FKBP4 (FK506 binding protein 4, 59kDa)

Identity

Other names	FKBP52
	FKBP59
	HBI
	Hsp56
	PPIase
	p52
HGNC	FKBP4
Location	12p13.33
Location_base_pair	Starts at 2774414 and ends at 2783385 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	FKBP4   3720
Entrez_Gene	FKBP4  2288  FK506 binding protein 4, 59kDa
	Cards
GeneCards	FKBP4
Ensembl	FKBP4 [Search_View]   ENSG00000004478 [Gene_View]
Genatlas	FKBP4
GeneLynx	FKBP4
eGenome	FKBP4
euGene	2288
	Genomic and cartography
GoldenPath	FKBP4  -  12p13.33   chr12:2774414-2783385 +  12p13.33   [Description]    (hg18-March_2006)
Ensembl	FKBP4 - 12p13.33 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	FKBP4
	Gene and transcription
Genbank	AK024694 [ ENTREZ ]
Genbank	AK313918 [ ENTREZ ]
Genbank	BC001786 [ ENTREZ ]
Genbank	BC002887 [ ENTREZ ]
Genbank	BC007924 [ ENTREZ ]
RefSeq	NM_002014 [ SRS ]    NM_002014 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	AC_000144 [ SRS ]    AC_000144 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NT_009759 [ SRS ]    NT_009759 [ ENTREZ ]
RefSeq	NW_001838049 [ SRS ]    NW_001838049 [ ENTREZ ]
RefSeq	NW_925295 [ SRS ]    NW_925295 [ ENTREZ ]
AceView	FKBP4 AceView - NCBI
Unigene	Hs.598828 [ SRS ]    Hs.598828 [ NCBI ]     HS598828 [ spliceNest ]
Fast-db	488 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q02790 [ SRS]    Q02790 [ EXPASY ]     Q02790 [ INTERPRO ]     Q02790 [ UNIPROT ]
Prosite	PS50059 FKBP_PPIASE [ SRS ]    PS50059 FKBP_PPIASE [ Expasy ]
Prosite	PS50005 TPR [ SRS ]    PS50005 TPR [ Expasy ]
Prosite	PS50293 TPR_REGION [ SRS ]    PS50293 TPR_REGION [ Expasy ]
Interpro	IPR001179 PPIase_FKBP [ SRS ]    IPR001179 PPIase_FKBP [ EBI ]
Interpro	IPR001440 TPR-1 [ SRS ]    IPR001440 TPR-1 [ EBI ]
Interpro	IPR011990 TPR-like_helical [ SRS ]    IPR011990 TPR-like_helical [ EBI ]
Interpro	IPR013026 TPR_region [ SRS ]    IPR013026 TPR_region [ EBI ]
CluSTr	Q02790
Pfam	PF00254 FKBP_C [ SRS ]    PF00254 FKBP_C [ Sanger ]    pfam00254 [ NCBI-CDD ]
Pfam	PF00515 TPR_1 [ SRS ]    PF00515 TPR_1 [ Sanger ]    pfam00515 [ NCBI-CDD ]
Smart	SM00028 TPR [EMBL]
Blocks	Q02790
PDB	1N1A [ SRS ]    1N1A [ PdbSum ],   1N1A [ IMB ]   1N1A [ RSDB ]
PDB	1P5Q [ SRS ]    1P5Q [ PdbSum ],   1P5Q [ IMB ]   1P5Q [ RSDB ]
PDB	1Q1C [ SRS ]    1Q1C [ PdbSum ],   1Q1C [ IMB ]   1Q1C [ RSDB ]
PDB	1QZ2 [ SRS ]    1QZ2 [ PdbSum ],   1QZ2 [ IMB ]   1QZ2 [ RSDB ]
HPRD	11794
	Protein Interaction databases
DIP	Q02790
IntAct	Q02790
	Polymorphism : SNP, mutations, diseases
OMIM	600611    [ map ]
GENECLINICS	600611
SNP	FKBP4 [dbSNP-NCBI]
SNP	NM_002014 [SNP-NCI]
SNP	FKBP4 [GeneSNPs - Utah]  FKBP4] [HGBASE - SRS]
HAPMAP	FKBP4 [HAPMAP]
COSMIC	FKBP4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	FKBP4
	General knowledge
Family Browser	FKBP4 [UCSC Family Browser]
SOURCE	NM_002014
SMD	Hs.598828
SAGE	Hs.598828
Enzyme	5.2.1.8 [ Enzyme-Expasy ]   5.2.1.8 [ Enzyme-SRS ]   5.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   5.2.1.8 [ WIT ]
GO	peptidyl-prolyl cis-trans isomerase activity [Amigo]  peptidyl-prolyl cis-trans isomerase activity
GO	ATP binding [Amigo]  ATP binding
GO	GTP binding [Amigo]  GTP binding
GO	FK506 binding [Amigo]  FK506 binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	protein folding [Amigo]  protein folding
GO	steroid hormone receptor complex assembly [Amigo]  steroid hormone receptor complex assembly
GO	copper ion transport [Amigo]  copper ion transport
GO	embryo implantation [Amigo]  embryo implantation
GO	isomerase activity [Amigo]  isomerase activity
GO	protein binding, bridging [Amigo]  protein binding, bridging
GO	heat shock protein binding [Amigo]  heat shock protein binding
GO	protein complex localization [Amigo]  protein complex localization
GO	glucocorticoid receptor binding [Amigo]  glucocorticoid receptor binding
GO	male sex differentiation [Amigo]  male sex differentiation
GO	phosphoprotein binding [Amigo]  phosphoprotein binding
PubGene	FKBP4
TreeFam	FKBP4
CTD	2288 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FKBP4 Related clones (RZPD - Berlin)
	PubMed
PubMed	40 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:41:40 2008