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FNBP1L (formin binding protein 1 like)

Identity

Alias (NCBI)C1orf39
TOCA1
HGNC (Hugo) FNBP1L
HGNC Alias symbTOCA1
FLJ20275
HGNC Previous nameC1orf39
HGNC Previous namechromosome 1 open reading frame 39
 formin binding protein 1-like
LocusID (NCBI) 54874
Atlas_Id 53509
Location 1p22.1  [Link to chromosome band 1p22]
Location_base_pair Starts at 93448118 and ends at 93554661 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FNBP1L (1p22.1) / PTPRN2 (7q36.3)TMEM56 (1p21.3) / FNBP1L (1p22.1)TMEM56 1p21.3 / FNBP1L 1p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FNBP1L   20851
Cards
Entrez_Gene (NCBI)FNBP1L    formin binding protein 1 like
AliasesC1orf39; TOCA1
GeneCards (Weizmann)FNBP1L
Ensembl hg19 (Hinxton)ENSG00000137942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137942 [Gene_View]  ENSG00000137942 [Sequence]  chr1:93448118-93554661 [Contig_View]  FNBP1L [Vega]
ICGC DataPortalENSG00000137942
TCGA cBioPortalFNBP1L
AceView (NCBI)FNBP1L
Genatlas (Paris)FNBP1L
SOURCE (Princeton)FNBP1L
Genetics Home Reference (NIH)FNBP1L
Genomic and cartography
GoldenPath hg38 (UCSC)FNBP1L  -     chr1:93448118-93554661 +  1p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FNBP1L  -     1p22.1   [Description]    (hg19-Feb_2009)
GoldenPathFNBP1L - 1p22.1 [CytoView hg19]  FNBP1L - 1p22.1 [CytoView hg38]
ImmunoBaseENSG00000137942
Genome Data Viewer NCBIFNBP1L [Mapview hg19]  
OMIM608848   
Gene and transcription
Genbank (Entrez)AK000282 AK025526 AK026988 AK296767 AK299760
RefSeq transcript (Entrez)NM_001024948 NM_001164473 NM_017737
Consensus coding sequences : CCDS (NCBI)FNBP1L
Gene ExpressionFNBP1L [ NCBI-GEO ]   FNBP1L [ EBI - ARRAY_EXPRESS ]   FNBP1L [ SEEK ]   FNBP1L [ MEM ]
Gene Expression Viewer (FireBrowse)FNBP1L [ Firebrowse - Broad ]
GenevisibleExpression of FNBP1L in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54874
GTEX Portal (Tissue expression)FNBP1L
Human Protein AtlasENSG00000137942-FNBP1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T0N5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T0N5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T0N5
PhosPhoSitePlusQ5T0N5
Domaine pattern : Prosite (Expaxy)F_BAR (PS51741)    REM_1 (PS51860)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR_dom_sf    F_BAR    FCH_dom    FNBP1L    FNBP1L_F-BAR    FNBP1L_SH3    HR1_rho-bd    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)FCH (PF00611)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam00611    pfam00018   
Domain families : Smart (EMBL)FCH (SM00055)  SH3 (SM00326)  
Conserved Domain (NCBI)FNBP1L
SuperfamilyQ5T0N5
AlphaFold pdb e-kbQ5T0N5   
Human Protein Atlas [tissue]ENSG00000137942-FNBP1L [tissue]
HPRD12317
Protein Interaction databases
DIP (DOE-UCLA)Q5T0N5
IntAct (EBI)Q5T0N5
BioGRIDFNBP1L
STRING (EMBL)FNBP1L
ZODIACFNBP1L
Ontologies - Pathways
QuickGOQ5T0N5
Ontology : AmiGOprotein binding  cytoplasm  cytosol  cytosol  cytoskeleton  plasma membrane  cell cortex  vesicle budding from membrane  autophagy  signal transduction  lipid binding  membrane invagination  vesicle organization  vesicle transport along actin filament  cytoplasmic vesicle  cadherin binding  GTPase binding  positive regulation of filopodium assembly  cilium assembly  membrane organization  clathrin-dependent endocytosis  plasma membrane tubulation  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  cytosol  cytoskeleton  plasma membrane  cell cortex  vesicle budding from membrane  autophagy  signal transduction  lipid binding  membrane invagination  vesicle organization  vesicle transport along actin filament  cytoplasmic vesicle  cadherin binding  GTPase binding  positive regulation of filopodium assembly  cilium assembly  membrane organization  clathrin-dependent endocytosis  plasma membrane tubulation  
NDEx NetworkFNBP1L
Atlas of Cancer Signalling NetworkFNBP1L
Wikipedia pathwaysFNBP1L
Orthology - Evolution
OrthoDB54874
GeneTree (enSembl)ENSG00000137942
Phylogenetic Trees/Animal Genes : TreeFamFNBP1L
Homologs : HomoloGeneFNBP1L
Homology/Alignments : Family Browser (UCSC)FNBP1L
Gene fusions - Rearrangements
Fusion : MitelmanTMEM56/FNBP1L [1p21.3/1p22.1]  
Fusion : QuiverFNBP1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFNBP1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FNBP1L
dbVarFNBP1L
ClinVarFNBP1L
MonarchFNBP1L
1000_GenomesFNBP1L 
Exome Variant ServerFNBP1L
GNOMAD BrowserENSG00000137942
Varsome BrowserFNBP1L
ACMGFNBP1L variants
VarityQ5T0N5
Genomic Variants (DGV)FNBP1L [DGVbeta]
DECIPHERFNBP1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFNBP1L 
Mutations
ICGC Data PortalFNBP1L 
TCGA Data PortalFNBP1L 
Broad Tumor PortalFNBP1L
OASIS PortalFNBP1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFNBP1L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFNBP1L
Mutations and Diseases : HGMDFNBP1L
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFNBP1L
DgiDB (Drug Gene Interaction Database)FNBP1L
DoCM (Curated mutations)FNBP1L
CIViC (Clinical Interpretations of Variants in Cancer)FNBP1L
Cancer3DFNBP1L
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608848   
Orphanet
DisGeNETFNBP1L
MedgenFNBP1L
Genetic Testing Registry FNBP1L
NextProtQ5T0N5 [Medical]
GENETestsFNBP1L
Target ValidationFNBP1L
Huge Navigator FNBP1L [HugePedia]
ClinGenFNBP1L
Clinical trials, drugs, therapy
MyCancerGenomeFNBP1L
Protein Interactions : CTDFNBP1L
Pharm GKB GenePA128394675
PharosQ5T0N5
Clinical trialFNBP1L
Miscellaneous
canSAR (ICR)FNBP1L
HarmonizomeFNBP1L
DataMed IndexFNBP1L
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFNBP1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:09:43 CEST 2021

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