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FMO2 (flavin containing monooxygenase 2)

Identity

Alias_namesflavin containing monooxygenase 2 (non-functional)
Other aliasFMO1B1
HGNC (Hugo) FMO2
LocusID (NCBI) 2327
Atlas_Id 63545
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 171185208 and ends at 171212683 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FMO2 (1q24.3) / FMO2 (1q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FMO2   3770
Cards
Entrez_Gene (NCBI)FMO2  2327  flavin containing monooxygenase 2
AliasesFMO1B1
GeneCards (Weizmann)FMO2
Ensembl hg19 (Hinxton)ENSG00000094963 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000094963 [Gene_View]  chr1:171185208-171212683 [Contig_View]  FMO2 [Vega]
ICGC DataPortalENSG00000094963
TCGA cBioPortalFMO2
AceView (NCBI)FMO2
Genatlas (Paris)FMO2
WikiGenes2327
SOURCE (Princeton)FMO2
Genetics Home Reference (NIH)FMO2
Genomic and cartography
GoldenPath hg38 (UCSC)FMO2  -     chr1:171185208-171212683 +  1q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMO2  -     1q24.3   [Description]    (hg19-Feb_2009)
EnsemblFMO2 - 1q24.3 [CytoView hg19]  FMO2 - 1q24.3 [CytoView hg38]
Mapping of homologs : NCBIFMO2 [Mapview hg19]  FMO2 [Mapview hg38]
OMIM603955   
Gene and transcription
Genbank (Entrez)AI821378 AK098145 AK304385 AK312877 AL833218
RefSeq transcript (Entrez)NM_001301347 NM_001460
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FMO2
Cluster EST : UnigeneHs.144912 [ NCBI ]
CGAP (NCI)Hs.144912
Alternative Splicing GalleryENSG00000094963
Gene ExpressionFMO2 [ NCBI-GEO ]   FMO2 [ EBI - ARRAY_EXPRESS ]   FMO2 [ SEEK ]   FMO2 [ MEM ]
Gene Expression Viewer (FireBrowse)FMO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2327
GTEX Portal (Tissue expression)FMO2
Human Protein AtlasENSG00000094963-FMO2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99518   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99518  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99518
Splice isoforms : SwissVarQ99518
Catalytic activity : Enzyme1.14.13.8 [ Enzyme-Expasy ]   1.14.13.81.14.13.8 [ IntEnz-EBI ]   1.14.13.8 [ BRENDA ]   1.14.13.8 [ KEGG ]   
PhosPhoSitePlusQ99518
Domains : Interpro (EBI)DiMe-aniline_mOase    FAD/NAD-binding_dom    Flavin_mOase    Flavin_mOase-like    Flavin_mOase_2   
Domain families : Pfam (Sanger)FMO-like (PF00743)   
Domain families : Pfam (NCBI)pfam00743   
Conserved Domain (NCBI)FMO2
DMDM Disease mutations2327
Blocks (Seattle)FMO2
SuperfamilyQ99518
Human Protein Atlas [tissue]ENSG00000094963-FMO2 [tissue]
Peptide AtlasQ99518
HPRD04903
IPIIPI00016005   
Protein Interaction databases
DIP (DOE-UCLA)Q99518
IntAct (EBI)Q99518
FunCoupENSG00000094963
BioGRIDFMO2
STRING (EMBL)FMO2
ZODIACFMO2
Ontologies - Pathways
QuickGOQ99518
Ontology : AmiGOmonooxygenase activity  N,N-dimethylaniline monooxygenase activity  endoplasmic reticulum membrane  organic acid metabolic process  NADP metabolic process  xenobiotic metabolic process  xenobiotic metabolic process  toxin metabolic process  membrane  integral component of membrane  drug metabolic process  organelle membrane  flavin adenine dinucleotide binding  NADP binding  NADPH oxidation  oxygen metabolic process  
Ontology : EGO-EBImonooxygenase activity  N,N-dimethylaniline monooxygenase activity  endoplasmic reticulum membrane  organic acid metabolic process  NADP metabolic process  xenobiotic metabolic process  xenobiotic metabolic process  toxin metabolic process  membrane  integral component of membrane  drug metabolic process  organelle membrane  flavin adenine dinucleotide binding  NADP binding  NADPH oxidation  oxygen metabolic process  
Pathways : KEGGDrug metabolism - cytochrome P450   
NDEx NetworkFMO2
Atlas of Cancer Signalling NetworkFMO2
Wikipedia pathwaysFMO2
Orthology - Evolution
OrthoDB2327
GeneTree (enSembl)ENSG00000094963
Phylogenetic Trees/Animal Genes : TreeFamFMO2
HOVERGENQ99518
HOGENOMQ99518
Homologs : HomoloGeneFMO2
Homology/Alignments : Family Browser (UCSC)FMO2
Gene fusions - Rearrangements
Fusion: Tumor Portal FMO2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FMO2
dbVarFMO2
ClinVarFMO2
1000_GenomesFMO2 
Exome Variant ServerFMO2
ExAC (Exome Aggregation Consortium)ENSG00000094963
GNOMAD BrowserENSG00000094963
Genetic variants : HAPMAP2327
Genomic Variants (DGV)FMO2 [DGVbeta]
DECIPHERFMO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMO2 
Mutations
ICGC Data PortalFMO2 
TCGA Data PortalFMO2 
Broad Tumor PortalFMO2
OASIS PortalFMO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFMO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FMO2
DgiDB (Drug Gene Interaction Database)FMO2
DoCM (Curated mutations)FMO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FMO2 (select a term)
intoGenFMO2
Cancer3DFMO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603955   
Orphanet
MedgenFMO2
Genetic Testing Registry FMO2
NextProtQ99518 [Medical]
TSGene2327
GENETestsFMO2
Target ValidationFMO2
Huge Navigator FMO2 [HugePedia]
snp3D : Map Gene to Disease2327
BioCentury BCIQFMO2
ClinGenFMO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2327
Chemical/Pharm GKB GenePA164741534
Clinical trialFMO2
Miscellaneous
canSAR (ICR)FMO2 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFMO2
EVEXFMO2
GoPubMedFMO2
iHOPFMO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:48:11 CET 2017

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