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FLT3LG (fms-related tyrosine kinase 3 ligand)

Identity

Other namesFL
FLT3L
HGNC (Hugo) FLT3LG
LocusID (NCBI) 2323
Location 19q13.33
Location_base_pair Starts at 49977466 and ends at 49989488 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FLT3LG   3766
Entrez_Gene (NCBI)FLT3LG  2323  fms-related tyrosine kinase 3 ligand
Cards
GeneCards (Weizmann)FLT3LG
Ensembl (Hinxton)ENSG00000090554 [Gene_View]  chr19:49977466-49989488 [Contig_View]  FLT3LG [Vega]
AceView (NCBI)FLT3LG
Genatlas (Paris)FLT3LG
SOURCE (Stanford)NM_001204502 NM_001204503 NM_001459
Genomic and cartography
GoldenPath (UCSC)FLT3LG  -  19q13.33   chr19:49977466-49989488 +  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblFLT3LG - 19q13.33 [CytoView]
Mapping of homologs : NCBIFLT3LG [Mapview]
OMIM600007   
Gene and transcription
Genbank (Entrez)AI792400 AK301136 BC006331 BC011914 BC028001
RefSeq transcript (SRS)NM_001204502 NM_001204503 NM_001459
RefSeq transcript (Entrez)NM_001204502 NM_001204503 NM_001459
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004078099
Consensus coding sequences : CCDS (NCBI)FLT3LG
Cluster EST : UnigeneHs.428 [ SRS ] Hs.428 [ NCBI ]
CGAP (NCI)Hs.428
Alternative Splicing : Fast-db (Paris)GSHG0033321
Alternative Splicing GalleryENSG00000090554
Gene ExpressionFLT3LG [ NCBI-GEO ]   FLT3LG [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49771 (SRS) P49771 (Uniprot)
NextProtP49771
With graphics : InterProP49771
Splice isoforms : SwissVarP49771(Swissvar)
Domains : Interpro (SRS)4_helix_cytokine-like_core    4_helix_cytokine_core    Flt3_lig   
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    Flt3_lig   
Related proteins : CluSTrP49771
Domain families : Pfam (SRS)Flt3_lig (PF02947)   
Domain families : Pfam (Sanger)Flt3_lig (PF02947)   
Domain families : Pfam (NCBI)pfam02947   
DMDM2323
Blocks (Seattle)P49771
PDB (SRS)1ETE    3QS7    3QS9   
PDB (PDBSum)1ETE    3QS7    3QS9   
PDB (IMB)1ETE    3QS7    3QS9   
PDB (RSDB)1ETE    3QS7    3QS9   
Human Protein AtlasENSG00000090554
HPRD02477
IPIIPI00291404   IPI00216372   
Protein Interaction databases
DIP (DOE-UCLA)P49771
IntAct (EBI)P49771
FunCoupENSG00000090554
REACTOMEFLT3LG
Protein Interaction Database2323
BioGRIDFLT3LG
InParanoidP49771
Interologous Interaction database P49771
IntegromeDBFLT3LG
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FLT3LG
SNP (GeneSNP Utah)FLT3LG
SNP : HGBaseFLT3LG
Genetic variants : HAPMAPFLT3LG
Somatic Mutations in Cancer : COSMICFLT3LG 
CONAN: Copy Number AnalysisFLT3LG 
Mutations and Diseases : HGMDFLT3LG
OMIM600007   
GENETests600007   
Disease Genetic AssociationFLT3LG
Huge Navigator FLT3LG [HugePedia]  FLT3LG [HugeCancerGEM]
Genomic VariantsFLT3LG  FLT3LG [DGVbeta]
ClinVarFLT3LG
snp3D : Map Gene to Disease2323
General knowledge
Homologs : HomoloGeneFLT3LG
Homology/Alignments : Family Browser (UCSC)FLT3LG
Phylogenetic Trees/Animal Genes : TreeFamFLT3LG
Chemical/Protein Interactions : CTD2323
Chemical/Pharm GKB GenePA28182
Clinical trialFLT3LG
Cancer Resource (Charite)ENSG00000090554
Ontology : AmiGOreceptor binding  cytokine activity  extracellular space  plasma membrane  signal transduction  positive regulation of cell proliferation  membrane  integral to membrane  embryonic hemopoiesis  
Ontology : EGO-EBIreceptor binding  cytokine activity  extracellular space  plasma membrane  signal transduction  positive regulation of cell proliferation  membrane  integral to membrane  embryonic hemopoiesis  
Pathways : KEGGCytokine-cytokine receptor interactionHematopoietic cell lineage
Other databases
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
PubGeneFLT3LG
iHOPFLT3LG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:43:13 CEST 2013
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