Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FLRT3 (fibronectin leucine rich transmembrane protein 3)

Identity

Other aliasHH21
HGNC (Hugo) FLRT3
LocusID (NCBI) 23767
Atlas_Id 63541
Location 20p12.1  [Link to chromosome band 20p12]
Location_base_pair Starts at 14323993 and ends at 14337667 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FLRT3   3762
Cards
Entrez_Gene (NCBI)FLRT3  23767  fibronectin leucine rich transmembrane protein 3
AliasesHH21
GeneCards (Weizmann)FLRT3
Ensembl hg19 (Hinxton)ENSG00000125848 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125848 [Gene_View]  chr20:14323993-14337667 [Contig_View]  FLRT3 [Vega]
ICGC DataPortalENSG00000125848
TCGA cBioPortalFLRT3
AceView (NCBI)FLRT3
Genatlas (Paris)FLRT3
WikiGenes23767
SOURCE (Princeton)FLRT3
Genetics Home Reference (NIH)FLRT3
Genomic and cartography
GoldenPath hg38 (UCSC)FLRT3  -     chr20:14323993-14337667 -  20p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FLRT3  -     20p12.1   [Description]    (hg19-Feb_2009)
EnsemblFLRT3 - 20p12.1 [CytoView hg19]  FLRT3 - 20p12.1 [CytoView hg38]
Mapping of homologs : NCBIFLRT3 [Mapview hg19]  FLRT3 [Mapview hg38]
OMIM146110   604808   615271   
Gene and transcription
Genbank (Entrez)AB040902 AF169677 AK027297 AK027670 AK027694
RefSeq transcript (Entrez)NM_013281 NM_198391
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FLRT3
Cluster EST : UnigeneHs.41296 [ NCBI ]
CGAP (NCI)Hs.41296
Alternative Splicing GalleryENSG00000125848
Gene ExpressionFLRT3 [ NCBI-GEO ]   FLRT3 [ EBI - ARRAY_EXPRESS ]   FLRT3 [ SEEK ]   FLRT3 [ MEM ]
Gene Expression Viewer (FireBrowse)FLRT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23767
GTEX Portal (Tissue expression)FLRT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZU0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZU0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZU0
Splice isoforms : SwissVarQ9NZU0
PhosPhoSitePlusQ9NZU0
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_fold    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)FLRT3
DMDM Disease mutations23767
Blocks (Seattle)FLRT3
PDB (SRS)5CMN    5CMP   
PDB (PDBSum)5CMN    5CMP   
PDB (IMB)5CMN    5CMP   
PDB (RSDB)5CMN    5CMP   
Structural Biology KnowledgeBase5CMN    5CMP   
SCOP (Structural Classification of Proteins)5CMN    5CMP   
CATH (Classification of proteins structures)5CMN    5CMP   
SuperfamilyQ9NZU0
Human Protein AtlasENSG00000125848
Peptide AtlasQ9NZU0
HPRD05313
IPIIPI00002320   IPI01011428   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZU0
IntAct (EBI)Q9NZU0
FunCoupENSG00000125848
BioGRIDFLRT3
STRING (EMBL)FLRT3
ZODIACFLRT3
Ontologies - Pathways
QuickGOQ9NZU0
Ontology : AmiGOproepicardium cell migration involved in pericardium morphogenesis  protein kinase inhibitor activity  signal transducer activity, downstream of receptor  fibroblast growth factor receptor binding  protein binding  proteinaceous extracellular matrix  extracellular space  cytoplasm  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  negative regulation of protein kinase activity  axon guidance  synapse assembly  heart development  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  cytokine-mediated signaling pathway  protein binding, bridging  neuron projection development  protein homodimerization activity  axon terminus  axonal growth cone  chemorepellent activity  negative regulation of JAK-STAT cascade  embryonic morphogenesis  response to axon injury  negative chemotaxis  positive regulation of synapse assembly  head development  synaptic membrane  cell-cell adhesion via plasma-membrane adhesion molecules  neuron projection extension  neuron projection extension  
Ontology : EGO-EBIproepicardium cell migration involved in pericardium morphogenesis  protein kinase inhibitor activity  signal transducer activity, downstream of receptor  fibroblast growth factor receptor binding  protein binding  proteinaceous extracellular matrix  extracellular space  cytoplasm  endoplasmic reticulum membrane  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  cell-cell junction  focal adhesion  negative regulation of protein kinase activity  axon guidance  synapse assembly  heart development  fibroblast growth factor receptor signaling pathway  fibroblast growth factor receptor signaling pathway  cytokine-mediated signaling pathway  protein binding, bridging  neuron projection development  protein homodimerization activity  axon terminus  axonal growth cone  chemorepellent activity  negative regulation of JAK-STAT cascade  embryonic morphogenesis  response to axon injury  negative chemotaxis  positive regulation of synapse assembly  head development  synaptic membrane  cell-cell adhesion via plasma-membrane adhesion molecules  neuron projection extension  neuron projection extension  
NDEx NetworkFLRT3
Atlas of Cancer Signalling NetworkFLRT3
Wikipedia pathwaysFLRT3
Orthology - Evolution
OrthoDB23767
GeneTree (enSembl)ENSG00000125848
Phylogenetic Trees/Animal Genes : TreeFamFLRT3
HOVERGENQ9NZU0
HOGENOMQ9NZU0
Homologs : HomoloGeneFLRT3
Homology/Alignments : Family Browser (UCSC)FLRT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFLRT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FLRT3
dbVarFLRT3
ClinVarFLRT3
1000_GenomesFLRT3 
Exome Variant ServerFLRT3
ExAC (Exome Aggregation Consortium)FLRT3 (select the gene name)
Genetic variants : HAPMAP23767
Genomic Variants (DGV)FLRT3 [DGVbeta]
DECIPHERFLRT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFLRT3 
Mutations
ICGC Data PortalFLRT3 
TCGA Data PortalFLRT3 
Broad Tumor PortalFLRT3
OASIS PortalFLRT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFLRT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFLRT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FLRT3
DgiDB (Drug Gene Interaction Database)FLRT3
DoCM (Curated mutations)FLRT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FLRT3 (select a term)
intoGenFLRT3
Cancer3DFLRT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM146110    604808    615271   
Orphanet3249   
MedgenFLRT3
Genetic Testing Registry FLRT3
NextProtQ9NZU0 [Medical]
TSGene23767
GENETestsFLRT3
Target ValidationFLRT3
Huge Navigator FLRT3 [HugePedia]
snp3D : Map Gene to Disease23767
BioCentury BCIQFLRT3
ClinGenFLRT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23767
Chemical/Pharm GKB GenePA28179
Clinical trialFLRT3
Miscellaneous
canSAR (ICR)FLRT3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFLRT3
EVEXFLRT3
GoPubMedFLRT3
iHOPFLRT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:49:41 CEST 2017

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