Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FLT1 (fms related receptor tyrosine kinase 1)

Identity

Alias (NCBI)FLT
FLT-1
VEGFR-1
VEGFR1
HGNC (Hugo) FLT1
HGNC Alias symbVEGFR1
HGNC Alias namevascular endothelial growth factor receptor 1
 vascular permeability factor receptor
HGNC Previous nameFLT
HGNC Previous namefms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
 fms-related tyrosine kinase 1
 fms related tyrosine kinase 1
LocusID (NCBI) 2321
Atlas_Id 40610
Location 13q12.3  [Link to chromosome band 13q12]
Location_base_pair Starts at 28300346 and ends at 28495128 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FLT1 (13q12.3)::CTNND1 (11q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(4;22)(q12;q11) BCR::PDGFRA
+13,+13 or tetrasomy 13


External links

Nomenclature
HGNC (Hugo)FLT1   3763
LRG (Locus Reference Genomic)LRG_425
Cards
Entrez_Gene (NCBI)FLT1    fms related receptor tyrosine kinase 1
AliasesFLT; FLT-1; VEGFR-1; VEGFR1
GeneCards (Weizmann)FLT1
Ensembl hg19 (Hinxton)ENSG00000102755 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102755 [Gene_View]  ENSG00000102755 [Sequence]  chr13:28300346-28495128 [Contig_View]  FLT1 [Vega]
ICGC DataPortalENSG00000102755
TCGA cBioPortalFLT1
AceView (NCBI)FLT1
Genatlas (Paris)FLT1
SOURCE (Princeton)FLT1
Genetics Home Reference (NIH)FLT1
Genomic and cartography
GoldenPath hg38 (UCSC)FLT1  -     chr13:28300346-28495128 -  13q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FLT1  -     13q12.3   [Description]    (hg19-Feb_2009)
GoldenPathFLT1 - 13q12.3 [CytoView hg19]  FLT1 - 13q12.3 [CytoView hg38]
ImmunoBaseENSG00000102755
Genome Data Viewer NCBIFLT1 [Mapview hg19]  
OMIM165070   
Gene and transcription
Genbank (Entrez)AB209050 AF063657 AK092472 AK292936 AK300392
RefSeq transcript (Entrez)NM_001159920 NM_001160030 NM_001160031 NM_002019
Consensus coding sequences : CCDS (NCBI)FLT1
Gene ExpressionFLT1 [ NCBI-GEO ]   FLT1 [ EBI - ARRAY_EXPRESS ]   FLT1 [ SEEK ]   FLT1 [ MEM ]
Gene Expression Viewer (FireBrowse)FLT1 [ Firebrowse - Broad ]
GenevisibleExpression of FLT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2321
GTEX Portal (Tissue expression)FLT1
Human Protein AtlasENSG00000102755-FLT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)FLT1
Human Protein Atlas [tissue]ENSG00000102755-FLT1 [tissue]
HPRD01297
Protein Interaction databases
BioGRIDFLT1
STRING (EMBL)FLT1
ZODIACFLT1
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFLT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Jan 16 18:11:13 CET 2022

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