FNDC1 (fibronectin type III domain containing 1)

2007-02-01  

Identity

HGNC
FNDC1
LOCATION
6q25.3
LOCUSID
84624
ALIAS
AGS8,FNDC2,MEL4B3,bA243O10.1,dJ322A24.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84624
MIM: 609991
HGNC: 21184
Ensembl: ENSG00000164694

Variants:

dbSNP: 84624
ClinVar: 84624
TCGA: ENSG00000164694
COSMIC: FNDC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164694ENST00000297267Q4ZHG4
ENSG00000164694ENST00000329629J3KNQ2

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
146573972003Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates.79
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
276934932016miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin.16
160981312005MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF-beta and pro-inflammatory cytokines.8
268261882016Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis.5
296494272018VEGFR-3 signaling is regulated by a G-protein activator, activator of G-protein signaling 8, in lymphatic endothelial cells.3
315300962019Overexpression of FNDC1 Relates to Poor Prognosis and Its Knockdown Impairs Cell Invasion and Migration in Gastric Cancer.0

Citation

Dessen P

FNDC1 (fibronectin type III domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45579/fndc1