Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FMN1 (formin 1)

Identity

Alias_namesLD
FMN
formin (limb deformity)
Alias_symbol (synonym)DKFZP686C2281
FLJ45135
MGC125288
MGC125289
Other alias
HGNC (Hugo) FMN1
LocusID (NCBI) 342184
Atlas_Id 51634
Location 15q13.3  [Link to chromosome band 15q13]
Location_base_pair Starts at 32765544 and ends at 33068032 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTB (7p22.1) / FMN1 (15q13.3)FMN1 (15q13.3) / ATP5B (12q13.3)ITGB3 (17q21.32) / FMN1 (15q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FMN1   3768
Cards
Entrez_Gene (NCBI)FMN1  342184  formin 1
AliasesFMN; LD
GeneCards (Weizmann)FMN1
Ensembl hg19 (Hinxton)ENSG00000248905 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000248905 [Gene_View]  chr15:32765544-33068032 [Contig_View]  FMN1 [Vega]
ICGC DataPortalENSG00000248905
TCGA cBioPortalFMN1
AceView (NCBI)FMN1
Genatlas (Paris)FMN1
WikiGenes342184
SOURCE (Princeton)FMN1
Genetics Home Reference (NIH)FMN1
Genomic and cartography
GoldenPath hg38 (UCSC)FMN1  -     chr15:32765544-33068032 -  15q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMN1  -     15q13.3   [Description]    (hg19-Feb_2009)
EnsemblFMN1 - 15q13.3 [CytoView hg19]  FMN1 - 15q13.3 [CytoView hg38]
Mapping of homologs : NCBIFMN1 [Mapview hg19]  FMN1 [Mapview hg38]
OMIM136535   
Gene and transcription
Genbank (Entrez)AI040235 AI417633 AL833157 BC029107 BC101971
RefSeq transcript (Entrez)NM_001103184 NM_001277313 NM_001277314 NM_198500
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_042863 NT_187660 NW_011332701 NW_012132920
Consensus coding sequences : CCDS (NCBI)FMN1
Cluster EST : UnigeneHs.657649 [ NCBI ]
CGAP (NCI)Hs.657649
Alternative Splicing GalleryENSG00000248905
Gene ExpressionFMN1 [ NCBI-GEO ]   FMN1 [ EBI - ARRAY_EXPRESS ]   FMN1 [ SEEK ]   FMN1 [ MEM ]
Gene Expression Viewer (FireBrowse)FMN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)342184
GTEX Portal (Tissue expression)FMN1
Human Protein AtlasENSG00000248905-FMN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68DA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68DA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68DA7
Splice isoforms : SwissVarQ68DA7
PhosPhoSitePlusQ68DA7
Domaine pattern : Prosite (Expaxy)FH2 (PS51444)   
Domains : Interpro (EBI)FH2_Formin    Formin_Cappuccino_subfam   
Domain families : Pfam (Sanger)FH2 (PF02181)   
Domain families : Pfam (NCBI)pfam02181   
Domain families : Smart (EMBL)FH2 (SM00498)  
Conserved Domain (NCBI)FMN1
DMDM Disease mutations342184
Blocks (Seattle)FMN1
SuperfamilyQ68DA7
Human Protein Atlas [tissue]ENSG00000248905-FMN1 [tissue]
Peptide AtlasQ68DA7
HPRD07031
IPIIPI00854651   IPI00470874   IPI00889693   IPI00740336   
Protein Interaction databases
DIP (DOE-UCLA)Q68DA7
IntAct (EBI)Q68DA7
FunCoupENSG00000248905
BioGRIDFMN1
STRING (EMBL)FMN1
ZODIACFMN1
Ontologies - Pathways
QuickGOQ68DA7
Ontology : AmiGOactin binding  nucleus  cytoplasm  actin filament  plasma membrane  adherens junction  microtubule binding  gene expression  microtubule cytoskeleton  SH3 domain binding  forelimb morphogenesis  hindlimb morphogenesis  actin nucleation  skeletal system morphogenesis  dendrite morphogenesis  positive regulation of actin nucleation  positive regulation of focal adhesion assembly  ureteric bud invasion  
Ontology : EGO-EBIactin binding  nucleus  cytoplasm  actin filament  plasma membrane  adherens junction  microtubule binding  gene expression  microtubule cytoskeleton  SH3 domain binding  forelimb morphogenesis  hindlimb morphogenesis  actin nucleation  skeletal system morphogenesis  dendrite morphogenesis  positive regulation of actin nucleation  positive regulation of focal adhesion assembly  ureteric bud invasion  
NDEx NetworkFMN1
Atlas of Cancer Signalling NetworkFMN1
Wikipedia pathwaysFMN1
Orthology - Evolution
OrthoDB342184
GeneTree (enSembl)ENSG00000248905
Phylogenetic Trees/Animal Genes : TreeFamFMN1
HOVERGENQ68DA7
HOGENOMQ68DA7
Homologs : HomoloGeneFMN1
Homology/Alignments : Family Browser (UCSC)FMN1
Gene fusions - Rearrangements
Fusion: Tumor Portal FMN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FMN1
dbVarFMN1
ClinVarFMN1
1000_GenomesFMN1 
Exome Variant ServerFMN1
ExAC (Exome Aggregation Consortium)ENSG00000248905
GNOMAD BrowserENSG00000248905
Genetic variants : HAPMAP342184
Genomic Variants (DGV)FMN1 [DGVbeta]
DECIPHERFMN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMN1 
Mutations
ICGC Data PortalFMN1 
TCGA Data PortalFMN1 
Broad Tumor PortalFMN1
OASIS PortalFMN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFMN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FMN1
DgiDB (Drug Gene Interaction Database)FMN1
DoCM (Curated mutations)FMN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FMN1 (select a term)
intoGenFMN1
Cancer3DFMN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM136535   
Orphanet
MedgenFMN1
Genetic Testing Registry FMN1
NextProtQ68DA7 [Medical]
TSGene342184
GENETestsFMN1
Target ValidationFMN1
Huge Navigator FMN1 [HugePedia]
snp3D : Map Gene to Disease342184
BioCentury BCIQFMN1
ClinGenFMN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD342184
Chemical/Pharm GKB GenePA28184
Clinical trialFMN1
Miscellaneous
canSAR (ICR)FMN1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFMN1
EVEXFMN1
GoPubMedFMN1
iHOPFMN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:50:14 CET 2017

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