FKBP1A (FK506 binding protein 1A, 12kDa)

Identity

Other names	FKBP-12
	FKBP1
	FKBP12
	FKBP12C
	PKC12
	PKCI2
	PPIASE
HGNC	FKBP1A
Location	20p13
Location_base_pair	Starts at 1297622 and ends at 1321745 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

External links

	Nomenclature
HGNC	FKBP1A   3711
Entrez_Gene	FKBP1A  2280  FK506 binding protein 1A, 12kDa
	Cards
GeneCards	FKBP1A
Ensembl	FKBP1A [Search_View]   ENSG00000088832 [Gene_View]
Genatlas	FKBP1A
GeneLynx	FKBP1A
eGenome	FKBP1A
euGene	2280
	Genomic and cartography
GoldenPath	FKBP1A  -  20p13   chr20:1297622-1321745 -  20p13   [Description]    (hg18-March_2006)
Ensembl	FKBP1A - 20p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	FKBP1A
	Gene and transcription
Genbank	AB241123 [ ENTREZ ]
Genbank	AB241125 [ ENTREZ ]
Genbank	AF205192 [ ENTREZ ]
Genbank	BC001925 [ ENTREZ ]
Genbank	BC005147 [ ENTREZ ]
RefSeq	NM_000801 [ SRS ]    NM_000801 [ ENTREZ ]
RefSeq	NM_054014 [ SRS ]    NM_054014 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
AceView	FKBP1A AceView - NCBI
Unigene	Hs.700839 [ SRS ]    Hs.700839 [ NCBI ]     HS700839 [ spliceNest ]
	Protein : pattern, domain, 3D structure
SwissProt	P62942 [ SRS]    P62942 [ EXPASY ]     P62942 [ INTERPRO ]     P62942 [ UNIPROT ]
Prosite	PS50059 FKBP_PPIASE [ SRS ]    PS50059 FKBP_PPIASE [ Expasy ]
Interpro	IPR001179 PPIase_FKBP [ SRS ]    IPR001179 PPIase_FKBP [ EBI ]
CluSTr	P62942
Pfam	PF00254 FKBP_C [ SRS ]    PF00254 FKBP_C [ Sanger ]    pfam00254 [ NCBI-CDD ]
Blocks	P62942
PDB	1A7X [ SRS ]    1A7X [ PdbSum ],   1A7X [ IMB ]   1A7X [ RSDB ]
PDB	1B6C [ SRS ]    1B6C [ PdbSum ],   1B6C [ IMB ]   1B6C [ RSDB ]
PDB	1BKF [ SRS ]    1BKF [ PdbSum ],   1BKF [ IMB ]   1BKF [ RSDB ]
PDB	1BL4 [ SRS ]    1BL4 [ PdbSum ],   1BL4 [ IMB ]   1BL4 [ RSDB ]
PDB	1D6O [ SRS ]    1D6O [ PdbSum ],   1D6O [ IMB ]   1D6O [ RSDB ]
PDB	1D7H [ SRS ]    1D7H [ PdbSum ],   1D7H [ IMB ]   1D7H [ RSDB ]
PDB	1D7I [ SRS ]    1D7I [ PdbSum ],   1D7I [ IMB ]   1D7I [ RSDB ]
PDB	1D7J [ SRS ]    1D7J [ PdbSum ],   1D7J [ IMB ]   1D7J [ RSDB ]
PDB	1EYM [ SRS ]    1EYM [ PdbSum ],   1EYM [ IMB ]   1EYM [ RSDB ]
PDB	1F40 [ SRS ]    1F40 [ PdbSum ],   1F40 [ IMB ]   1F40 [ RSDB ]
PDB	1FAP [ SRS ]    1FAP [ PdbSum ],   1FAP [ IMB ]   1FAP [ RSDB ]
PDB	1FKB [ SRS ]    1FKB [ PdbSum ],   1FKB [ IMB ]   1FKB [ RSDB ]
PDB	1FKD [ SRS ]    1FKD [ PdbSum ],   1FKD [ IMB ]   1FKD [ RSDB ]
PDB	1FKF [ SRS ]    1FKF [ PdbSum ],   1FKF [ IMB ]   1FKF [ RSDB ]
PDB	1FKG [ SRS ]    1FKG [ PdbSum ],   1FKG [ IMB ]   1FKG [ RSDB ]
PDB	1FKH [ SRS ]    1FKH [ PdbSum ],   1FKH [ IMB ]   1FKH [ RSDB ]
