FLI1 (Friend leukemia virus integration 1)

Identity

Other names	EWSR2
	SIC-1
HGNC	FLI1
Location	11q24.1-q24.3
Location_base_pair	Starts at 128069023 and ends at 128188372 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	FLI1   3749
Entrez_Gene	FLI1  2313  Friend leukemia virus integration 1
	Cards
GeneCards	FLI1
Ensembl	FLI1 [Search_View]   ENSG00000151702 [Gene_View]
Genatlas	FLI1
GeneLynx	FLI1
eGenome	FLI1
euGene	2313
	Genomic and cartography
GoldenPath	FLI1  -     chr11:128069023-128188372 +  11q24.3   [Description]    (hg18-March_2006)
Ensembl	FLI1 - 11q24.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	FLI1
	Gene and transcription
Genbank	AF147318 [ ENTREZ ]
Genbank	AI354789 [ ENTREZ ]
Genbank	AK313370 [ ENTREZ ]
Genbank	AY029368 [ ENTREZ ]
Genbank	BC001670 [ ENTREZ ]
RefSeq	NM_002017 [ SRS ]    NM_002017 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	AC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_033899 [ SRS ]    NT_033899 [ ENTREZ ]
RefSeq	NW_001838044 [ SRS ]    NW_001838044 [ ENTREZ ]
RefSeq	NW_925173 [ SRS ]    NW_925173 [ ENTREZ ]
AceView	FLI1 AceView - NCBI
Unigene	Hs.658024 [ SRS ]    Hs.658024 [ NCBI ]     HS658024 [ spliceNest ]
Fast-db	15058 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q01543 [ SRS]    Q01543 [ EXPASY ]     Q01543 [ INTERPRO ]     Q01543 [ UNIPROT ]
Prosite	PS00345 ETS_DOMAIN_1 [ SRS ]    PS00345 ETS_DOMAIN_1 [ Expasy ]
Prosite	PS00346 ETS_DOMAIN_2 [ SRS ]    PS00346 ETS_DOMAIN_2 [ Expasy ]
Prosite	PS50061 ETS_DOMAIN_3 [ SRS ]    PS50061 ETS_DOMAIN_3 [ Expasy ]
Interpro	IPR000418 Ets [ SRS ]    IPR000418 Ets [ EBI ]
Interpro	IPR003118 SAM_PNT [ SRS ]    IPR003118 SAM_PNT [ EBI ]
Interpro	IPR013761 SAM_type [ SRS ]    IPR013761 SAM_type [ EBI ]
Interpro	IPR011991 Wing_hlx_DNA_bd [ SRS ]    IPR011991 Wing_hlx_DNA_bd [ EBI ]
CluSTr	Q01543
Pfam	PF00178 Ets [ SRS ]    PF00178 Ets [ Sanger ]    pfam00178 [ NCBI-CDD ]
Pfam	PF02198 SAM_PNT [ SRS ]    PF02198 SAM_PNT [ Sanger ]    pfam02198 [ NCBI-CDD ]
Smart	SM00413 ETS [EMBL]
Smart	SM00251 SAM_PNT [EMBL]
Blocks	Q01543
PDB	1FLI [ SRS ]    1FLI [ PdbSum ],   1FLI [ IMB ]   1FLI [ RSDB ]
PDB	1X66 [ SRS ]    1X66 [ PdbSum ],   1X66 [ IMB ]   1X66 [ RSDB ]
PDB	2YTU [ SRS ]    2YTU [ PdbSum ],   2YTU [ IMB ]   2YTU [ RSDB ]
HPRD	01901
	Protein Interaction databases
DIP	Q01543
IntAct	Q01543
	Polymorphism : SNP, mutations, diseases
OMIM	193067    [ map ]
GENECLINICS	193067
SNP	FLI1 [dbSNP-NCBI]
SNP	NM_002017 [SNP-NCI]
SNP	FLI1 [GeneSNPs - Utah]  FLI1] [HGBASE - SRS]
HAPMAP	FLI1 [HAPMAP]
COSMIC	FLI1 [Somatic mutation (COSMIC-CGP-Sanger)]
TICdb	transcription [Translocation breakpoints In Cancer]
HGMD	FLI1
	General knowledge
Family Browser	FLI1 [UCSC Family Browser]
SOURCE	NM_002017
SMD	Hs.658024
SAGE	Hs.658024
GO	transcription factor activity [Amigo]  transcription factor activity
GO	nucleus [Amigo]  nucleus
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	hemostasis [Amigo]  hemostasis
GO	organ morphogenesis [Amigo]  organ morphogenesis
GO	sequence-specific DNA binding [Amigo]  sequence-specific DNA binding
PubGene	FLI1
TreeFam	FLI1
CTD	2313 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	FLI1 Related clones (RZPD - Berlin)
	PubMed
PubMed	49 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:41:41 2008