FNDC3B (fibronectin type III domain containing 3B)

2009-09-01  

Identity

HGNC
LOCATION
3q26.31
LOCUSID
ALIAS
FAD104,PRO4979,YVTM2421
FUSION GENES

Other Information

Locus ID:

NCBI: 64778
MIM: 611909
HGNC: 24670
Ensembl: ENSG00000075420

Variants:

dbSNP: 64778
ClinVar: 64778
TCGA: ENSG00000075420
COSMIC: FNDC3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000075420ENST00000336824Q53EP0
ENSG00000075420ENST00000415807Q53EP0
ENSG00000075420ENST00000416957Q53EP0
ENSG00000075420ENST00000421757Q53EP0
ENSG00000075420ENST00000423424Q53EP0
ENSG00000075420ENST00000443501C9JKH7

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194723112009Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression.136
232915892013Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.105
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
304587842018Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis.30
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
225106132012Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B.26
315410922019Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis.18
280686302017Potential mechanisms of microRNA-129-5p in inhibiting cell processes including viability, proliferation, migration and invasiveness of glioblastoma cells U87 through targeting FNDC3B.15
273852172016FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma.13
256715702015Fad104, a positive regulator of adipocyte differentiation, suppresses invasion and metastasis of melanoma cells by inhibition of STAT3 activity.5

Citation

Dessen P

FNDC3B (fibronectin type III domain containing 3B)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51071/fndc3b