PDB	1FKI [ SRS ]    1FKI [ PdbSum ],   1FKI [ IMB ]   1FKI [ RSDB ]
PDB	1FKJ [ SRS ]    1FKJ [ PdbSum ],   1FKJ [ IMB ]   1FKJ [ RSDB ]
PDB	1FKR [ SRS ]    1FKR [ PdbSum ],   1FKR [ IMB ]   1FKR [ RSDB ]
PDB	1FKS [ SRS ]    1FKS [ PdbSum ],   1FKS [ IMB ]   1FKS [ RSDB ]
PDB	1FKT [ SRS ]    1FKT [ PdbSum ],   1FKT [ IMB ]   1FKT [ RSDB ]
PDB	1J4H [ SRS ]    1J4H [ PdbSum ],   1J4H [ IMB ]   1J4H [ RSDB ]
PDB	1J4I [ SRS ]    1J4I [ PdbSum ],   1J4I [ IMB ]   1J4I [ RSDB ]
PDB	1J4R [ SRS ]    1J4R [ PdbSum ],   1J4R [ IMB ]   1J4R [ RSDB ]
PDB	1NSG [ SRS ]    1NSG [ PdbSum ],   1NSG [ IMB ]   1NSG [ RSDB ]
PDB	1QPF [ SRS ]    1QPF [ PdbSum ],   1QPF [ IMB ]   1QPF [ RSDB ]
PDB	1QPL [ SRS ]    1QPL [ PdbSum ],   1QPL [ IMB ]   1QPL [ RSDB ]
PDB	1TCO [ SRS ]    1TCO [ PdbSum ],   1TCO [ IMB ]   1TCO [ RSDB ]
PDB	2DG3 [ SRS ]    2DG3 [ PdbSum ],   2DG3 [ IMB ]   2DG3 [ RSDB ]
PDB	2DG4 [ SRS ]    2DG4 [ PdbSum ],   2DG4 [ IMB ]   2DG4 [ RSDB ]
PDB	2DG9 [ SRS ]    2DG9 [ PdbSum ],   2DG9 [ IMB ]   2DG9 [ RSDB ]
PDB	2FAP [ SRS ]    2FAP [ PdbSum ],   2FAP [ IMB ]   2FAP [ RSDB ]
PDB	2FKE [ SRS ]    2FKE [ PdbSum ],   2FKE [ IMB ]   2FKE [ RSDB ]
PDB	3FAP [ SRS ]    3FAP [ PdbSum ],   3FAP [ IMB ]   3FAP [ RSDB ]
PDB	4FAP [ SRS ]    4FAP [ PdbSum ],   4FAP [ IMB ]   4FAP [ RSDB ]
HPRD	01741
	Protein Interaction databases
DIP	P62942
IntAct	P62942
	Polymorphism : SNP, mutations, diseases
OMIM	186945    [ map ]
GENECLINICS	186945
SNP	FKBP1A [dbSNP-NCBI]
SNP	NM_000801 [SNP-NCI]
SNP	NM_054014 [SNP-NCI]
SNP	FKBP1A [GeneSNPs - Utah]  FKBP1A] [HGBASE - SRS]
HAPMAP	FKBP1A [HAPMAP]
COSMIC	FKBP1A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	FKBP1A
	General knowledge
Family Browser	FKBP1A [UCSC Family Browser]
SOURCE	NM_000801
SOURCE	NM_054014
SMD	Hs.700839
SAGE	Hs.700839
Enzyme	5.2.1.8 [ Enzyme-Expasy ]   5.2.1.8 [ Enzyme-SRS ]   5.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   5.2.1.8 [ WIT ]
GO	peptidyl-prolyl cis-trans isomerase activity [Amigo]  peptidyl-prolyl cis-trans isomerase activity
GO	receptor activity [Amigo]  receptor activity
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein folding [Amigo]  protein folding
GO	protein folding [Amigo]  protein folding
GO	isomerase activity [Amigo]  isomerase activity
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
BIOCARTA	mTOR Signaling Pathway    [Genes]
BIOCARTA	NFAT and Hypertrophy of the heart (Transcription in the broken heart)    [Genes]
PubGene	FKBP1A
TreeFam	FKBP1A
CTD	2280 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FKBP1A Related clones (RZPD - Berlin)
	PubMed
PubMed	72 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:41:40 2008