Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FMOD (fibromodulin)

Identity

Alias (NCBI)FM
SLRR2E
HGNC (Hugo) FMOD
HGNC Alias symbSLRR2E
HGNC Alias namefibromodulin proteoglycan
LocusID (NCBI) 2331
Atlas_Id 40616
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203340628 and ends at 203351122 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FMOD (1q32.1) / FMOD (1q32.1)POGK (1q24.1) / FMOD (1q32.1)POGK 1q24.1 / FMOD 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;1)(q24;q32) POGK/FMOD

External links

Nomenclature
HGNC (Hugo)FMOD   3774
Cards
Entrez_Gene (NCBI)FMOD    fibromodulin
AliasesFM; SLRR2E
GeneCards (Weizmann)FMOD
Ensembl hg19 (Hinxton)ENSG00000122176 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122176 [Gene_View]  ENSG00000122176 [Sequence]  chr1:203340628-203351122 [Contig_View]  FMOD [Vega]
ICGC DataPortalENSG00000122176
TCGA cBioPortalFMOD
AceView (NCBI)FMOD
Genatlas (Paris)FMOD
SOURCE (Princeton)FMOD
Genetics Home Reference (NIH)FMOD
Genomic and cartography
GoldenPath hg38 (UCSC)FMOD  -     chr1:203340628-203351122 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMOD  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathFMOD - 1q32.1 [CytoView hg19]  FMOD - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000122176
genome Data Viewer NCBIFMOD [Mapview hg19]  
OMIM600245   
Gene and transcription
Genbank (Entrez)AK092899 AK098322 AK172740 AK291632 AK303866
RefSeq transcript (Entrez)NM_002023
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FMOD
Alternative Splicing GalleryENSG00000122176
Gene ExpressionFMOD [ NCBI-GEO ]   FMOD [ EBI - ARRAY_EXPRESS ]   FMOD [ SEEK ]   FMOD [ MEM ]
Gene Expression Viewer (FireBrowse)FMOD [ Firebrowse - Broad ]
GenevisibleExpression of FMOD in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2331
GTEX Portal (Tissue expression)FMOD
Human Protein AtlasENSG00000122176-FMOD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06828   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06828  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06828
Splice isoforms : SwissVarQ06828
PhosPhoSitePlusQ06828
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Fibromodulin    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)FMOD
Blocks (Seattle)FMOD
PDB (RSDB)5MX0   
PDB Europe5MX0   
PDB (PDBSum)5MX0   
PDB (IMB)5MX0   
Structural Biology KnowledgeBase5MX0   
SCOP (Structural Classification of Proteins)5MX0   
CATH (Classification of proteins structures)5MX0   
SuperfamilyQ06828
Human Protein Atlas [tissue]ENSG00000122176-FMOD [tissue]
Peptide AtlasQ06828
HPRD02591
IPIIPI00000860   IPI01011097   IPI00942466   IPI00745150   
Protein Interaction databases
DIP (DOE-UCLA)Q06828
IntAct (EBI)Q06828
BioGRIDFMOD
STRING (EMBL)FMOD
ZODIACFMOD
Ontologies - Pathways
QuickGOQ06828
Ontology : AmiGOextracellular region  extracellular region  extracellular space  extracellular space  Golgi lumen  transforming growth factor beta receptor complex assembly  keratan sulfate biosynthetic process  extracellular matrix structural constituent conferring compression resistance  collagen fibril organization  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  collagen-containing extracellular matrix  collagen-containing extracellular matrix  
Ontology : EGO-EBIextracellular region  extracellular region  extracellular space  extracellular space  Golgi lumen  transforming growth factor beta receptor complex assembly  keratan sulfate biosynthetic process  extracellular matrix structural constituent conferring compression resistance  collagen fibril organization  extracellular matrix  keratan sulfate catabolic process  lysosomal lumen  collagen-containing extracellular matrix  collagen-containing extracellular matrix  
NDEx NetworkFMOD
Atlas of Cancer Signalling NetworkFMOD
Wikipedia pathwaysFMOD
Orthology - Evolution
OrthoDB2331
GeneTree (enSembl)ENSG00000122176
Phylogenetic Trees/Animal Genes : TreeFamFMOD
HOGENOMQ06828
Homologs : HomoloGeneFMOD
Homology/Alignments : Family Browser (UCSC)FMOD
Gene fusions - Rearrangements
Fusion : MitelmanPOGK/FMOD [1q24.1/1q32.1]  
Fusion PortalPOGK 1q24.1 FMOD 1q32.1 BRCA
Fusion : QuiverFMOD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMOD [hg38]
dbVarFMOD
ClinVarFMOD
MonarchFMOD
1000_GenomesFMOD 
Exome Variant ServerFMOD
GNOMAD BrowserENSG00000122176
Varsome BrowserFMOD
Genomic Variants (DGV)FMOD [DGVbeta]
DECIPHERFMOD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMOD 
Mutations
ICGC Data PortalFMOD 
TCGA Data PortalFMOD 
Broad Tumor PortalFMOD
OASIS PortalFMOD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMOD  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFMOD
Mutations and Diseases : HGMDFMOD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FMOD
DgiDB (Drug Gene Interaction Database)FMOD
DoCM (Curated mutations)FMOD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FMOD (select a term)
intoGenFMOD
Cancer3DFMOD(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600245   
Orphanet
DisGeNETFMOD
MedgenFMOD
Genetic Testing Registry FMOD
NextProtQ06828 [Medical]
GENETestsFMOD
Target ValidationFMOD
Huge Navigator FMOD [HugePedia]
ClinGenFMOD
Clinical trials, drugs, therapy
MyCancerGenomeFMOD
Protein Interactions : CTD
Pharm GKB GenePA28190
PharosQ06828
Clinical trialFMOD
Miscellaneous
canSAR (ICR)FMOD (select the gene name)
HarmonizomeFMOD
DataMed IndexFMOD
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFMOD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:15:57 CET 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.