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FNDC1 (fibronectin type III domain containing 1)

Identity

Alias_namesFNDC2
fibronectin type III domain containing 2
Alias_symbol (synonym)bA243O10.1
KIAA1866
dJ322A24.1
Other aliasAGS8
MEL4B3
HGNC (Hugo) FNDC1
LocusID (NCBI) 84624
Atlas_Id 45579
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 159169397 and ends at 159272108 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAP3K4 (6q26) / FNDC1 (6q25.3)MAP3K4 6q26 / FNDC1 6q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(q25;q26) MAP3K4/FNDC1


External links

Nomenclature
HGNC (Hugo)FNDC1   21184
Cards
Entrez_Gene (NCBI)FNDC1  84624  fibronectin type III domain containing 1
AliasesAGS8; FNDC2; MEL4B3; bA243O10.1; 
dJ322A24.1
GeneCards (Weizmann)FNDC1
Ensembl hg19 (Hinxton)ENSG00000164694 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164694 [Gene_View]  ENSG00000164694 [Sequence]  chr6:159169397-159272108 [Contig_View]  FNDC1 [Vega]
ICGC DataPortalENSG00000164694
TCGA cBioPortalFNDC1
AceView (NCBI)FNDC1
Genatlas (Paris)FNDC1
WikiGenes84624
SOURCE (Princeton)FNDC1
Genetics Home Reference (NIH)FNDC1
Genomic and cartography
GoldenPath hg38 (UCSC)FNDC1  -     chr6:159169397-159272108 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FNDC1  -     6q25.3   [Description]    (hg19-Feb_2009)
EnsemblFNDC1 - 6q25.3 [CytoView hg19]  FNDC1 - 6q25.3 [CytoView hg38]
Mapping of homologs : NCBIFNDC1 [Mapview hg19]  FNDC1 [Mapview hg38]
OMIM609991   
Gene and transcription
Genbank (Entrez)AB058769 AJ586132 AK127635 AL832410 BC146783
RefSeq transcript (Entrez)NM_032532
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FNDC1
Cluster EST : UnigeneHs.520525 [ NCBI ]
CGAP (NCI)Hs.520525
Alternative Splicing GalleryENSG00000164694
Gene ExpressionFNDC1 [ NCBI-GEO ]   FNDC1 [ EBI - ARRAY_EXPRESS ]   FNDC1 [ SEEK ]   FNDC1 [ MEM ]
Gene Expression Viewer (FireBrowse)FNDC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84624
GTEX Portal (Tissue expression)FNDC1
Human Protein AtlasENSG00000164694-FNDC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4ZHG4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4ZHG4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4ZHG4
Splice isoforms : SwissVarQ4ZHG4
PhosPhoSitePlusQ4ZHG4
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)   
Domains : Interpro (EBI)FN3_dom    FN3_sf    Ig-like_fold   
Domain families : Pfam (Sanger)fn3 (PF00041)   
Domain families : Pfam (NCBI)pfam00041   
Domain families : Smart (EMBL)FN3 (SM00060)  
Conserved Domain (NCBI)FNDC1
DMDM Disease mutations84624
Blocks (Seattle)FNDC1
SuperfamilyQ4ZHG4
Human Protein Atlas [tissue]ENSG00000164694-FNDC1 [tissue]
Peptide AtlasQ4ZHG4
HPRD13547
IPIIPI00306457   IPI00844416   
Protein Interaction databases
DIP (DOE-UCLA)Q4ZHG4
IntAct (EBI)Q4ZHG4
FunCoupENSG00000164694
BioGRIDFNDC1
STRING (EMBL)FNDC1
ZODIACFNDC1
Ontologies - Pathways
QuickGOQ4ZHG4
Ontology : AmiGOextracellular region  nuclear speck  
Ontology : EGO-EBIextracellular region  nuclear speck  
NDEx NetworkFNDC1
Atlas of Cancer Signalling NetworkFNDC1
Wikipedia pathwaysFNDC1
Orthology - Evolution
OrthoDB84624
GeneTree (enSembl)ENSG00000164694
Phylogenetic Trees/Animal Genes : TreeFamFNDC1
HOVERGENQ4ZHG4
HOGENOMQ4ZHG4
Homologs : HomoloGeneFNDC1
Homology/Alignments : Family Browser (UCSC)FNDC1
Gene fusions - Rearrangements
Fusion : MitelmanMAP3K4/FNDC1 [6q26/6q25.3]  [t(6;6)(q25;q26)]  
Fusion PortalMAP3K4 6q26 FNDC1 6q25.3 BRCA
Fusion : QuiverFNDC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFNDC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FNDC1
dbVarFNDC1
ClinVarFNDC1
1000_GenomesFNDC1 
Exome Variant ServerFNDC1
ExAC (Exome Aggregation Consortium)ENSG00000164694
GNOMAD BrowserENSG00000164694
Varsome BrowserFNDC1
Genetic variants : HAPMAP84624
Genomic Variants (DGV)FNDC1 [DGVbeta]
DECIPHERFNDC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFNDC1 
Mutations
ICGC Data PortalFNDC1 
TCGA Data PortalFNDC1 
Broad Tumor PortalFNDC1
OASIS PortalFNDC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFNDC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFNDC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FNDC1
DgiDB (Drug Gene Interaction Database)FNDC1
DoCM (Curated mutations)FNDC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FNDC1 (select a term)
intoGenFNDC1
Cancer3DFNDC1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609991   
Orphanet
DisGeNETFNDC1
MedgenFNDC1
Genetic Testing Registry FNDC1
NextProtQ4ZHG4 [Medical]
TSGene84624
GENETestsFNDC1
Target ValidationFNDC1
Huge Navigator FNDC1 [HugePedia]
snp3D : Map Gene to Disease84624
BioCentury BCIQFNDC1
ClinGenFNDC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84624
Chemical/Pharm GKB GenePA134906656
Clinical trialFNDC1
Miscellaneous
canSAR (ICR)FNDC1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFNDC1
EVEXFNDC1
GoPubMedFNDC1
iHOPFNDC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:06:56 CET 2018

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