Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FLRT1 (fibronectin leucine rich transmembrane protein 1)

Identity

Alias_symbol (synonym)MGC21624
SPG68
Other alias
HGNC (Hugo) FLRT1
LocusID (NCBI) 23769
Atlas_Id 40609
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 64103890 and ends at 64119173 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FLRT1   3760
Cards
Entrez_Gene (NCBI)FLRT1  23769  fibronectin leucine rich transmembrane protein 1
AliasesSPG68
GeneCards (Weizmann)FLRT1
Ensembl hg19 (Hinxton)ENSG00000126500 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126500 [Gene_View]  chr11:64103890-64119173 [Contig_View]  FLRT1 [Vega]
ICGC DataPortalENSG00000126500
TCGA cBioPortalFLRT1
AceView (NCBI)FLRT1
Genatlas (Paris)FLRT1
WikiGenes23769
SOURCE (Princeton)FLRT1
Genetics Home Reference (NIH)FLRT1
Genomic and cartography
GoldenPath hg38 (UCSC)FLRT1  -     chr11:64103890-64119173 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FLRT1  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblFLRT1 - 11q13.1 [CytoView hg19]  FLRT1 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBIFLRT1 [Mapview hg19]  FLRT1 [Mapview hg38]
OMIM604806   
Gene and transcription
Genbank (Entrez)AF007139 AF169675 AK289931 AY358308 BC018370
RefSeq transcript (Entrez)NM_013280
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FLRT1
Cluster EST : UnigeneHs.584876 [ NCBI ]
CGAP (NCI)Hs.584876
Alternative Splicing GalleryENSG00000126500
Gene ExpressionFLRT1 [ NCBI-GEO ]   FLRT1 [ EBI - ARRAY_EXPRESS ]   FLRT1 [ SEEK ]   FLRT1 [ MEM ]
Gene Expression Viewer (FireBrowse)FLRT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23769
GTEX Portal (Tissue expression)FLRT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZU1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZU1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZU1
Splice isoforms : SwissVarQ9NZU1
PhosPhoSitePlusQ9NZU1
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_fold    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)FLRT1
DMDM Disease mutations23769
Blocks (Seattle)FLRT1
SuperfamilyQ9NZU1
Human Protein AtlasENSG00000126500
Peptide AtlasQ9NZU1
HPRD05311
IPIIPI00291395   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZU1
IntAct (EBI)Q9NZU1
FunCoupENSG00000126500
BioGRIDFLRT1
STRING (EMBL)FLRT1
ZODIACFLRT1
Ontologies - Pathways
QuickGOQ9NZU1
Ontology : AmiGOprotein kinase inhibitor activity  signal transducer activity, downstream of receptor  fibroblast growth factor receptor binding  proteinaceous extracellular matrix  extracellular space  cytoplasm  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  negative regulation of protein kinase activity  cell adhesion  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  dendrite development  cytokine-mediated signaling pathway  cytoplasmic vesicle membrane  protein binding, bridging  cytoplasmic vesicle  neuronal cell body membrane  neuron projection terminus  negative regulation of JAK-STAT cascade  perinuclear region of cytoplasm  positive regulation of synapse assembly  neuron projection extension  
Ontology : EGO-EBIprotein kinase inhibitor activity  signal transducer activity, downstream of receptor  fibroblast growth factor receptor binding  proteinaceous extracellular matrix  extracellular space  cytoplasm  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  negative regulation of protein kinase activity  cell adhesion  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  dendrite development  cytokine-mediated signaling pathway  cytoplasmic vesicle membrane  protein binding, bridging  cytoplasmic vesicle  neuronal cell body membrane  neuron projection terminus  negative regulation of JAK-STAT cascade  perinuclear region of cytoplasm  positive regulation of synapse assembly  neuron projection extension  
NDEx NetworkFLRT1
Atlas of Cancer Signalling NetworkFLRT1
Wikipedia pathwaysFLRT1
Orthology - Evolution
OrthoDB23769
GeneTree (enSembl)ENSG00000126500
Phylogenetic Trees/Animal Genes : TreeFamFLRT1
HOVERGENQ9NZU1
HOGENOMQ9NZU1
Homologs : HomoloGeneFLRT1
Homology/Alignments : Family Browser (UCSC)FLRT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFLRT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FLRT1
dbVarFLRT1
ClinVarFLRT1
1000_GenomesFLRT1 
Exome Variant ServerFLRT1
ExAC (Exome Aggregation Consortium)FLRT1 (select the gene name)
Genetic variants : HAPMAP23769
Genomic Variants (DGV)FLRT1 [DGVbeta]
DECIPHERFLRT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFLRT1 
Mutations
ICGC Data PortalFLRT1 
TCGA Data PortalFLRT1 
Broad Tumor PortalFLRT1
OASIS PortalFLRT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFLRT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFLRT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FLRT1
DgiDB (Drug Gene Interaction Database)FLRT1
DoCM (Curated mutations)FLRT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FLRT1 (select a term)
intoGenFLRT1
Cancer3DFLRT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604806   
Orphanet22836   
MedgenFLRT1
Genetic Testing Registry FLRT1
NextProtQ9NZU1 [Medical]
TSGene23769
GENETestsFLRT1
Huge Navigator FLRT1 [HugePedia]
snp3D : Map Gene to Disease23769
BioCentury BCIQFLRT1
ClinGenFLRT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23769
Chemical/Pharm GKB GenePA28177
Clinical trialFLRT1
Miscellaneous
canSAR (ICR)FLRT1 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFLRT1
EVEXFLRT1
GoPubMedFLRT1
iHOPFLRT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:16:08 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.