Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FLT3LG (fms-related tyrosine kinase 3 ligand)

Identity

Other namesFL
FLT3L
HGNC (Hugo) FLT3LG
LocusID (NCBI) 2323
Location 19q13.33
Location_base_pair Starts at 49977466 and ends at 49989488 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FLT3LG   3766
Cards
Entrez_Gene (NCBI)FLT3LG  2323  fms-related tyrosine kinase 3 ligand
GeneCards (Weizmann)FLT3LG
Ensembl (Hinxton)ENSG00000090554 [Gene_View]  chr19:49977466-49989488 [Contig_View]  FLT3LG [Vega]
ICGC DataPortalENSG00000090554
cBioPortalFLT3LG
AceView (NCBI)FLT3LG
Genatlas (Paris)FLT3LG
WikiGenes2323
SOURCE (Princeton)NM_001204502 NM_001204503 NM_001278637 NM_001278638 NM_001459
Genomic and cartography
GoldenPath (UCSC)FLT3LG  -  19q13.33   chr19:49977466-49989488 +  19q13.33   [Description]    (hg19-Feb_2009)
EnsemblFLT3LG - 19q13.33 [CytoView]
Mapping of homologs : NCBIFLT3LG [Mapview]
OMIM600007   
Gene and transcription
Genbank (Entrez)AI792400 AK301136 BC006331 BC011914 BC028001
RefSeq transcript (Entrez)NM_001204502 NM_001204503 NM_001278637 NM_001278638 NM_001459
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011109 NW_001838497 NW_004929415
Consensus coding sequences : CCDS (NCBI)FLT3LG
Cluster EST : UnigeneHs.428 [ NCBI ]
CGAP (NCI)Hs.428
Alternative Splicing : Fast-db (Paris)GSHG0033321
Alternative Splicing GalleryENSG00000090554
Gene ExpressionFLT3LG [ NCBI-GEO ]     FLT3LG [ SEEK ]   FLT3LG [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49771 (Uniprot)
NextProtP49771  [Medical]
With graphics : InterProP49771
Splice isoforms : SwissVarP49771 (Swissvar)
Domains : Interpro (EBI)4_helix_cytokine-like_core [organisation]   4_helix_cytokine_core [organisation]   Flt3_lig [organisation]  
Related proteins : CluSTrP49771
Domain families : Pfam (Sanger)Flt3_lig (PF02947)   
Domain families : Pfam (NCBI)pfam02947   
DMDM Disease mutations2323
Blocks (Seattle)P49771
PDB (SRS)1ETE    3QS7    3QS9   
PDB (PDBSum)1ETE    3QS7    3QS9   
PDB (IMB)1ETE    3QS7    3QS9   
PDB (RSDB)1ETE    3QS7    3QS9   
Human Protein AtlasENSG00000090554 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP49771
HPRD02477
IPIIPI00291404   IPI00216372   
Protein Interaction databases
DIP (DOE-UCLA)P49771
IntAct (EBI)P49771
FunCoupENSG00000090554
BioGRIDFLT3LG
InParanoidP49771
Interologous Interaction database P49771
IntegromeDBFLT3LG
STRING (EMBL)FLT3LG
Ontologies - Pathways
Ontology : AmiGOreceptor binding  cytokine activity  extracellular space  signal transduction  positive regulation of cell proliferation  membrane  integral component of membrane  lymphocyte differentiation  receptor tyrosine kinase binding  intrinsic component of external side of plasma membrane  positive regulation of natural killer cell differentiation  embryonic hemopoiesis  protein homodimerization activity  
Ontology : EGO-EBIreceptor binding  cytokine activity  extracellular space  signal transduction  positive regulation of cell proliferation  membrane  integral component of membrane  lymphocyte differentiation  receptor tyrosine kinase binding  intrinsic component of external side of plasma membrane  positive regulation of natural killer cell differentiation  embryonic hemopoiesis  protein homodimerization activity  
Pathways : KEGGCytokine-cytokine receptor interaction    Hematopoietic cell lineage    Pathways in cancer   
Protein Interaction DatabaseFLT3LG
Wikipedia pathwaysFLT3LG
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FLT3LG
snp3D : Map Gene to Disease2323
SNP (GeneSNP Utah)FLT3LG
SNP : HGBaseFLT3LG
Genetic variants : HAPMAPFLT3LG
Exome VariantFLT3LG
1000_GenomesFLT3LG 
ICGC programENSG00000090554 
Somatic Mutations in Cancer : COSMICFLT3LG 
CONAN: Copy Number AnalysisFLT3LG 
Mutations and Diseases : HGMDFLT3LG
Mutations and Diseases : intOGenFLT3LG
Genomic VariantsFLT3LG  FLT3LG [DGVbeta]
dbVarFLT3LG
ClinVarFLT3LG
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM600007   
MedgenFLT3LG
GENETestsFLT3LG
Disease Genetic AssociationFLT3LG
Huge Navigator FLT3LG [HugePedia]  FLT3LG [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneFLT3LG
Homology/Alignments : Family Browser (UCSC)FLT3LG
Phylogenetic Trees/Animal Genes : TreeFamFLT3LG
Chemical/Protein Interactions : CTD2323
Chemical/Pharm GKB GenePA28182
Clinical trialFLT3LG
Cancer Resource (Charite)ENSG00000090554
Other databases
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
CoreMineFLT3LG
iHOPFLT3LG
OncoSearchFLT3LG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:51:39 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.