Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FLRT2 (fibronectin leucine rich transmembrane protein 2)

Identity

Other alias-
HGNC (Hugo) FLRT2
LocusID (NCBI) 23768
Atlas_Id 63540
Location 14q31.3  [Link to chromosome band 14q31]
Location_base_pair Starts at 85996488 and ends at 86094270 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KCNIP4 (4p15.31) / FLRT2 (14q31.3)TSPAN3 (15q24.3) / FLRT2 (14q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FLRT2   3761
Cards
Entrez_Gene (NCBI)FLRT2  23768  fibronectin leucine rich transmembrane protein 2
Aliases
GeneCards (Weizmann)FLRT2
Ensembl hg19 (Hinxton) [Gene_View]  chr14:85996488-86094270 [Contig_View]  FLRT2 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr14:85996488-86094270 [Contig_View]  FLRT2 [Vega]
TCGA cBioPortalFLRT2
AceView (NCBI)FLRT2
Genatlas (Paris)FLRT2
WikiGenes23768
SOURCE (Princeton)FLRT2
Genetics Home Reference (NIH)FLRT2
Genomic and cartography
GoldenPath hg19 (UCSC)FLRT2  -     chr14:85996488-86094270 +  14q31.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FLRT2  -     14q31.3   [Description]    (hg38-Dec_2013)
EnsemblFLRT2 - 14q31.3 [CytoView hg19]  FLRT2 - 14q31.3 [CytoView hg38]
Mapping of homologs : NCBIFLRT2 [Mapview hg19]  FLRT2 [Mapview hg38]
OMIM604807   
Gene and transcription
Genbank (Entrez)AA442817 AF169676 AK056649 AY358287 BC126249
RefSeq transcript (Entrez)NM_013231
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)FLRT2
Cluster EST : UnigeneHs.744139 [ NCBI ]
CGAP (NCI)Hs.744139
Gene ExpressionFLRT2 [ NCBI-GEO ]   FLRT2 [ EBI - ARRAY_EXPRESS ]   FLRT2 [ SEEK ]   FLRT2 [ MEM ]
Gene Expression Viewer (FireBrowse)FLRT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23768
GTEX Portal (Tissue expression)FLRT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43155   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43155  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43155
Splice isoforms : SwissVarO43155
PhosPhoSitePlusO43155
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_fold    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N   
Domain families : Pfam (Sanger)fn3 (PF00041)    LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam00041    pfam13855    pfam01462   
Domain families : Smart (EMBL)FN3 (SM00060)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)FLRT2
DMDM Disease mutations23768
Blocks (Seattle)FLRT2
SuperfamilyO43155
Peptide AtlasO43155
HPRD05312
IPIIPI00001633   IPI01014880   
Protein Interaction databases
DIP (DOE-UCLA)O43155
IntAct (EBI)O43155
BioGRIDFLRT2
STRING (EMBL)FLRT2
ZODIACFLRT2
Ontologies - Pathways
QuickGOO43155
Ontology : AmiGOreceptor signaling protein activity  proteinaceous extracellular matrix  extracellular space  intracellular  integral component of plasma membrane  focal adhesion  cell adhesion  axon guidance  biological_process  protein binding, bridging  intracellular signal transduction  chemorepellent activity  negative chemotaxis  extracellular exosome  regulation of neuron migration  
Ontology : EGO-EBIreceptor signaling protein activity  proteinaceous extracellular matrix  extracellular space  intracellular  integral component of plasma membrane  focal adhesion  cell adhesion  axon guidance  biological_process  protein binding, bridging  intracellular signal transduction  chemorepellent activity  negative chemotaxis  extracellular exosome  regulation of neuron migration  
NDEx NetworkFLRT2
Atlas of Cancer Signalling NetworkFLRT2
Wikipedia pathwaysFLRT2
Orthology - Evolution
OrthoDB23768
Phylogenetic Trees/Animal Genes : TreeFamFLRT2
HOVERGENO43155
HOGENOMO43155
Homologs : HomoloGeneFLRT2
Homology/Alignments : Family Browser (UCSC)FLRT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFLRT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FLRT2
dbVarFLRT2
ClinVarFLRT2
1000_GenomesFLRT2 
Exome Variant ServerFLRT2
ExAC (Exome Aggregation Consortium)FLRT2 (select the gene name)
Genetic variants : HAPMAP23768
Genomic Variants (DGV)FLRT2 [DGVbeta]
DECIPHER (Syndromes)14:85996488-86094270  
CONAN: Copy Number AnalysisFLRT2 
Mutations
ICGC Data PortalFLRT2 
TCGA Data PortalFLRT2 
Broad Tumor PortalFLRT2
OASIS PortalFLRT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFLRT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFLRT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FLRT2
DgiDB (Drug Gene Interaction Database)FLRT2
DoCM (Curated mutations)FLRT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FLRT2 (select a term)
intoGenFLRT2
Cancer3DFLRT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604807   
Orphanet
MedgenFLRT2
Genetic Testing Registry FLRT2
NextProtO43155 [Medical]
TSGene23768
GENETestsFLRT2
Huge Navigator FLRT2 [HugePedia]
snp3D : Map Gene to Disease23768
BioCentury BCIQFLRT2
ClinGenFLRT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23768
Chemical/Pharm GKB GenePA28178
Clinical trialFLRT2
Miscellaneous
canSAR (ICR)FLRT2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFLRT2
EVEXFLRT2
GoPubMedFLRT2
iHOPFLRT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:05:13 CET 2017

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