FMN1 (formin 1)

2010-08-01  

Identity

HGNC
FMN1
LOCATION
15q13.3
LOCUSID
342184
ALIAS
FMN,LD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 342184
MIM: 136535
HGNC: 3768
Ensembl: ENSG00000248905

Variants:

dbSNP: 342184
ClinVar: 342184
TCGA: ENSG00000248905
COSMIC: FMN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000248905ENST00000320930Q68DA7
ENSG00000248905ENST00000334528Q68DA7
ENSG00000248905ENST00000558197Q68DA7
ENSG00000248905ENST00000558711H0YMP0
ENSG00000248905ENST00000559610H0YL93
ENSG00000248905ENST00000560317H0YLM7
ENSG00000248905ENST00000561249H0YM30
ENSG00000248905ENST00000616417Q68DA7

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
retina
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
219755492011Filopodia initiation: focus on the Arp2/3 complex and formins.60
196053602009Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins.28
206104402010Genomic rearrangements of the GREM1-FMN1 locus cause oligosyndactyly, radio-ulnar synostosis, hearing loss, renal defects syndrome and Cenani--Lenz-like non-syndromic oligosyndactyly.9
202009782010Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.7
190961302008Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.3
205403602010[A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer].1
205403602010[A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer].1
303096552018Mechanostress resistance involving formin homology proteins: G- and F-actin homeostasis-driven filament nucleation and helical polymerization-mediated actin polymer stabilization.1
277993672016Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse.0

Citation

Dessen P

FMN1 (formin 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51634/fmn1