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FKBP3 (FK506 binding protein 3)

Identity

Alias_namesFK506-binding protein 3 (25kD)
FK506 binding protein 3, 25kDa
Alias_symbol (synonym)FKBP-25
PPIase
Other aliasFKBP-3
FKBP25
HGNC (Hugo) FKBP3
LocusID (NCBI) 2287
Atlas_Id 63398
Location 14q21.2  [Link to chromosome band 14q21]
Location_base_pair Starts at 45115599 and ends at 45134529 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DTD1 (20p11.23) / FKBP3 (14q21.2)FKBP3 (14q21.2) / COX5A (15q24.2)FKBP3 (14q21.2) / FKBP3 (14q21.2)
FKBP3 (14q21.2) / PIP5K1C (19p13.3)FKBP3 (14q21.2) / RGS5 (1q23.3)GALNT11 (7q36.1) / FKBP3 (14q21.2)
NAA60 (16p13.3) / FKBP3 (14q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FKBP3   3719
Cards
Entrez_Gene (NCBI)FKBP3  2287  FK506 binding protein 3
AliasesFKBP-25; FKBP-3; FKBP25; PPIase
GeneCards (Weizmann)FKBP3
Ensembl hg19 (Hinxton)ENSG00000100442 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100442 [Gene_View]  chr14:45115599-45134529 [Contig_View]  FKBP3 [Vega]
ICGC DataPortalENSG00000100442
TCGA cBioPortalFKBP3
AceView (NCBI)FKBP3
Genatlas (Paris)FKBP3
WikiGenes2287
SOURCE (Princeton)FKBP3
Genetics Home Reference (NIH)FKBP3
Genomic and cartography
GoldenPath hg38 (UCSC)FKBP3  -     chr14:45115599-45134529 -  14q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FKBP3  -     14q21.2   [Description]    (hg19-Feb_2009)
EnsemblFKBP3 - 14q21.2 [CytoView hg19]  FKBP3 - 14q21.2 [CytoView hg38]
Mapping of homologs : NCBIFKBP3 [Mapview hg19]  FKBP3 [Mapview hg38]
OMIM186947   
Gene and transcription
Genbank (Entrez)AK222993 AK311915 BC016288 BC020809 BI598048
RefSeq transcript (Entrez)NM_002013
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FKBP3
Cluster EST : UnigeneHs.509226 [ NCBI ]
CGAP (NCI)Hs.509226
Alternative Splicing GalleryENSG00000100442
Gene ExpressionFKBP3 [ NCBI-GEO ]   FKBP3 [ EBI - ARRAY_EXPRESS ]   FKBP3 [ SEEK ]   FKBP3 [ MEM ]
Gene Expression Viewer (FireBrowse)FKBP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2287
GTEX Portal (Tissue expression)FKBP3
Human Protein AtlasENSG00000100442-FKBP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ00688   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00688  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00688
Splice isoforms : SwissVarQ00688
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
PhosPhoSitePlusQ00688
Domaine pattern : Prosite (Expaxy)FKBP_PPIASE (PS50059)   
Domains : Interpro (EBI)PPIase_FKBP    PPIase_FKBP_dom   
Domain families : Pfam (Sanger)FKBP_C (PF00254)   
Domain families : Pfam (NCBI)pfam00254   
Conserved Domain (NCBI)FKBP3
DMDM Disease mutations2287
Blocks (Seattle)FKBP3
PDB (SRS)1PBK    2KFV    2MPH    5D75    5GPG   
PDB (PDBSum)1PBK    2KFV    2MPH    5D75    5GPG   
PDB (IMB)1PBK    2KFV    2MPH    5D75    5GPG   
PDB (RSDB)1PBK    2KFV    2MPH    5D75    5GPG   
Structural Biology KnowledgeBase1PBK    2KFV    2MPH    5D75    5GPG   
SCOP (Structural Classification of Proteins)1PBK    2KFV    2MPH    5D75    5GPG   
CATH (Classification of proteins structures)1PBK    2KFV    2MPH    5D75    5GPG   
SuperfamilyQ00688
Human Protein Atlas [tissue]ENSG00000100442-FKBP3 [tissue]
Peptide AtlasQ00688
HPRD01743
IPIIPI00024157   IPI01026077   
Protein Interaction databases
DIP (DOE-UCLA)Q00688
IntAct (EBI)Q00688
FunCoupENSG00000100442
BioGRIDFKBP3
STRING (EMBL)FKBP3
ZODIACFKBP3
Ontologies - Pathways
QuickGOQ00688
Ontology : AmiGOprotein peptidyl-prolyl isomerization  RNA binding  peptidyl-prolyl cis-trans isomerase activity  receptor activity  protein binding  FK506 binding  nucleus  cytoplasm  chaperone-mediated protein folding  
Ontology : EGO-EBIprotein peptidyl-prolyl isomerization  RNA binding  peptidyl-prolyl cis-trans isomerase activity  receptor activity  protein binding  FK506 binding  nucleus  cytoplasm  chaperone-mediated protein folding  
NDEx NetworkFKBP3
Atlas of Cancer Signalling NetworkFKBP3
Wikipedia pathwaysFKBP3
Orthology - Evolution
OrthoDB2287
GeneTree (enSembl)ENSG00000100442
Phylogenetic Trees/Animal Genes : TreeFamFKBP3
HOVERGENQ00688
HOGENOMQ00688
Homologs : HomoloGeneFKBP3
Homology/Alignments : Family Browser (UCSC)FKBP3
Gene fusions - Rearrangements
Tumor Fusion PortalFKBP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFKBP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FKBP3
dbVarFKBP3
ClinVarFKBP3
1000_GenomesFKBP3 
Exome Variant ServerFKBP3
ExAC (Exome Aggregation Consortium)ENSG00000100442
GNOMAD BrowserENSG00000100442
Genetic variants : HAPMAP2287
Genomic Variants (DGV)FKBP3 [DGVbeta]
DECIPHERFKBP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFKBP3 
Mutations
ICGC Data PortalFKBP3 
TCGA Data PortalFKBP3 
Broad Tumor PortalFKBP3
OASIS PortalFKBP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFKBP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFKBP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FKBP3
DgiDB (Drug Gene Interaction Database)FKBP3
DoCM (Curated mutations)FKBP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FKBP3 (select a term)
intoGenFKBP3
Cancer3DFKBP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM186947   
Orphanet
DisGeNETFKBP3
MedgenFKBP3
Genetic Testing Registry FKBP3
NextProtQ00688 [Medical]
TSGene2287
GENETestsFKBP3
Target ValidationFKBP3
Huge Navigator FKBP3 [HugePedia]
snp3D : Map Gene to Disease2287
BioCentury BCIQFKBP3
ClinGenFKBP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2287
Chemical/Pharm GKB GenePA28160
Clinical trialFKBP3
Miscellaneous
canSAR (ICR)FKBP3 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFKBP3
EVEXFKBP3
GoPubMedFKBP3
iHOPFKBP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:29:28 CET 2017

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