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FN3KRP (fructosamine 3 kinase related protein)

Identity

Alias_symbol (synonym)FLJ12171
FN3KL
Other alias
HGNC (Hugo) FN3KRP
LocusID (NCBI) 79672
Atlas_Id 43909
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 82716706 and ends at 82728017 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GOLGA2 (9q34.11) / FN3KRP (17q25.3)REV3L (6q21) / FN3KRP (17q25.3)WSB1 (17q11.1) / FN3KRP (17q25.3)
ZSWIM4 (19p13.13) / FN3KRP (17q25.3)REV3L 6q21 / FN3KRP 17q25.3WSB1 17q11.1 / FN3KRP 17q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(6;17)(q21;q25) REV3L/FN3KRP
t(11;17)(p15;q25) FN3KRP/KCNQ1
t(17;17)(q11;q25) WSB1/FN3KRP

External links

Nomenclature
HGNC (Hugo)FN3KRP   25700
Cards
Entrez_Gene (NCBI)FN3KRP  79672  fructosamine 3 kinase related protein
AliasesFN3KL
GeneCards (Weizmann)FN3KRP
Ensembl hg19 (Hinxton)ENSG00000141560 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000141560 [Gene_View]  ENSG00000141560 [Sequence]  chr17:82716706-82728017 [Contig_View]  FN3KRP [Vega]
ICGC DataPortalENSG00000141560
TCGA cBioPortalFN3KRP
AceView (NCBI)FN3KRP
Genatlas (Paris)FN3KRP
WikiGenes79672
SOURCE (Princeton)FN3KRP
Genetics Home Reference (NIH)FN3KRP
Genomic and cartography
GoldenPath hg38 (UCSC)FN3KRP  -     chr17:82716706-82728017 +  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FN3KRP  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblFN3KRP - 17q25.3 [CytoView hg19]  FN3KRP - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIFN3KRP [Mapview hg19]  FN3KRP [Mapview hg38]
OMIM611683   
Gene and transcription
Genbank (Entrez)AA766235 AK022233 AK293523 AK301958 AK315373
RefSeq transcript (Entrez)NM_024619
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FN3KRP
Cluster EST : UnigeneHs.31431 [ NCBI ]
CGAP (NCI)Hs.31431
Alternative Splicing GalleryENSG00000141560
Gene ExpressionFN3KRP [ NCBI-GEO ]   FN3KRP [ EBI - ARRAY_EXPRESS ]   FN3KRP [ SEEK ]   FN3KRP [ MEM ]
Gene Expression Viewer (FireBrowse)FN3KRP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79672
GTEX Portal (Tissue expression)FN3KRP
Human Protein AtlasENSG00000141560-FN3KRP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HA64   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HA64  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HA64
Splice isoforms : SwissVarQ9HA64
Catalytic activity : Enzyme2.7.1.- [ Enzyme-Expasy ]   2.7.1.-2.7.1.- [ IntEnz-EBI ]   2.7.1.- [ BRENDA ]   2.7.1.- [ KEGG ]   
PhosPhoSitePlusQ9HA64
Domains : Interpro (EBI)Fructo-/Ketosamine-3-kinase    Kinase-like_dom_sf   
Domain families : Pfam (Sanger)Fructosamin_kin (PF03881)   
Domain families : Pfam (NCBI)pfam03881   
Conserved Domain (NCBI)FN3KRP
DMDM Disease mutations79672
Blocks (Seattle)FN3KRP
SuperfamilyQ9HA64
Human Protein Atlas [tissue]ENSG00000141560-FN3KRP [tissue]
Peptide AtlasQ9HA64
HPRD13546
IPIIPI00099986   IPI00911026   
Protein Interaction databases
DIP (DOE-UCLA)Q9HA64
IntAct (EBI)Q9HA64
FunCoupENSG00000141560
BioGRIDFN3KRP
STRING (EMBL)FN3KRP
ZODIACFN3KRP
Ontologies - Pathways
QuickGOQ9HA64
Ontology : AmiGOcytosol  kinase activity  kinase activity  phosphorylation  post-translational protein modification  
Ontology : EGO-EBIcytosol  kinase activity  kinase activity  phosphorylation  post-translational protein modification  
NDEx NetworkFN3KRP
Atlas of Cancer Signalling NetworkFN3KRP
Wikipedia pathwaysFN3KRP
Orthology - Evolution
OrthoDB79672
GeneTree (enSembl)ENSG00000141560
Phylogenetic Trees/Animal Genes : TreeFamFN3KRP
HOVERGENQ9HA64
HOGENOMQ9HA64
Homologs : HomoloGeneFN3KRP
Homology/Alignments : Family Browser (UCSC)FN3KRP
Gene fusions - Rearrangements
Fusion : MitelmanREV3L/FN3KRP [6q21/17q25.3]  [t(6;17)(q21;q25)]  
Fusion : MitelmanWSB1/FN3KRP [17q11.1/17q25.3]  [t(17;17)(q11;q25)]  
Fusion PortalREV3L 6q21 FN3KRP 17q25.3 LGG
Fusion PortalWSB1 17q11.1 FN3KRP 17q25.3 LUAD
Fusion : QuiverFN3KRP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFN3KRP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FN3KRP
dbVarFN3KRP
ClinVarFN3KRP
1000_GenomesFN3KRP 
Exome Variant ServerFN3KRP
ExAC (Exome Aggregation Consortium)ENSG00000141560
GNOMAD BrowserENSG00000141560
Varsome BrowserFN3KRP
Genetic variants : HAPMAP79672
Genomic Variants (DGV)FN3KRP [DGVbeta]
DECIPHERFN3KRP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFN3KRP 
Mutations
ICGC Data PortalFN3KRP 
TCGA Data PortalFN3KRP 
Broad Tumor PortalFN3KRP
OASIS PortalFN3KRP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFN3KRP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFN3KRP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FN3KRP
DgiDB (Drug Gene Interaction Database)FN3KRP
DoCM (Curated mutations)FN3KRP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FN3KRP (select a term)
intoGenFN3KRP
Cancer3DFN3KRP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611683   
Orphanet
DisGeNETFN3KRP
MedgenFN3KRP
Genetic Testing Registry FN3KRP
NextProtQ9HA64 [Medical]
TSGene79672
GENETestsFN3KRP
Target ValidationFN3KRP
Huge Navigator FN3KRP [HugePedia]
snp3D : Map Gene to Disease79672
BioCentury BCIQFN3KRP
ClinGenFN3KRP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79672
Chemical/Pharm GKB GenePA164720079
Clinical trialFN3KRP
Miscellaneous
canSAR (ICR)FN3KRP (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFN3KRP
EVEXFN3KRP
GoPubMedFN3KRP
iHOPFN3KRP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:06:55 CET 2018
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