Atlas of Genetics and Cytogenetics in Oncology and Haematology


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FNBP1L (formin binding protein 1 like)

Identity

Alias_namesC1orf39
chromosome 1 open reading frame 39
formin binding protein 1-like
Alias_symbol (synonym)TOCA1
FLJ20275
Other alias
HGNC (Hugo) FNBP1L
LocusID (NCBI) 54874
Atlas_Id 53509
Location 1p22.1  [Link to chromosome band 1p22]
Location_base_pair Starts at 93448131 and ends at 93554661 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FNBP1L (1p22.1) / PTPRN2 (7q36.3)TMEM56 (1p21.3) / FNBP1L (1p22.1)TMEM56 1p21.3 / FNBP1L 1p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FNBP1L   20851
Cards
Entrez_Gene (NCBI)FNBP1L  54874  formin binding protein 1 like
AliasesC1orf39; TOCA1
GeneCards (Weizmann)FNBP1L
Ensembl hg19 (Hinxton)ENSG00000137942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137942 [Gene_View]  chr1:93448131-93554661 [Contig_View]  FNBP1L [Vega]
ICGC DataPortalENSG00000137942
TCGA cBioPortalFNBP1L
AceView (NCBI)FNBP1L
Genatlas (Paris)FNBP1L
WikiGenes54874
SOURCE (Princeton)FNBP1L
Genetics Home Reference (NIH)FNBP1L
Genomic and cartography
GoldenPath hg38 (UCSC)FNBP1L  -     chr1:93448131-93554661 +  1p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FNBP1L  -     1p22.1   [Description]    (hg19-Feb_2009)
EnsemblFNBP1L - 1p22.1 [CytoView hg19]  FNBP1L - 1p22.1 [CytoView hg38]
Mapping of homologs : NCBIFNBP1L [Mapview hg19]  FNBP1L [Mapview hg38]
OMIM608848   
Gene and transcription
Genbank (Entrez)AK000282 AK025526 AK026988 AK296767 AK299760
RefSeq transcript (Entrez)NM_001024948 NM_001164473 NM_017737
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FNBP1L
Cluster EST : UnigeneHs.134060 [ NCBI ]
CGAP (NCI)Hs.134060
Alternative Splicing GalleryENSG00000137942
Gene ExpressionFNBP1L [ NCBI-GEO ]   FNBP1L [ EBI - ARRAY_EXPRESS ]   FNBP1L [ SEEK ]   FNBP1L [ MEM ]
Gene Expression Viewer (FireBrowse)FNBP1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54874
GTEX Portal (Tissue expression)FNBP1L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T0N5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T0N5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T0N5
Splice isoforms : SwissVarQ5T0N5
PhosPhoSitePlusQ5T0N5
Domaine pattern : Prosite (Expaxy)F_BAR (PS51741)    SH3 (PS50002)   
Domains : Interpro (EBI)F_BAR    FCH_dom    FNBP1L    SH3_domain   
Domain families : Pfam (Sanger)FCH (PF00611)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam00611    pfam00018   
Domain families : Smart (EMBL)FCH (SM00055)  SH3 (SM00326)  
Conserved Domain (NCBI)FNBP1L
DMDM Disease mutations54874
Blocks (Seattle)FNBP1L
SuperfamilyQ5T0N5
Human Protein AtlasENSG00000137942
Peptide AtlasQ5T0N5
HPRD12317
IPIIPI00937956   IPI00646028   IPI00015580   IPI00607808   IPI00028718   IPI01013728   
Protein Interaction databases
DIP (DOE-UCLA)Q5T0N5
IntAct (EBI)Q5T0N5
FunCoupENSG00000137942
BioGRIDFNBP1L
STRING (EMBL)FNBP1L
ZODIACFNBP1L
Ontologies - Pathways
QuickGOQ5T0N5
Ontology : AmiGOprotein binding  cytoplasm  cytosol  cytoskeleton  plasma membrane  cell cortex  membrane budding  autophagy  lipid binding  membrane invagination  vesicle organization  vesicle transport along actin filament  cytoplasmic vesicle  cadherin binding  GTPase binding  positive regulation of filopodium assembly  cilium assembly  membrane organization  extracellular exosome  clathrin-dependent endocytosis  plasma membrane tubulation  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  cytoskeleton  plasma membrane  cell cortex  membrane budding  autophagy  lipid binding  membrane invagination  vesicle organization  vesicle transport along actin filament  cytoplasmic vesicle  cadherin binding  GTPase binding  positive regulation of filopodium assembly  cilium assembly  membrane organization  extracellular exosome  clathrin-dependent endocytosis  plasma membrane tubulation  
NDEx NetworkFNBP1L
Atlas of Cancer Signalling NetworkFNBP1L
Wikipedia pathwaysFNBP1L
Orthology - Evolution
OrthoDB54874
GeneTree (enSembl)ENSG00000137942
Phylogenetic Trees/Animal Genes : TreeFamFNBP1L
HOVERGENQ5T0N5
HOGENOMQ5T0N5
Homologs : HomoloGeneFNBP1L
Homology/Alignments : Family Browser (UCSC)FNBP1L
Gene fusions - Rearrangements
Fusion : MitelmanTMEM56/FNBP1L [1p21.3/1p22.1]  [t(1;1)(p21;p22)]  
Fusion: TCGATMEM56 1p21.3 FNBP1L 1p22.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFNBP1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FNBP1L
dbVarFNBP1L
ClinVarFNBP1L
1000_GenomesFNBP1L 
Exome Variant ServerFNBP1L
ExAC (Exome Aggregation Consortium)FNBP1L (select the gene name)
Genetic variants : HAPMAP54874
Genomic Variants (DGV)FNBP1L [DGVbeta]
DECIPHERFNBP1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFNBP1L 
Mutations
ICGC Data PortalFNBP1L 
TCGA Data PortalFNBP1L 
Broad Tumor PortalFNBP1L
OASIS PortalFNBP1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFNBP1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFNBP1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FNBP1L
DgiDB (Drug Gene Interaction Database)FNBP1L
DoCM (Curated mutations)FNBP1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FNBP1L (select a term)
intoGenFNBP1L
Cancer3DFNBP1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608848   
Orphanet
MedgenFNBP1L
Genetic Testing Registry FNBP1L
NextProtQ5T0N5 [Medical]
TSGene54874
GENETestsFNBP1L
Target ValidationFNBP1L
Huge Navigator FNBP1L [HugePedia]
snp3D : Map Gene to Disease54874
BioCentury BCIQFNBP1L
ClinGenFNBP1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54874
Chemical/Pharm GKB GenePA128394675
Clinical trialFNBP1L
Miscellaneous
canSAR (ICR)FNBP1L (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFNBP1L
EVEXFNBP1L
GoPubMedFNBP1L
iHOPFNBP1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:34:10 CEST 2017

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