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FNDC3B (fibronectin type III domain containing 3B)

Identity

Alias_symbol (synonym)FAD104
DKFZp762K137
FLJ23399
PRO4979
YVTM2421
Other alias
HGNC (Hugo) FNDC3B
LocusID (NCBI) 64778
Atlas_Id 51071
Location 3q26.31  [Link to chromosome band 3q26]
Location_base_pair Starts at 172040554 and ends at 172400702 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FKBP5 (6p21.31) / FNDC3B (3q26.31)FNDC3B (3q26.31) / FNDC3B (3q26.31)FNDC3B (3q26.31) / GORASP2 (2q31.1)
FNDC3B (3q26.31) / KHDRBS3 (8q24.23)FNDC3B (3q26.31) / NAALADL2 (3q26.31)FNDC3B (3q26.31) / NLGN1 (3q26.31)
FNDC3B (3q26.31) / PIK3CA (3q26.32)FNDC3B (3q26.31) / PITPNC1 (17q24.2)FNDC3B (3q26.31) / SPATA16 (3q26.31)
FNDC3B (3q26.31) / UCK2 (1q24.1)MST1R (3p21.31) / FNDC3B (3q26.31)NSUN5P1 (7q11.23) / FNDC3B (3q26.31)
PHC3 (3q26.2) / FNDC3B (3q26.31)RAD51B (14q24.1) / FNDC3B (3q26.31)SAT1 (Xp22.11) / FNDC3B (3q26.31)
FNDC3B 3q26.31 / KHDRBS3 8q24.23FNDC3B 3q26.31 / NAALADL2 3q26.31FNDC3B 3q26.31 / NLGN1 3q26.31
FNDC3B 3q26.31 / SPATA16 3q26.31FNDC3B 3q26.31 / UCK2 1q24.1MST1R 3p21.31 / FNDC3B 3q26.31
PHC3 3q26.2 / FNDC3B 3q26.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)FNDC3B   24670
Cards
Entrez_Gene (NCBI)FNDC3B  64778  fibronectin type III domain containing 3B
AliasesFAD104; PRO4979; YVTM2421
GeneCards (Weizmann)FNDC3B
Ensembl hg19 (Hinxton)ENSG00000075420 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075420 [Gene_View]  chr3:172040554-172400702 [Contig_View]  FNDC3B [Vega]
ICGC DataPortalENSG00000075420
TCGA cBioPortalFNDC3B
AceView (NCBI)FNDC3B
Genatlas (Paris)FNDC3B
WikiGenes64778
SOURCE (Princeton)FNDC3B
Genetics Home Reference (NIH)FNDC3B
Genomic and cartography
GoldenPath hg38 (UCSC)FNDC3B  -     chr3:172040554-172400702 +  3q26.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FNDC3B  -     3q26.31   [Description]    (hg19-Feb_2009)
EnsemblFNDC3B - 3q26.31 [CytoView hg19]  FNDC3B - 3q26.31 [CytoView hg38]
Mapping of homologs : NCBIFNDC3B [Mapview hg19]  FNDC3B [Mapview hg38]
OMIM611909   
Gene and transcription
Genbank (Entrez)AB098597 AF543840 AI417065 AK027052 AK075220
RefSeq transcript (Entrez)NM_001135095 NM_022763
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FNDC3B
Cluster EST : UnigeneHs.744888 [ NCBI ]
CGAP (NCI)Hs.744888
Alternative Splicing GalleryENSG00000075420
Gene ExpressionFNDC3B [ NCBI-GEO ]   FNDC3B [ EBI - ARRAY_EXPRESS ]   FNDC3B [ SEEK ]   FNDC3B [ MEM ]
Gene Expression Viewer (FireBrowse)FNDC3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64778
GTEX Portal (Tissue expression)FNDC3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53EP0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53EP0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53EP0
Splice isoforms : SwissVarQ53EP0
PhosPhoSitePlusQ53EP0
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)   
Domains : Interpro (EBI)FN3_dom    Ig-like_fold   
Domain families : Pfam (Sanger)fn3 (PF00041)   
Domain families : Pfam (NCBI)pfam00041   
Domain families : Smart (EMBL)FN3 (SM00060)  
Conserved Domain (NCBI)FNDC3B
DMDM Disease mutations64778
