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FLAD1 (flavin adenine dinucleotide synthetase 1)

Identity

Alias (NCBI)FAD1
FADS
LSMFLAD
PP591
HGNC (Hugo) FLAD1
HGNC Alias symbPP591
FAD1
HGNC Previous nameFad1, flavin adenine dinucleotide synthetase, homolog (yeast)
 FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae)
 flavin adenine dinucleotide synthetase
LocusID (NCBI) 80308
Atlas_Id 63408
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 154983344 and ends at 154993111 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EFNA3 (1q22) / FLAD1 (1q21.3)EFNA4 (1q22) / FLAD1 (1q21.3)FLAD1 (1q21.3) / EGR3 (8p21.3)
RP11-540D14.8 () / FLAD1 (1q21.3)RP11-540D14.8 FLAD1EFNA4 FLAD1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FLAD1   24671
Cards
Entrez_Gene (NCBI)FLAD1    flavin adenine dinucleotide synthetase 1
AliasesFAD1; FADS; LSMFLAD; PP591
GeneCards (Weizmann)FLAD1
Ensembl hg19 (Hinxton)ENSG00000160688 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160688 [Gene_View]  ENSG00000160688 [Sequence]  chr1:154983344-154993111 [Contig_View]  FLAD1 [Vega]
ICGC DataPortalENSG00000160688
TCGA cBioPortalFLAD1
AceView (NCBI)FLAD1
Genatlas (Paris)FLAD1
SOURCE (Princeton)FLAD1
Genetics Home Reference (NIH)FLAD1
Genomic and cartography
GoldenPath hg38 (UCSC)FLAD1  -     chr1:154983344-154993111 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FLAD1  -     1q21.3   [Description]    (hg19-Feb_2009)
GoldenPathFLAD1 - 1q21.3 [CytoView hg19]  FLAD1 - 1q21.3 [CytoView hg38]
ImmunoBaseENSG00000160688
Genome Data Viewer NCBIFLAD1 [Mapview hg19]  
OMIM255100   610595   
Gene and transcription
Genbank (Entrez)AF218022 AF481877 AF520568 AK025979 AK090542
RefSeq transcript (Entrez)NM_001184891 NM_001184892 NM_025207 NM_201398
Consensus coding sequences : CCDS (NCBI)FLAD1
Gene ExpressionFLAD1 [ NCBI-GEO ]   FLAD1 [ EBI - ARRAY_EXPRESS ]   FLAD1 [ SEEK ]   FLAD1 [ MEM ]
Gene Expression Viewer (FireBrowse)FLAD1 [ Firebrowse - Broad ]
GenevisibleExpression of FLAD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80308
GTEX Portal (Tissue expression)FLAD1
Human Protein AtlasENSG00000160688-FLAD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFF5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFF5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFF5
PhosPhoSitePlusQ8NFF5
Domains : Interpro (EBI)FAD_synth_MoaB/Mog-bd    MoaB/Mog-like_dom_sf    MoaB/Mog_dom    PAPS_reduct    Rossmann-like_a/b/a_fold   
Domain families : Pfam (Sanger)MoCF_biosynth (PF00994)    PAPS_reduct (PF01507)   
Domain families : Pfam (NCBI)pfam00994    pfam01507   
Domain families : Smart (EMBL)MoCF_biosynth (SM00852)  
Conserved Domain (NCBI)FLAD1
SuperfamilyQ8NFF5
AlphaFold pdb e-kbQ8NFF5   
Human Protein Atlas [tissue]ENSG00000160688-FLAD1 [tissue]
HPRD17887
Protein Interaction databases
DIP (DOE-UCLA)Q8NFF5
IntAct (EBI)Q8NFF5
BioGRIDFLAD1
STRING (EMBL)FLAD1
ZODIACFLAD1
Ontologies - Pathways
QuickGOQ8NFF5
Ontology : AmiGOFMN adenylyltransferase activity  protein binding  ATP binding  mitochondrial matrix  cytosol  cytosol  plasma membrane  FAD biosynthetic process  FAD biosynthetic process  riboflavin metabolic process  identical protein binding  
Ontology : EGO-EBIFMN adenylyltransferase activity  protein binding  ATP binding  mitochondrial matrix  cytosol  cytosol  plasma membrane  FAD biosynthetic process  FAD biosynthetic process  riboflavin metabolic process  identical protein binding  
Pathways : KEGGRiboflavin metabolism   
NDEx NetworkFLAD1
Atlas of Cancer Signalling NetworkFLAD1
Wikipedia pathwaysFLAD1
Orthology - Evolution
OrthoDB80308
GeneTree (enSembl)ENSG00000160688
Phylogenetic Trees/Animal Genes : TreeFamFLAD1
Homologs : HomoloGeneFLAD1
Homology/Alignments : Family Browser (UCSC)FLAD1
Gene fusions - Rearrangements
Fusion : QuiverFLAD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFLAD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FLAD1
dbVarFLAD1
ClinVarFLAD1
MonarchFLAD1
1000_GenomesFLAD1 
Exome Variant ServerFLAD1
GNOMAD BrowserENSG00000160688
Varsome BrowserFLAD1
ACMGFLAD1 variants
VarityQ8NFF5
Genomic Variants (DGV)FLAD1 [DGVbeta]
DECIPHERFLAD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFLAD1 
Mutations
ICGC Data PortalFLAD1 
TCGA Data PortalFLAD1 
Broad Tumor PortalFLAD1
OASIS PortalFLAD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFLAD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFLAD1
Mutations and Diseases : HGMDFLAD1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFLAD1
DgiDB (Drug Gene Interaction Database)FLAD1
DoCM (Curated mutations)FLAD1
CIViC (Clinical Interpretations of Variants in Cancer)FLAD1
Cancer3DFLAD1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM255100    610595   
Orphanet
DisGeNETFLAD1
MedgenFLAD1
Genetic Testing Registry FLAD1
NextProtQ8NFF5 [Medical]
GENETestsFLAD1
Target ValidationFLAD1
Huge Navigator FLAD1 [HugePedia]
ClinGenFLAD1
Clinical trials, drugs, therapy
MyCancerGenomeFLAD1
Protein Interactions : CTDFLAD1
Pharm GKB GenePA142671759
PharosQ8NFF5
Clinical trialFLAD1
Miscellaneous
canSAR (ICR)FLAD1
HarmonizomeFLAD1
DataMed IndexFLAD1
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFLAD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:50:36 CEST 2021

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