Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FMOD (fibromodulin)

Identity

Alias_symbol (synonym)SLRR2E
Other aliasFM
HGNC (Hugo) FMOD
LocusID (NCBI) 2331
Atlas_Id 40616
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203340621 and ends at 203351429 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FMOD (1q32.1) / FMOD (1q32.1)POGK (1q24.1) / FMOD (1q32.1)POGK 1q24.1 / FMOD 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;1)(q24;q32) POGK/FMOD

External links

Nomenclature
HGNC (Hugo)FMOD   3774
Cards
Entrez_Gene (NCBI)FMOD  2331  fibromodulin
AliasesFM; SLRR2E
GeneCards (Weizmann)FMOD
Ensembl hg19 (Hinxton)ENSG00000122176 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122176 [Gene_View]  chr1:203340621-203351429 [Contig_View]  FMOD [Vega]
ICGC DataPortalENSG00000122176
TCGA cBioPortalFMOD
AceView (NCBI)FMOD
Genatlas (Paris)FMOD
WikiGenes2331
SOURCE (Princeton)FMOD
Genetics Home Reference (NIH)FMOD
Genomic and cartography
GoldenPath hg38 (UCSC)FMOD  -     chr1:203340621-203351429 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMOD  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblFMOD - 1q32.1 [CytoView hg19]  FMOD - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIFMOD [Mapview hg19]  FMOD [Mapview hg38]
OMIM600245   
Gene and transcription
Genbank (Entrez)AK092899 AK098322 AK172740 AK291632 AK303866
RefSeq transcript (Entrez)NM_002023
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FMOD
Cluster EST : UnigeneHs.519168 [ NCBI ]
CGAP (NCI)Hs.519168
Alternative Splicing GalleryENSG00000122176
Gene ExpressionFMOD [ NCBI-GEO ]   FMOD [ EBI - ARRAY_EXPRESS ]   FMOD [ SEEK ]   FMOD [ MEM ]
Gene Expression Viewer (FireBrowse)FMOD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2331
GTEX Portal (Tissue expression)FMOD
Human Protein AtlasENSG00000122176-FMOD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06828   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06828  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06828
Splice isoforms : SwissVarQ06828
PhosPhoSitePlusQ06828
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Fibromodulin    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)FMOD
DMDM Disease mutations2331
Blocks (Seattle)FMOD
SuperfamilyQ06828
Human Protein Atlas [tissue]ENSG00000122176-FMOD [tissue]
Peptide AtlasQ06828
HPRD02591
IPIIPI00000860   IPI01011097   IPI00942466   IPI00745150   
Protein Interaction databases
DIP (DOE-UCLA)Q06828
IntAct (EBI)Q06828
FunCoupENSG00000122176
BioGRIDFMOD
STRING (EMBL)FMOD
ZODIACFMOD
Ontologies - Pathways
QuickGOQ06828
Ontology : AmiGOextracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  Golgi lumen  transforming growth factor beta receptor complex assembly  axonogenesis  keratan sulfate biosynthetic process  collagen fibril organization  extracellular matrix  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  
Ontology : EGO-EBIextracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  Golgi lumen  transforming growth factor beta receptor complex assembly  axonogenesis  keratan sulfate biosynthetic process  collagen fibril organization  extracellular matrix  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  
Pathways : BIOCARTASmall Leucine-rich Proteoglycan (SLRP) molecules [Genes]   
NDEx NetworkFMOD
Atlas of Cancer Signalling NetworkFMOD
Wikipedia pathwaysFMOD
Orthology - Evolution
OrthoDB2331
GeneTree (enSembl)ENSG00000122176
Phylogenetic Trees/Animal Genes : TreeFamFMOD
HOVERGENQ06828
HOGENOMQ06828
Homologs : HomoloGeneFMOD
Homology/Alignments : Family Browser (UCSC)FMOD
Gene fusions - Rearrangements
Fusion : MitelmanPOGK/FMOD [1q24.1/1q32.1]  [t(1;1)(q24;q32)]  
Fusion: TCGA_MDACCPOGK 1q24.1 FMOD 1q32.1 BRCA
Fusion PortalPOGK 1q24.1 FMOD 1q32.1 BRCA
Fusion : QuiverFMOD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMOD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FMOD
dbVarFMOD
ClinVarFMOD
1000_GenomesFMOD 
Exome Variant ServerFMOD
ExAC (Exome Aggregation Consortium)ENSG00000122176
GNOMAD BrowserENSG00000122176
Genetic variants : HAPMAP2331
Genomic Variants (DGV)FMOD [DGVbeta]
DECIPHERFMOD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMOD 
Mutations
ICGC Data PortalFMOD 
TCGA Data PortalFMOD 
Broad Tumor PortalFMOD
OASIS PortalFMOD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMOD  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFMOD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FMOD
DgiDB (Drug Gene Interaction Database)FMOD
DoCM (Curated mutations)FMOD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FMOD (select a term)
intoGenFMOD
Cancer3DFMOD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600245   
Orphanet
DisGeNETFMOD
MedgenFMOD
Genetic Testing Registry FMOD
NextProtQ06828 [Medical]
TSGene2331
GENETestsFMOD
Target ValidationFMOD
Huge Navigator FMOD [HugePedia]
snp3D : Map Gene to Disease2331
BioCentury BCIQFMOD
ClinGenFMOD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2331
Chemical/Pharm GKB GenePA28190
Clinical trialFMOD
Miscellaneous
canSAR (ICR)FMOD (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFMOD
EVEXFMOD
GoPubMedFMOD
iHOPFMOD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon May 14 11:46:27 CEST 2018
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.