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FLII (FLII, actin remodeling protein)

Identity

Other aliasFLI
FLIL
Fli1
HGNC (Hugo) FLII
LocusID (NCBI) 2314
Atlas_Id 56692
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 18244817 and ends at 18258556 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD99 (Xp22.33) / FLII (17p11.2)EWSR1 (22q12.2) / FLII (17p11.2)FLII (17p11.2) / EWSR1 (22q12.2)
FLII (17p11.2) / FLII (17p11.2)FLII (17p11.2) / SPATA20 (17q21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FLII   3750
Cards
Entrez_Gene (NCBI)FLII  2314  FLII, actin remodeling protein
AliasesFLI; FLIL; Fli1
GeneCards (Weizmann)FLII
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr17:18244817-18258556 [Contig_View]  FLII [Vega]
TCGA cBioPortalFLII
AceView (NCBI)FLII
Genatlas (Paris)FLII
WikiGenes2314
SOURCE (Princeton)FLII
Genetics Home Reference (NIH)FLII
Genomic and cartography
GoldenPath hg38 (UCSC)FLII  -     chr17:18244817-18258556 -  17p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FLII  -     17p11.2   [Description]    (hg19-Feb_2009)
EnsemblFLII - 17p11.2 [CytoView hg19]  FLII - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIFLII [Mapview hg19]  FLII [Mapview hg38]
OMIM600362   
Gene and transcription
Genbank (Entrez)AB208864 AK295655 AK295814 AK297836 AK310400
RefSeq transcript (Entrez)NM_001256264 NM_001256265 NM_002018
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FLII
Cluster EST : UnigeneHs.513984 [ NCBI ]
CGAP (NCI)Hs.513984
Gene ExpressionFLII [ NCBI-GEO ]   FLII [ EBI - ARRAY_EXPRESS ]   FLII [ SEEK ]   FLII [ MEM ]
Gene Expression Viewer (FireBrowse)FLII [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2314
GTEX Portal (Tissue expression)FLII
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13045   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13045  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13045
Splice isoforms : SwissVarQ13045
PhosPhoSitePlusQ13045
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)ADF-H/Gelsolin-like_dom    FliI    Gelsolin-like_dom    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_4    Leu-rich_rpt_typical-subtyp    Villin/Gelsolin   
Domain families : Pfam (Sanger)Gelsolin (PF00626)    LRR_4 (PF12799)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00626    pfam12799    pfam13855   
Domain families : Smart (EMBL)GEL (SM00262)  LRR_TYP (SM00369)  
Conserved Domain (NCBI)FLII
DMDM Disease mutations2314
Blocks (Seattle)FLII
SuperfamilyQ13045
Peptide AtlasQ13045
IPIIPI00031023   IPI00908582   IPI01013074   
Protein Interaction databases
DIP (DOE-UCLA)Q13045
IntAct (EBI)Q13045
BioGRIDFLII
STRING (EMBL)FLII
ZODIACFLII
Ontologies - Pathways
QuickGOQ13045
Ontology : AmiGOactin binding  protein binding  nucleoplasm  microtubule organizing center  cytosol  brush border  focal adhesion  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  actin cytoskeleton organization  actin filament severing  
Ontology : EGO-EBIactin binding  protein binding  nucleoplasm  microtubule organizing center  cytosol  brush border  focal adhesion  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  actin cytoskeleton organization  actin filament severing  
NDEx NetworkFLII
Atlas of Cancer Signalling NetworkFLII
Wikipedia pathwaysFLII
Orthology - Evolution
OrthoDB2314
Phylogenetic Trees/Animal Genes : TreeFamFLII
HOVERGENQ13045
HOGENOMQ13045
Homologs : HomoloGeneFLII
Homology/Alignments : Family Browser (UCSC)FLII
Gene fusions - Rearrangements
Tumor Fusion PortalFLII
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFLII [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FLII
dbVarFLII
ClinVarFLII
1000_GenomesFLII 
Exome Variant ServerFLII
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP2314
Genomic Variants (DGV)FLII [DGVbeta]
DECIPHERFLII [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFLII 
Mutations
ICGC Data PortalFLII 
TCGA Data PortalFLII 
Broad Tumor PortalFLII
OASIS PortalFLII [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFLII  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFLII
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FLII
DgiDB (Drug Gene Interaction Database)FLII
DoCM (Curated mutations)FLII (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FLII (select a term)
intoGenFLII
Cancer3DFLII(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600362   
Orphanet
DisGeNETFLII
MedgenFLII
Genetic Testing Registry FLII
NextProtQ13045 [Medical]
TSGene2314
GENETestsFLII
Target ValidationFLII
Huge Navigator FLII [HugePedia]
snp3D : Map Gene to Disease2314
BioCentury BCIQFLII
ClinGenFLII
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2314
Chemical/Pharm GKB GenePA28171
Clinical trialFLII
Miscellaneous
canSAR (ICR)FLII (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFLII
EVEXFLII
GoPubMedFLII
iHOPFLII
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:13:28 CET 2017

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