
STRING (EMBL)FKBP10
Ontologies - Pathways
Ontology : AmiGOprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  calcium ion binding  FK506 binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  chaperone-mediated protein folding  
Protein Interaction DatabaseFKBP10
Wikipedia pathwaysFKBP10
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FKBP10
snp3D : Map Gene to Disease60681
SNP (GeneSNP Utah)FKBP10
SNP : HGBaseFKBP10
Genetic variants : HAPMAPFKBP10
Exome VariantFKBP10
1000_GenomesFKBP10 
ICGC programENSG00000141756 
Somatic Mutations in Cancer : COSMICFKBP10 
CONAN: Copy Number AnalysisFKBP10 
Mutations and Diseases : HGMDFKBP10
Mutations and Diseases : intOGenFKBP10
Genomic VariantsFKBP10  FKBP10 [DGVbeta]
dbVarFKBP10
ClinVarFKBP10
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM607063    610968   
MedgenFKBP10
GENETestsFKBP10
Disease Genetic AssociationFKBP10
Huge Navigator FKBP10 [HugePedia]  FKBP10 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneFKBP10
Homology/Alignments : Family Browser (UCSC)FKBP10
Phylogenetic Trees/Animal Genes : TreeFamFKBP10
Chemical/Protein Interactions : CTD60681
Chemical/Pharm GKB GenePA28152
Clinical trialFKBP10
Cancer Resource (Charite)ENSG00000141756
Other databases
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
CoreMineFKBP10
iHOPFKBP10
OncoSearchFKBP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:47:01 CEST 2014

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