Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

FOCAD (focadhesin)

Identity

Alias_namesKIAA1797
KIAA1797
Alias_symbol (synonym)FLJ20375
Other alias
HGNC (Hugo) FOCAD
LocusID (NCBI) 54914
Atlas_Id 52756
Location 9p21.3  [Link to chromosome band 9p21]
Location_base_pair Starts at 20658309 and ends at 20995955 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CDKN2A (9p21.3) / FOCAD (9p21.3)FOCAD (9p21.3) / C10orf90 (10q26.2)FOCAD (9p21.3) / CDKN2A (9p21.3)
FOCAD (9p21.3) / CDKN2B-AS1 (9p21.3)FOCAD (9p21.3) / HACD4 (9p21.3)FOCAD (9p21.3) / IFT74 (9p21.2)
FOCAD (9p21.3) / MALAT1 (11q13.1)FOCAD (9p21.3) / MOB3B (9p21.2)FOCAD (9p21.3) / PDZRN4 (12q12)
FOCAD (9p21.3) / UNC13B (9p13.3)UNC13B (9p13.3) / FOCAD (9p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)FOCAD   23377
Cards
Entrez_Gene (NCBI)FOCAD  54914  focadhesin
AliasesKIAA1797
GeneCards (Weizmann)FOCAD
Ensembl hg19 (Hinxton)ENSG00000188352 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188352 [Gene_View]  chr9:20658309-20995955 [Contig_View]  FOCAD [Vega]
ICGC DataPortalENSG00000188352
TCGA cBioPortalFOCAD
AceView (NCBI)FOCAD
Genatlas (Paris)FOCAD
WikiGenes54914
SOURCE (Princeton)FOCAD
Genetics Home Reference (NIH)FOCAD
Genomic and cartography
GoldenPath hg38 (UCSC)FOCAD  -     chr9:20658309-20995955 +  9p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FOCAD  -     9p21.3   [Description]    (hg19-Feb_2009)
EnsemblFOCAD - 9p21.3 [CytoView hg19]  FOCAD - 9p21.3 [CytoView hg38]
Mapping of homologs : NCBIFOCAD [Mapview hg19]  FOCAD [Mapview hg38]
OMIM614606   
Gene and transcription
Genbank (Entrez)AB058700 AK000382 AK055116 AK056522 AK172818
RefSeq transcript (Entrez)NM_017794
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FOCAD
Cluster EST : UnigeneHs.136247 [ NCBI ]
CGAP (NCI)Hs.136247
Alternative Splicing GalleryENSG00000188352
Gene ExpressionFOCAD [ NCBI-GEO ]   FOCAD [ EBI - ARRAY_EXPRESS ]   FOCAD [ SEEK ]   FOCAD [ MEM ]
Gene Expression Viewer (FireBrowse)FOCAD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54914
GTEX Portal (Tissue expression)FOCAD
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VW36   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VW36  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VW36
Splice isoforms : SwissVarQ5VW36
PhosPhoSitePlusQ5VW36
Domains : Interpro (EBI)ARM-type_fold    DUF3730    Focadhesin   
Domain families : Pfam (Sanger)DUF3730 (PF12530)    Focadhesin (PF11229)   
Domain families : Pfam (NCBI)pfam12530    pfam11229   
Conserved Domain (NCBI)FOCAD
DMDM Disease mutations54914
Blocks (Seattle)FOCAD
SuperfamilyQ5VW36
Human Protein AtlasENSG00000188352
Peptide AtlasQ5VW36
HPRD11162
IPIIPI00748360   
Protein Interaction databases
DIP (DOE-UCLA)Q5VW36
IntAct (EBI)Q5VW36
FunCoupENSG00000188352
BioGRIDFOCAD
STRING (EMBL)FOCAD
ZODIACFOCAD
Ontologies - Pathways
QuickGOQ5VW36
Ontology : AmiGOprotein binding  focal adhesion  integral component of membrane  
Ontology : EGO-EBIprotein binding  focal adhesion  integral component of membrane  
NDEx NetworkFOCAD
Atlas of Cancer Signalling NetworkFOCAD
Wikipedia pathwaysFOCAD
Orthology - Evolution
OrthoDB54914
GeneTree (enSembl)ENSG00000188352
Phylogenetic Trees/Animal Genes : TreeFamFOCAD
HOVERGENQ5VW36
HOGENOMQ5VW36
Homologs : HomoloGeneFOCAD
Homology/Alignments : Family Browser (UCSC)FOCAD
Gene fusions - Rearrangements
Fusion : MitelmanCDKN2A/FOCAD [9p21.3/9p21.3]  [t(9;9)(p21;p21)]  
Fusion : MitelmanFOCAD/C10orf90 [9p21.3/10q26.2]  [t(9;10)(p21;q26)]  
Fusion : MitelmanFOCAD/CDKN2A [9p21.3/9p21.3]  [t(9;9)(p21;p21)]  
Fusion : MitelmanFOCAD/HACD4 [9p21.3/9p21.3]  [t(9;9)(p21;p21)]  
Fusion : MitelmanFOCAD/MOB3B [9p21.3/9p21.2]  [t(9;9)(p21;p21)]  
Fusion : MitelmanFOCAD/PDZRN4 [9p21.3/12q12]  [t(9;12)(p21;q12)]  
Fusion Cancer (Beijing)FOCAD [9p21.3]  -  UNC13B [9p13.3]  [FUSC002372]
Fusion Cancer (Beijing)UNC13B [9p13.3]  -  FOCAD [9p21.3]  [FUSC002386]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFOCAD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FOCAD
dbVarFOCAD
ClinVarFOCAD
1000_GenomesFOCAD 
Exome Variant ServerFOCAD
ExAC (Exome Aggregation Consortium)FOCAD (select the gene name)
Genetic variants : HAPMAP54914
Genomic Variants (DGV)FOCAD [DGVbeta]
DECIPHERFOCAD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFOCAD 
Mutations
ICGC Data PortalFOCAD 
TCGA Data PortalFOCAD 
Broad Tumor PortalFOCAD
OASIS PortalFOCAD [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDFOCAD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FOCAD
DgiDB (Drug Gene Interaction Database)FOCAD
DoCM (Curated mutations)FOCAD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FOCAD (select a term)
intoGenFOCAD
Cancer3DFOCAD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614606   
Orphanet
MedgenFOCAD
Genetic Testing Registry FOCAD
NextProtQ5VW36 [Medical]
TSGene54914
GENETestsFOCAD
Target ValidationFOCAD
Huge Navigator FOCAD [HugePedia]
snp3D : Map Gene to Disease54914
BioCentury BCIQFOCAD
ClinGenFOCAD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54914
Chemical/Pharm GKB GenePA134934777
Clinical trialFOCAD
Miscellaneous
canSAR (ICR)FOCAD (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFOCAD
EVEXFOCAD
GoPubMedFOCAD
iHOPFOCAD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:34:11 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.