Blocks (Seattle)FNDC3B
SuperfamilyQ53EP0
Human Protein AtlasENSG00000075420
Peptide AtlasQ53EP0
HPRD10943
IPIIPI00217490   IPI00798122   IPI00386472   IPI00953521   
Protein Interaction databases
DIP (DOE-UCLA)Q53EP0
IntAct (EBI)Q53EP0
FunCoupENSG00000075420
BioGRIDFNDC3B
STRING (EMBL)FNDC3B
ZODIACFNDC3B
Ontologies - Pathways
QuickGOQ53EP0
Ontology : AmiGORNA binding  integral component of membrane  
Ontology : EGO-EBIRNA binding  integral component of membrane  
NDEx NetworkFNDC3B
Atlas of Cancer Signalling NetworkFNDC3B
Wikipedia pathwaysFNDC3B
Orthology - Evolution
OrthoDB64778
GeneTree (enSembl)ENSG00000075420
Phylogenetic Trees/Animal Genes : TreeFamFNDC3B
HOVERGENQ53EP0
HOGENOMQ53EP0
Homologs : HomoloGeneFNDC3B
Homology/Alignments : Family Browser (UCSC)FNDC3B
Gene fusions - Rearrangements
Fusion : MitelmanFNDC3B/KHDRBS3 [3q26.31/8q24.23]  
Fusion : MitelmanFNDC3B/NAALADL2 [3q26.31/3q26.31]  [t(3;3)(q26;q26)]  
Fusion : MitelmanFNDC3B/NLGN1 [3q26.31/3q26.31]  [t(3;3)(q26;q26)]  
Fusion : MitelmanFNDC3B/SPATA16 [3q26.31/3q26.31]  [t(3;3)(q26;q26)]  
Fusion : MitelmanFNDC3B/UCK2 [3q26.31/1q24.1]  [t(1;3)(q24;q26)]  
Fusion : MitelmanMST1R/FNDC3B [3p21.31/3q26.31]  [t(3;3)(p21;q26)]  
Fusion : MitelmanPHC3/FNDC3B [3q26.2/3q26.31]  [t(3;3)(q26;q26)]  
Fusion: TCGAFNDC3B 3q26.31 KHDRBS3 8q24.23 LUAD
Fusion: TCGAFNDC3B 3q26.31 NAALADL2 3q26.31 LUSC
Fusion: TCGAFNDC3B 3q26.31 NLGN1 3q26.31 BRCA
Fusion: TCGAFNDC3B 3q26.31 SPATA16 3q26.31 LUSC
Fusion: TCGAFNDC3B 3q26.31 UCK2 1q24.1 BRCA
Fusion: TCGAMST1R 3p21.31 FNDC3B 3q26.31 LUAD
Fusion: TCGAPHC3 3q26.2 FNDC3B 3q26.31 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFNDC3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FNDC3B
dbVarFNDC3B
ClinVarFNDC3B
1000_GenomesFNDC3B 
Exome Variant ServerFNDC3B
ExAC (Exome Aggregation Consortium)FNDC3B (select the gene name)
Genetic variants : HAPMAP64778
Genomic Variants (DGV)FNDC3B [DGVbeta]
DECIPHERFNDC3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFNDC3B 
Mutations
ICGC Data PortalFNDC3B 
TCGA Data PortalFNDC3B 
Broad Tumor PortalFNDC3B
OASIS PortalFNDC3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFNDC3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFNDC3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FNDC3B
DgiDB (Drug Gene Interaction Database)FNDC3B
DoCM (Curated mutations)FNDC3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FNDC3B (select a term)
intoGenFNDC3B
Cancer3DFNDC3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611909   
Orphanet
MedgenFNDC3B
Genetic Testing Registry FNDC3B
NextProtQ53EP0 [Medical]
TSGene64778
GENETestsFNDC3B
Target ValidationFNDC3B
Huge Navigator FNDC3B [HugePedia]
snp3D : Map Gene to Disease64778
BioCentury BCIQFNDC3B
ClinGenFNDC3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64778
Chemical/Pharm GKB GenePA134936830
Clinical trialFNDC3B
Miscellaneous
canSAR (ICR)FNDC3B (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFNDC3B
EVEXFNDC3B
GoPubMedFNDC3B
iHOPFNDC3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:08:44 CEST 2017

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